Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL230W
Length:
335
Number of sequences:
5887
Description:
YDL230W PTP1 SGDID:S000002389, Chr IV from 42700-43707, Genome Release 64-1-1, Verified ORF, "Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P23469    700   PTPRE_HUMAN Receptor-type tyrosine-protein ph...2852e-27     117     32     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
62Q9W6V5    1406   PTPRJ_CHICK Receptor-type tyrosine-protein ph...2774e-29     123     33     48GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.
63O82656    340   PTP1_ARATH Protein-tyrosine-phosphatase PTP1 ...3251e-28     117     30     46GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; TAS:TAIR.
64O08617    656   PTPRR_RAT Receptor-type tyrosine-protein phos...2891e-28     120     33     46GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0001701; P:in utero embryonic development; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD.
65Q62132    656   PTPRR_MOUSE Receptor-type tyrosine-protein ph...2892e-28     120     33     46GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
66Q62136    1176   PTN21_MOUSE Tyrosine-protein phosphatase non-...2862e-28     121     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
67Q62728    1175   PTN21_RAT Tyrosine-protein phosphatase non-re...2862e-28     121     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0007010; P:cytoskeleton organization; NAS:RGD.
68Q64512    2453   PTN13_MOUSE Tyrosine-protein phosphatase non-...2803e-28     121     30     46GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
69P16620    1462   PTP69_DROME Tyrosine-protein phosphatase 69D ...3030.0000000002     65.5     25     43GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007415; P:defasciculation of motor neuron axon; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.
70Q16825    1174   PTN21_HUMAN Tyrosine-protein phosphatase non-...2861e-27     119     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
71Q8BUM3    359   PTN7_MOUSE Tyrosine-protein phosphatase non-r...2791e-27     115     31     47
GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.
72Q12913    1337   PTPRJ_HUMAN Receptor-type tyrosine-protein ph...2811e-27     119     33     46GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0060242; P:contact inhibition; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0050918; P:positive chemotaxis; IDA:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0045885; P:positive regulation of survival gene product expression; IDA:UniProtKB.
73Q9Y2R2    807   PTN22_HUMAN Tyrosine-protein phosphatase non-...3071e-27     118     27     47GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019900; F:kinase binding; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; ISS:BHF-UCL.::GO:0050855; P:regulation of B cell receptor signaling pathway; NAS:BHF-UCL.::GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; IDA:BHF-UCL.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.
74P49445    359   PTN7_RAT Tyrosine-protein phosphatase non-rec...2792e-27     114     31     47GO:0005829; C:cytosol; IDA:RGD.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
75P18052    829   PTPRA_MOUSE Receptor-type tyrosine-protein ph...3153e-26     114     30     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.
76Q9IBD8    1216   PTPRC_CYPCA Receptor-type tyrosine-protein ph...3010.000000000000004     80.1     26     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro.
77Q15678    1187   PTN14_HUMAN Tyrosine-protein phosphatase non-...2861e-26     115     34     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
78P35236    360   PTN7_HUMAN Tyrosine-protein phosphatase non-r...2893e-26     110     30     45GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
79A1L1L3    421   PTN20_RAT Tyrosine-protein phosphatase non-re...2785e-26     110     31     46GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
80Q64455    1238   PTPRJ_MOUSE Receptor-type tyrosine-protein ph...2856e-26     113     33     47GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.
GO:0007596; P:blood coagulation; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.::GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000272; P:negative regulation of receptor activity; IMP:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:UniProtKB.::GO:0010572; P:positive regulation of platelet activation; IMP:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:MGI.
81Q62130    1189   PTN14_MOUSE Tyrosine-protein phosphatase non-...2867e-26     113     33     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
82P29352    802   PTN22_MOUSE Tyrosine-protein phosphatase non-...3062e-25     111     28     45GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI.
83Q9HD43    1115   PTPRH_HUMAN Receptor-type tyrosine-protein ph...2855e-25     110     29     46GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
84P29074    926   PTN4_HUMAN Tyrosine-protein phosphatase non-r...3206e-25     110     28     44GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
85P54830    541   PTN5_MOUSE Tyrosine-protein phosphatase non-r...2941e-24     108     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.
86Q9WU22    926   PTN4_MOUSE Tyrosine-protein phosphatase non-r...3202e-24     108     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.
87P34137    522   PTP1_DICDI Tyrosine-protein phosphatase 1 OS=...2622e-24     107     34     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
88P35234    369   PTN5_RAT Tyrosine-protein phosphatase non-rec...2945e-24     104     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
89B3DK56    1444   PTPRU_DANRE Receptor-type tyrosine-protein ph...3000.00000000002     68.6     25     41GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001757; P:somite specification; IMP:ZFIN.
90P43378    593   PTN9_HUMAN Tyrosine-protein phosphatase non-r...3002e-23     105     28     41GO:0044444; C:cytoplasmic part; IDA:UniProtKB.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
91P54637    990   PTP3_DICDI Tyrosine-protein phosphatase 3 OS=...2842e-23     105     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IMP:dictyBase.::GO:0034504; P:protein localization to nucleus; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IMP:dictyBase.::GO:0042501; P:serine phosphorylation of STAT protein; IMP:dictyBase.
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