Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL230W
Length:
335
Number of sequences:
5887
Description:
YDL230W PTP1 SGDID:S000002389, Chr IV from 42700-43707, Genome Release 64-1-1, Verified ORF, "Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q98936    1422   PTPRG_CHICK Receptor-type tyrosine-protein ph...2260.00001     50.8     27     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
32P06800    1291   PTPRC_MOUSE Receptor-type tyrosine-protein ph...3090.0000000000001     75.5     25     39GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0043395; F:heparan sulfate proteoglycan binding; IDA:MGI.::GO:0008201; F:heparin binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0042100; P:B cell proliferation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0034113; P:heterotypic cell-cell adhesion; IMP:MGI.::GO:0007159; P:leukocyte cell-cell adhesion; IMP:MGI.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0031953; P:negative regulation of protein autophosphorylation; IMP:MGI.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IMP:UniProtKB.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030890; P:positive regulation of B cell proliferation; IMP:MGI.::GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IMP:MGI.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IMP:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:MGI.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0042098; P:T cell proliferation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
33O14522    1441   PTPRT_HUMAN Receptor-type tyrosine-protein ph...2920.000000001     63.5     22     43GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0045294; F:alpha-catenin binding; IDA:UniProtKB.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045296; F:cadherin binding; IPI:UniProtKB.::GO:0070097; F:delta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.
34Q99M80    1454   PTPRT_MOUSE Receptor-type tyrosine-protein ph...2920.000000001     63.5     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0051393; F:alpha-actinin binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0008013; F:beta-catenin binding; IDA:MGI.::GO:0045296; F:cadherin binding; IPI:MGI.::GO:0070097; F:delta-catenin binding; IPI:MGI.::GO:0045295; F:gamma-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IMP:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0016790; F:thiolester hydrolase activity; IDA:MGI.
35P28827    1452   PTPRM_HUMAN Receptor-type tyrosine-protein ph...2930.0000000004     64.7     25     40GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0045296; F:cadherin binding; IDA:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0010842; P:retina layer formation; IMP:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB.
36P08575    1304   PTPRC_HUMAN Receptor-type tyrosine-protein ph...3050.00000000000005     76.6     25     41GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0048539; P:bone marrow development; IMP:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:UniProtKB.::GO:0002378; P:immunoglobulin biosynthetic process; IMP:UniProtKB.::GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IMP:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:2000473; P:positive regulation of hematopoietic stem cell migration; IMP:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; NAS:UniProtKB.::GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0048864; P:stem cell development; IMP:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
37E9Q612    1226   PTPRO_MOUSE Receptor-type tyrosine-protein ph...2864e-31     129     33     49GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0043197; C:dendritic spine; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016328; C:lateral plasma membrane; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0017147; F:Wnt-protein binding; IDA:UniProtKB.
GO:0007411; P:axon guidance; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; IMP:UniProtKB.::GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.::GO:0002548; P:monocyte chemotaxis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.::GO:0036060; P:slit diaphragm assembly; IMP:UniProtKB.
38P35822    1457   PTPRK_MOUSE Receptor-type tyrosine-protein ph...2940.000002     53.5     22     41GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
39P35832    1301   PTP99_DROME Tyrosine-protein phosphatase 99A ...2350.00009     48.1     25     41GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:FlyBase.
GO:0007415; P:defasciculation of motor neuron axon; IGI:FlyBase.::GO:0008045; P:motor axon guidance; IGI:FlyBase.
40O88488    2302   PTPRQ_RAT Phosphotidylinositol phosphatase PT...2846e-31     129     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
41P28828    1452   PTPRM_MOUSE Receptor-type tyrosine-protein ph...2930.0000000005     64.3     25     40GO:0005913; C:cell-cell adherens junction; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0045296; F:cadherin binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0045909; P:positive regulation of vasodilation; IMP:MGI.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB.
42Q15262    1439   PTPRK_HUMAN Receptor-type tyrosine-protein ph...2940.000002     53.5     22     41GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.::GO:0031256; C:leading edge membrane; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
43P0C5E4    2300   PTPRQ_MOUSE Phosphotidylinositol phosphatase ...2841e-30     128     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
44Q9UMZ3    2332   PTPRQ_HUMAN Phosphotidylinositol phosphatase ...2841e-30     128     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0045598; P:regulation of fat cell differentiation; IDA:UniProtKB.
45B2GV87    699   PTPRE_RAT Receptor-type tyrosine-protein phos...2857e-28     118     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; NAS:RGD.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
46P20417    432   PTN1_RAT Tyrosine-protein phosphatase non-rec...2782e-30     124     30     47GO:0031225; C:anchored to membrane; NAS:RGD.::GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.
GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IMP:RGD.
47B2RU80    1998   PTPRB_MOUSE Receptor-type tyrosine-protein ph...2942e-30     127     32     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001525; P:angiogenesis; IDA:UniProtKB.
48A2ALK8    913   PTN3_MOUSE Tyrosine-protein phosphatase non-r...2763e-30     126     33     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
49Q9BMN8    2200   LAR_CAEEL Tyrosine-protein phosphatase Lar-li...2841e-26     116     30     46GO:0005912; C:adherens junction; IMP:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:WormBase.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IMP:UniProtKB.::GO:0008544; P:epidermis development; IMP:WormBase.::GO:0007369; P:gastrulation; IMP:WormBase.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.
50P49446    699   PTPRE_MOUSE Receptor-type tyrosine-protein ph...2854e-28     119     32     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.::GO:0033003; P:regulation of mast cell activation; IMP:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IDA:MGI.
51P26045    913   PTN3_HUMAN Tyrosine-protein phosphatase non-r...2763e-30     126     33     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0051117; F:ATPase binding; IPI:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL.
52P23467    1997   PTPRB_HUMAN Receptor-type tyrosine-protein ph...2944e-30     126     32     47GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
53P18031    435   PTN1_HUMAN Tyrosine-protein phosphatase non-r...2785e-30     122     29     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; NAS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030100; P:regulation of endocytosis; IDA:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
54P35821    432   PTN1_MOUSE Tyrosine-protein phosphatase non-r...2785e-30     122     30     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.
55Q06180    406   PTN2_MOUSE Tyrosine-protein phosphatase non-r...2859e-30     121     32     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.
56Q15256    657   PTPRR_HUMAN Receptor-type tyrosine-protein ph...2831e-29     123     34     48GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0001701; P:in utero embryonic development; IEP:UniProtKB.
57Q4JDL3    420   PTN20_HUMAN Tyrosine-protein phosphatase non-...2761e-29     121     32     47GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
58Q12923    2485   PTN13_HUMAN Tyrosine-protein phosphatase non-...2832e-29     124     32     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
59P04157    1273   PTPRC_RAT Receptor-type tyrosine-protein phos...3090.000000000002     72     25     39GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; TAS:RGD.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0019887; F:protein kinase regulator activity; TAS:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:RGD.
GO:0042100; P:B cell proliferation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.::GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.::GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:RGD.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
60O55082    426   PTN20_MOUSE Tyrosine-protein phosphatase non-...2773e-29     120     32     45GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
61P23469    700   PTPRE_HUMAN Receptor-type tyrosine-protein ph...2852e-27     117     32     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro.
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