UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL226C

Length:

352

Number of sequences:

5887

Description:

YDL226C GCS1 SGDID:S000002385, Chr IV from 52173-51115, Genome Release 64-1-1, reverse complement, Verified ORF, "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q9FL69	483	AGD5_ARATH Probable ADP-ribosylation factor G...	110	5e-17	85.5	38	59	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005768; C:endosome; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032857; P:activation of ARF GTPase activity; IDA:TAIR.::GO:0010227; P:floral organ abscission; IMP:TAIR.
32	Q8LFN9	336	AGD13_ARATH Probable ADP-ribosylation factor ...	75	7e-17	83.6	49	67
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0009555; P:pollen development; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
33	Q15057	778	ACAP2_HUMAN Arf-GAP with coiled-coil, ANK rep...	81	1e-16	84.7	43	67
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
34	Q5FVC7	770	ACAP2_RAT Arf-GAP with coiled-coil, ANK repea...	80	1e-16	84.3	44	66
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
35	Q6ZQK5	770	ACAP2_MOUSE Arf-GAP with coiled-coil, ANK rep...	80	2e-16	84.3	44	66
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
36	Q5W7F2	827	AGD3_ARATH ADP-ribosylation factor GTPase-act...	53	2e-16	84.3	58	75	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:TAIR.
									GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0010051; P:xylem and phloem pattern formation; IMP:TAIR.
37	Q5ZK62	781	ACAP2_CHICK Arf-GAP with coiled-coil, ANK rep...	80	2e-16	84.3	44	66
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
38	Q9FIT8	828	AGD1_ARATH ADP-ribosylation factor GTPase-act...	70	2e-16	84	50	67	GO:0030139; C:endocytic vesicle; IDA:TAIR.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007010; P:cytoskeleton organization; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
39	Q6IVG4	778	ACAP2_RABIT Arf-GAP with coiled-coil, ANK rep...	81	2e-16	84	42	67
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
40	Q3UHD9	1186	AGAP2_MOUSE Arf-GAP with GTPase, ANK repeat a...	87	4e-16	83.6	44	61	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:MGI.::GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
41	Q8CGU4	1186	AGAP2_RAT Arf-GAP with GTPase, ANK repeat and...	87	4e-16	83.6	44	61	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
42	Q91VZ6	440	SMAP1_MOUSE Stromal membrane-associated prote...	62	4e-16	82.4	55	71	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IDA:MGI.::GO:0030276; F:clathrin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:MGI.
43	Q99490	1192	AGAP2_HUMAN Arf-GAP with GTPase, ANK repeat a...	87	5e-16	83.2	44	61	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.::GO:0042177; P:negative regulation of protein catabolic process; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
44	Q8VHH5	910	AGAP3_MOUSE Arf-GAP with GTPase, ANK repeat a...	68	5e-16	82.8	49	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
45	Q96P47	875	AGAP3_HUMAN Arf-GAP with GTPase, ANK repeat a...	68	6e-16	82.8	49	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
46	Q8K2H4	740	ACAP1_MOUSE Arf-GAP with coiled-coil, ANK rep...	78	0.000000000000001	81.6	41	67
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
47	A5PK26	745	ACAP1_BOVIN Arf-GAP with coiled-coil, ANK rep...	78	0.000000000000002	81.3	41	67
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
48	Q15027	740	ACAP1_HUMAN Arf-GAP with coiled-coil, ANK rep...	78	0.000000000000002	81.3	41	67
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
49	Q5F413	428	SMAP2_CHICK Stromal membrane-associated prote...	62	0.000000000000002	80.1	53	71
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
50	Q9NGC3	995	CEG1A_DROME Centaurin-gamma-1A OS=Drosophila ...	67	0.000000000000003	80.9	48	66	GO:0005634; C:nucleus; NAS:UniProtKB.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
51	Q8IYB5	467	SMAP1_HUMAN Stromal membrane-associated prote...	62	0.000000000000005	79.3	53	69	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
52	O43150	1006	ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe...	83	0.000000000000006	79.7	40	59	GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
53	Q7SIG6	958	ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe...	83	0.000000000000006	79.7	40	59	GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
54	Q6NRL1	864	AGAP1_XENLA Arf-GAP with GTPase, ANK repeat a...	72	0.000000000000007	79.3	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
55	O74345	601	UCP3_SCHPO UBA domain-containing protein 3 OS...	117	0.00000000000001	78.2	32	53	GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; TAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; ISS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.
56	Q7TN29	428	SMAP2_MOUSE Stromal membrane-associated prote...	72	0.00000000000002	77.4	44	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
57	Q5EA00	429	SMAP2_BOVIN Stromal membrane-associated prote...	62	0.00000000000002	77.4	52	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
58	Q8WU79	429	SMAP2_HUMAN Stromal membrane-associated prote...	72	0.00000000000002	77.4	44	67	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
59	Q9C6C3	776	AGD2_ARATH ADP-ribosylation factor GTPase-act...	56	0.00000000000003	77.4	52	71	GO:0005737; C:cytoplasm; IEA:InterPro.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
60	Q8BXK8	857	AGAP1_MOUSE Arf-GAP with GTPase, ANK repeat a...	72	0.00000000000006	76.6	43	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
61	Q9UPQ3	857	AGAP1_HUMAN Arf-GAP with GTPase, ANK repeat a...	72	0.00000000000007	76.3	43	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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