Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL216C
Length:
440
Number of sequences:
5887
Description:
YDL216C RRI1 SGDID:S000002375, Chr IV from 70319-68997, Genome Release 64-1-1, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9P371    435   SST2_SCHPO AMSH-like protease sst2 OS=Schizos...620.053     39.3     31     52GO:0032153; C:cell division site; IDA:PomBase.::GO:0005768; C:endosome; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:PomBase.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
62O95630    424   STABP_HUMAN STAM-binding protein OS=Homo sapi...1330.079     38.9     24     38GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
63B5RI54    344   EIF3H_SALSA Eukaryotic translation initiation...1340.079     38.9     24     47GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
64Q91WK2    352   EIF3H_MOUSE Eukaryotic translation initiation...1340.084     38.5     23     47GO:0005852; C:eukaryotic translation initiation factor 3 complex; IDA:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
65Q6P9U8    352   EIF3H_RAT Eukaryotic translation initiation f...1340.12     38.1     23     47GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.::GO:0005792; C:microsome; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
66Q56JZ5    352   EIF3H_BOVIN Eukaryotic translation initiation...1340.14     38.1     23     47GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
67Q6AXJ2    335   EI3HA_DANRE Eukaryotic translation initiation...1340.14     37.7     24     47GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IMP:ZFIN.::GO:0048882; P:lateral line development; IMP:ZFIN.::GO:0001944; P:vasculature development; IMP:ZFIN.
68Q5ZLE6    348   EIF3H_CHICK Eukaryotic translation initiation...1340.16     37.7     24     46GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
69Q5PR67    333   EI3HB_DANRE Eukaryotic translation initiation...1340.16     37.7     24     47GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0007420; P:brain development; IMP:ZFIN.::GO:0007507; P:heart development; IMP:ZFIN.
70O15372    352   EIF3H_HUMAN Eukaryotic translation initiation...1340.18     37.7     23     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005852; C:eukaryotic translation initiation factor 3 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.
71B5FY35    348   EIF3H_TAEGU Eukaryotic translation initiation...1340.21     37.4     24     46GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
72Q5PNU3    507   AMSH3_ARATH AMSH-like ubiquitin thioesterase ...420.25     37.4     38     57GO:0016021; C:integral to membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006897; P:endocytosis; IMP:TAIR.::GO:0046907; P:intracellular transport; IMP:TAIR.::GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.::GO:0044090; P:positive regulation of vacuole organization; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007033; P:vacuole organization; IMP:TAIR.
73Q54Z40    1217   MYBH_DICDI Myb-like protein H OS=Dictyosteliu...570.48     36.6     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; ISS:dictyBase.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74A0JMR6    818   MYSM1_XENLA Histone H2A deubiquitinase MYSM1 ...1300.57     36.2     23     41GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
75Q5VVJ2    828   MYSM1_HUMAN Histone H2A deubiquitinase MYSM1 ...1110.58     36.2     24     42GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q5F3F2    832   MYSM1_CHICK Histone H2A deubiquitinase MYSM1 ...1110.74     36.2     26     43GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77Q8R424    424   STABP_RAT STAM-binding protein OS=Rattus norv...420.75     35.8     36     52GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
78Q9CQ26    424   STABP_MOUSE STAM-binding protein OS=Mus muscu...420.84     35.4     36     52GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:MGI.
79Q69Z66    819   MYSM1_MOUSE Histone H2A deubiquitinase MYSM1 ...450.93     35.8     38     56GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80Q6P381    335   EIF3H_XENTR Eukaryotic translation initiation...1340.94     35.4     23     46GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
81Q5PPY6    334   EIF3H_XENLA Eukaryotic translation initiation...1341.2     35     23     46GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
82P26270    338   PSD7_DROME 26S proteasome non-ATPase regulato...1651.3     34.7     24     43GO:0030425; C:dendrite; IMP:FlyBase.::GO:0008541; C:proteasome regulatory particle, lid subcomplex; ISS:FlyBase.
GO:0004175; F:endopeptidase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.::GO:0006508; P:proteolysis; IDA:FlyBase.
83A0KIK2    254   GLO2_AERHH Hydroxyacylglutathione hydrolase O...372     33.9     43     65
GO:0004416; F:hydroxyacylglutathione hydrolase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
84O74440    324   RPN8_SCHPO 26S proteasome regulatory subunit ...1782     34.3     22     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0008541; C:proteasome regulatory particle, lid subcomplex; ISS:PomBase.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
85A8FU90    276   NADE_SHESH NH(3)-dependent NAD(+) synthetase ...472.5     33.9     34     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; IEA:InterPro.::GO:0008795; F:NAD+ synthase activity; IEA:EC.
GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
86Q54WI8    325   PSD7_DICDI 26S proteasome non-ATPase regulato...1213.1     33.5     24     43GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
87P26516    321   PSD7_MOUSE 26S proteasome non-ATPase regulato...1393.2     33.5     23     44GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
88Q3ZBD0    322   PSD7_BOVIN 26S proteasome non-ATPase regulato...1393.4     33.5     23     44GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
89P51665    324   PSD7_HUMAN 26S proteasome non-ATPase regulato...1393.7     33.5     23     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
90Q1CXF1    210   RS4B_MYXXD 30S ribosomal protein S4 B OS=Myxo...675.1     32.7     28     48GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
91P24638    423   PPAL_MOUSE Lysosomal acid phosphatase OS=Mus ...956.3     32.7     21     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043202; C:lysosomal lumen; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0003993; F:acid phosphatase activity; IDA:MGI.
GO:0007040; P:lysosome organization; IMP:MGI.::GO:0001501; P:skeletal system development; IMP:MGI.
records
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