Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL214C
Length:
699
Number of sequences:
5887
Description:
YDL214C PRR2 SGDID:S000002373, Chr IV from 76545-74446, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
841Q4WTN5    580   BUR1_ASPFU Serine/threonine-protein kinase bu...2130.000000000005     72.8     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
842Q91XS8    371   ST17B_RAT Serine/threonine-protein kinase 17B...2040.000000000005     71.6     28     50GO:0015629; C:actin cytoskeleton; IMP:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.
843A8X6H4    344   CMK1_CAEBR Calcium/calmodulin-dependent prote...2230.000000000005     71.6     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
844Q9Y2H9    1570   MAST1_HUMAN Microtubule-associated serine/thr...2180.000000000005     73.2     26     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
845Q55BN8    418   NEK2_DICDI Probable serine/threonine-protein ...2100.000000000005     72     29     52GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0007098; P:centrosome cycle; IMP:dictyBase.
846A4K2P5    487   STK4_COLGU Serine/threonine-protein kinase 4 ...2010.000000000005     72.4     26     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
847P32562    705   CDC5_YEAST Cell cycle serine/threonine-protei...2910.000000000005     72.8     25     45GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000922; C:spindle pole; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:SGD.::GO:0090306; P:spindle assembly involved in meiosis; IMP:SGD.::GO:0070194; P:synaptonemal complex disassembly; IGI:SGD.
848Q09831    566   PPK14_SCHPO Serine/threonine-protein kinase p...2850.000000000005     72.8     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0019236; P:response to pheromone; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
849Q8NU97    469   PKN2_CORGL Serine/threonine-protein kinases p...2240.000000000005     72.4     25     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
850P49137    400   MAPK2_HUMAN MAP kinase-activated protein kina...3280.000000000005     72     25     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
851Q9U1Y5    476   CHK2_CAEEL Serine/threonine-protein kinase ch...2130.000000000005     72.4     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
852Q8N568    766   DCLK2_HUMAN Serine/threonine-protein kinase D...2220.000000000005     72.8     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
853B4J3F1    762   PLK4_DROGR Serine/threonine-protein kinase PL...2050.000000000005     72.8     26     46GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
854O35831    523   CDK17_RAT Cyclin-dependent kinase 17 OS=Rattu...2010.000000000005     72.4     29     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
855Q9XF67    491   PDPK1_ARATH 3-phosphoinositide-dependent prot...2110.000000000005     72.4     26     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IGI:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045860; P:positive regulation of protein kinase activity; IDA:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
856Q8K0D0    523   CDK17_MOUSE Cyclin-dependent kinase 17 OS=Mus...2010.000000000005     72.4     29     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
857Q9UIK4    370   DAPK2_HUMAN Death-associated protein kinase 2...3130.000000000006     71.6     25     44GO:0034423; C:autophagic vacuole lumen; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:ProtInc.::GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0043276; P:anoikis; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
858B2MVY4    303   CDK4_SHEEP Cyclin-dependent kinase 4 OS=Ovis ...3080.000000000006     70.9     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
859Q32KY4    303   CDK4_BOVIN Cyclin-dependent kinase 4 OS=Bos t...3080.000000000006     70.9     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
860Q6FKD4    302   PHO85_CANGA Negative regulator of the PHO sys...1850.000000000006     70.5     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
861Q53N72    498   MPK15_ORYSJ Mitogen-activated protein kinase ...2190.000000000006     72     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
862Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...2970.000000000006     71.6     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
863Q9D411    328   TSSK4_MOUSE Testis-specific serine/threonine-...2120.000000000006     70.9     26     45GO:0001669; C:acrosomal vesicle; TAS:UniProtKB.::GO:0019861; C:flagellum; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
864B4KYX8    778   PLK4_DROMO Serine/threonine-protein kinase PL...2040.000000000006     72.8     25     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
865P34722    704   KPC1_CAEEL Protein kinase C-like 1 OS=Caenorh...2430.000000000006     72.4     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.
866Q6AX33    1482   MAST3_XENLA Microtubule-associated serine/thr...2030.000000000006     73.2     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
867P41892    1062   CDC7_SCHPO Cell division control protein 7 OS...1870.000000000006     72.8     30     50GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IGI:PomBase.
868Q9U9Y8    634   NLK_CAEEL Serine/threonine kinase NLK OS=Caen...3130.000000000006     72.4     23     43GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001714; P:endodermal cell fate specification; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0042694; P:muscle cell fate specification; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:WormBase.
869Q2MHE4    390   HT1_ARATH Serine/threonine-protein kinase HT1...2010.000000000006     71.6     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010119; P:regulation of stomatal movement; IMP:TAIR.
870P00546    298   CDK1_YEAST Cyclin-dependent kinase 1 OS=Sacch...2140.000000000007     70.5     29     47GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:SGD.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:SGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:SGD.::GO:0010571; P:positive regulation of DNA replication involved in S phase; IMP:SGD.::GO:0051446; P:positive regulation of meiotic cell cycle; IDA:SGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:SGD.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:SGD.::GO:0010898; P:positive regulation of triglyceride catabolic process; IMP:SGD.::GO:0010568; P:regulation of budding cell apical bud growth; IMP:SGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:SGD.::GO:0010570; P:regulation of filamentous growth; IMP:SGD.
871P59241    397   AURKA_RAT Aurora kinase A OS=Rattus norvegicu...3590.000000000007     71.6     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
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