Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL214C
Length:
699
Number of sequences:
5887
Description:
YDL214C PRR2 SGDID:S000002373, Chr IV from 76545-74446, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor; mutant has increased aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q03957    528   CTK1_YEAST CTD kinase subunit alpha OS=Saccha...1995e-16     85.5     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:SGD.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IDA:SGD.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0045903; P:positive regulation of translational fidelity; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
332Q7L7X3    1001   TAOK1_HUMAN Serine/threonine-protein kinase T...2035e-16     86.3     30     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
333P50750    372   CDK9_HUMAN Cyclin-dependent kinase 9 OS=Homo ...2065e-16     84     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008023; C:transcription elongation factor complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.::GO:0031056; P:regulation of histone modification; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0043111; P:replication fork arrest; IDA:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.::GO:0016032; P:viral reproduction; TAS:Reactome.
334Q12236    1081   PKH2_YEAST Serine/threonine-protein kinase PK...2595e-16     86.3     26     46GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
335Q9WTK7    436   STK11_MOUSE Serine/threonine-protein kinase S...2995e-16     84.7     26     45GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030275; F:LRR domain binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0051645; P:Golgi localization; IMP:MGI.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IGI:MGI.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051896; P:regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:MGI.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0007286; P:spermatid development; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI.::GO:0001944; P:vasculature development; IMP:UniProtKB.
336Q8RXG3    348   M2K5_ARATH Mitogen-activated protein kinase k...2095e-16     83.6     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009814; P:defense response, incompatible interaction; IMP:TAIR.::GO:0010227; P:floral organ abscission; IMP:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR.
337Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...2065e-16     85.9     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
338Q54QI2    941   Y9877_DICDI Serine/threonine-protein kinase D...2026e-16     85.9     28     50GO:0016020; C:membrane; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
339O88643    545   PAK1_MOUSE Serine/threonine-protein kinase PA...2276e-16     85.1     26     51GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042060; P:wound healing; ISS:UniProtKB.
340Q5ZJH6    468   ULK3_CHICK Serine/threonine-protein kinase UL...1726e-16     84.7     31     55GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
341Q09170    460   CDS1_SCHPO Serine/threonine-protein kinase cd...3026e-16     84.7     27     46GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; TAS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
342Q2VWQ3    642   STE20_PENMA Serine/threonine-protein kinase p...2096e-16     85.1     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
343Q5N942    360   SAPK4_ORYSJ Serine/threonine-protein kinase S...2066e-16     83.6     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
344Q80YP0    303   CDK3_MOUSE Cyclin-dependent kinase 3 OS=Mus m...2887e-16     82.8     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
345Q39030    471   KPK2_ARATH Serine/threonine-protein kinase At...2377e-16     84.7     26     53GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
346O14328    474   KSP1_SCHPO Serine/threonine-protein kinase ks...2397e-16     84.7     28     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
347Q96VK3    544   BUR1_EMENI Serine/threonine-protein kinase bu...2107e-16     84.7     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
348P35465    544   PAK1_RAT Serine/threonine-protein kinase PAK ...1997e-16     84.7     27     52GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0014704; C:intercalated disc; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0030018; C:Z disc; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0033554; P:cellular response to stress; IDA:RGD.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:RGD.::GO:0042060; P:wound healing; ISS:UniProtKB.
349E1BB50    1264   CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos...3207e-16     85.9     24     44GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
350Q13153    545   PAK1_HUMAN Serine/threonine-protein kinase PA...1997e-16     84.7     27     52GO:0030424; C:axon; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0014704; C:intercalated disc; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048754; P:branching morphogenesis of a tube; IMP:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0042060; P:wound healing; IMP:UniProtKB.
351Q08E52    544   PAK1_BOVIN Serine/threonine-protein kinase PA...2277e-16     84.7     26     51GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042060; P:wound healing; ISS:UniProtKB.
352Q84TI6    470   CDKE1_ARATH Cyclin-dependent kinase E-1 OS=Ar...2087e-16     84.3     26     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
353Q9NYV4    1490   CDK12_HUMAN Cyclin-dependent kinase 12 OS=Hom...3277e-16     85.9     24     44GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IMP:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.::GO:0043405; P:regulation of MAP kinase activity; IMP:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
354Q15746    1914   MYLK_HUMAN Myosin light chain kinase, smooth ...2648e-16     85.9     27     48GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IDA:UniProtKB.
GO:0060414; P:aorta smooth muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0032060; P:bleb assembly; IMP:UniProtKB.::GO:0071476; P:cellular hypotonic response; IDA:UniProtKB.::GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0090303; P:positive regulation of wound healing; IDA:UniProtKB.::GO:0014820; P:tonic smooth muscle contraction; ISS:UniProtKB.
355Q62829    544   PAK3_RAT Serine/threonine-protein kinase PAK ...2719e-16     84.3     24     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051020; F:GTPase binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.
356Q4WHP3    815   STE20_ASPFU Serine/threonine-protein kinase s...1999e-16     85.1     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
357O76039    1030   CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS...2069e-16     85.1     28     49GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
358P43450    298   CDK2_CARAU Cyclin-dependent kinase 2 OS=Caras...2020.000000000000001     82     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
359Q69ZA1    1511   CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus...2430.000000000000001     85.1     28     45GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.
360Q3MJK5    1484   CDK12_RAT Cyclin-dependent kinase 12 OS=Rattu...3260.000000000000001     85.1     23     44GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IMP:UniProtKB.
361Q4KM47    358   CDK10_RAT Cyclin-dependent kinase 10 OS=Rattu...1920.000000000000001     82.4     28     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
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