UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL205C

Length:

327

Number of sequences:

5887

Description:

YDL205C HEM3 SGDID:S000002364, Chr IV from 93745-92762, Genome Release 64-1-1, reverse complement, Verified ORF, "Porphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in heme biosynthesis; localizes to the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p, but not by levels of heme"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
421	A4WN24	297	HEM3_PYRAR Probable porphobilinogen deaminase...	253	4e-37	140	33	55
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
422	P30527	183	HEM3_YERIN Porphobilinogen deaminase OS=Yersi...	189	4e-37	136	42	58
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
423	Q9ABZ8	322	HEM3_CAUCR Porphobilinogen deaminase OS=Caulo...	323	9e-37	139	33	47
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
424	B8GXG1	322	HEM3_CAUCN Porphobilinogen deaminase OS=Caulo...	323	9e-37	139	33	47
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
425	Q8ZYW7	297	HEM3_PYRAE Probable porphobilinogen deaminase...	253	1e-36	139	32	55
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
426	O26960	289	HEM3_METTH Probable porphobilinogen deaminase...	271	1e-36	138	34	55
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
427	B3CUP9	298	HEM3_ORITI Porphobilinogen deaminase OS=Orien...	269	1e-36	138	36	53
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
428	A4QB59	302	HEM3_CORGB Porphobilinogen deaminase OS=Coryn...	317	2e-36	138	32	53
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
429	Q491Z6	300	HEM3_BLOPB Porphobilinogen deaminase OS=Bloch...	310	3e-36	137	31	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
430	Q8FSF7	299	HEM3_COREF Porphobilinogen deaminase OS=11189...	317	3e-36	137	32	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
431	B0T287	318	HEM3_CAUSK Porphobilinogen deaminase OS=Caulo...	283	3e-36	138	33	49
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
432	Q8NT90	302	HEM3_CORGL Porphobilinogen deaminase OS=LMG 3...	317	3e-36	137	32	53
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
433	A2BL26	303	HEM3_HYPBU Probable porphobilinogen deaminase...	283	6e-36	137	34	52
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
434	A1RQK2	301	HEM3_PYRIL Probable porphobilinogen deaminase...	261	3e-35	135	33	54
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
435	Q9KY00	313	HEM32_STRCO Porphobilinogen deaminase 2 OS=St...	327	3e-35	135	31	50
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
436	C3PKG2	296	HEM3_CORA7 Porphobilinogen deaminase OS=(Cory...	313	8e-35	134	31	52
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
437	A0QLI0	315	HEM3_MYCA1 Porphobilinogen deaminase OS=Mycob...	286	9e-35	134	33	50
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
438	Q73SS0	315	HEM3_MYCPA Porphobilinogen deaminase OS=Mycob...	286	9e-35	134	33	50
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
439	Q7VRM4	311	HEM3_BLOFL Porphobilinogen deaminase OS=Bloch...	311	1e-34	133	32	49
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
440	Q82E76	324	HEM31_STRAW Porphobilinogen deaminase 1 OS=St...	329	1e-34	134	30	48
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
441	B2HRJ2	314	HEM3_MYCMM Porphobilinogen deaminase OS=Mycob...	286	1e-34	133	33	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
442	P64336	309	HEM3_MYCTU Porphobilinogen deaminase OS=Mycob...	285	2e-34	133	32	51	GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0040007; P:growth; IMP:MTBBASE.::GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
443	A5TZP0	309	HEM3_MYCTA Porphobilinogen deaminase OS=Mycob...	285	2e-34	133	32	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
444	C1AKJ0	309	HEM3_MYCBT Porphobilinogen deaminase OS=Mycob...	285	2e-34	133	32	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
445	A1KFY6	309	HEM3_MYCBP Porphobilinogen deaminase OS=Mycob...	285	2e-34	133	32	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
446	P64337	309	HEM3_MYCBO Porphobilinogen deaminase OS=Mycob...	285	2e-34	133	32	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
447	Q5YP70	346	HEM3_NOCFA Porphobilinogen deaminase OS=Nocar...	324	3e-34	133	32	48
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
448	A1T3D3	312	HEM3_MYCVP Porphobilinogen deaminase OS=Mycob...	327	5e-34	132	30	47
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
449	A0PW29	314	HEM3_MYCUA Porphobilinogen deaminase OS=Mycob...	286	1e-33	131	33	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
450	Q1GP41	315	HEM3_SPHAL Porphobilinogen deaminase OS=(Sphi...	228	1e-33	130	36	54
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
451	A8AAB4	304	HEM3_IGNH4 Probable porphobilinogen deaminase...	284	3e-33	129	33	51
									GO:0004418; F:hydroxymethylbilane synthase activity; IEA:EC.
									GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.

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