Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL192W
Length:
181
Number of sequences:
5887
Description:
YDL192W ARF1 SGDID:S000002351, Chr IV from 116321-116866, Genome Release 64-1-1, Verified ORF, "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q55E31    260   RB32B_DICDI Ras-related protein Rab-32B OS=Di...1760.0002     43.9     23     46
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
632Q08CX1    722   RASEF_XENTR Ras and EF-hand domain-containing...920.0002     44.3     29     50GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
633Q5R6B6    212   RAB2A_PONAB Ras-related protein Rab-2A OS=Pon...1580.0002     43.9     23     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
634Q4R4X6    212   RAB2A_MACFA Ras-related protein Rab-2A OS=Mac...1580.0002     43.9     23     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
635P61019    212   RAB2A_HUMAN Ras-related protein Rab-2A OS=Hom...1580.0002     43.9     23     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
636P61105    212   RAB2A_CANFA Ras-related protein Rab-2A OS=Can...1580.0002     43.9     23     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
637Q58DS9    216   RAB5C_BOVIN Ras-related protein Rab-5C OS=Bos...1240.0002     43.9     27     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
638O95837    355   GNA14_HUMAN Guanine nucleotide-binding protei...970.0002     44.3     27     51GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IBA:RefGenome.
GO:0060158; P:activation of phospholipase C activity by dopamine receptor signaling pathway; IBA:RefGenome.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IBA:RefGenome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0006471; P:protein ADP-ribosylation; IEA:InterPro.
639Q9Y5M8    271   SRPRB_HUMAN Signal recognition particle recep...1330.0002     43.9     29     50GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.::GO:0006412; P:translation; TAS:Reactome.
640Q7Z6P3    723   RAB44_HUMAN Ras-related protein Rab-44 OS=Hom...1370.0002     44.3     25     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
641P10825    354   GNAO_XENLA Guanine nucleotide-binding protein...1550.0002     43.9     23     37
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
642P27584    407   GPA1_SCHPO Guanine nucleotide-binding protein...1400.0002     44.3     23     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0005834; C:heterotrimeric G-protein complex; NAS:PomBase.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; ISS:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; ISS:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007189; P:activation of adenylate cyclase activity by G-protein signaling pathway; ISS:RefGenome.::GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0060240; P:negative regulation of signal transduction involved in conjugation with cellular fusion; NAS:PomBase.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
643Q0WQN4    229   RAA6B_ARATH Ras-related protein RABA6b OS=Ara...850.0002     43.9     28     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
644Q5R7L7    216   RAB5C_PONAB Ras-related protein Rab-5C OS=Pon...1240.0002     43.9     27     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
645P51148    216   RAB5C_HUMAN Ras-related protein Rab-5C OS=Hom...1240.0002     43.9     27     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
646Q01111    218   YPT3_NICPL Ras-related protein YPT3 OS=Nicoti...810.0002     43.9     30     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
647P38402    355   GNAI2_CAVPO Guanine nucleotide-binding protei...990.0002     43.9     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; ISS:UniProtKB.
648P08752    355   GNAI2_MOUSE Guanine nucleotide-binding protei...990.0002     43.9     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.::GO:0030496; C:midbody; ISS:UniProtKB.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IBA:RefGenome.
GO:0001973; P:adenosine receptor signaling pathway; IBA:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; ISS:UniProtKB.::GO:0008283; P:cell proliferation; IPI:MGI.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IMP:MGI.::GO:0007214; P:gamma-aminobutyric acid signaling pathway; IBA:RefGenome.::GO:0007193; P:inhibition of adenylate cyclase activity by G-protein signaling pathway; IMP:MGI.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IBA:RefGenome.
649Q4R592    355   GNAI2_MACFA Guanine nucleotide-binding protei...990.0003     43.9     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
650P04899    355   GNAI2_HUMAN Guanine nucleotide-binding protei...990.0003     43.9     25     46GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.::GO:0030496; C:midbody; IDA:UniProtKB.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0001973; P:adenosine receptor signaling pathway; IBA:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IMP:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007214; P:gamma-aminobutyric acid signaling pathway; IBA:RefGenome.::GO:0007193; P:inhibition of adenylate cyclase activity by G-protein signaling pathway; TAS:Reactome.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IBA:RefGenome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007584; P:response to nutrient; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome.
651P36864    205   YPTV5_VOLCA GTP-binding protein yptV5 OS=Volv...1580.0003     43.5     25     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
652Q54VG1    354   GPA12_DICDI Guanine nucleotide-binding protei...970.0003     43.9     30     47GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IBA:RefGenome.
GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IBA:RefGenome.
653P50147    355   GNAI2_CHICK Guanine nucleotide-binding protei...990.0003     43.9     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.::GO:0030496; C:midbody; ISS:UniProtKB.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IBA:RefGenome.
GO:0001973; P:adenosine receptor signaling pathway; IBA:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007214; P:gamma-aminobutyric acid signaling pathway; IBA:RefGenome.::GO:0007193; P:inhibition of adenylate cyclase activity by G-protein signaling pathway; IBA:RefGenome.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IBA:RefGenome.
654Q61820    216   RANT_MOUSE GTP-binding nuclear protein Ran, t...860.0003     43.5     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
655P38400    355   GNAI2_CANFA Guanine nucleotide-binding protei...990.0003     43.9     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005834; C:heterotrimeric G-protein complex; ISS:RefGenome.::GO:0030496; C:midbody; ISS:UniProtKB.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; ISS:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; ISS:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; ISS:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; ISS:RefGenome.
GO:0001973; P:adenosine receptor signaling pathway; ISS:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007214; P:gamma-aminobutyric acid signaling pathway; ISS:RefGenome.::GO:0007193; P:inhibition of adenylate cyclase activity by G-protein signaling pathway; ISS:RefGenome.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; ISS:RefGenome.
656Q9BIG5    359   GPA4_CAEEL Guanine nucleotide-binding protein...970.0003     43.9     26     46GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IBA:RefGenome.
GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; IBA:RefGenome.
657P04897    355   GNAI2_RAT Guanine nucleotide-binding protein ...990.0003     43.9     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005834; C:heterotrimeric G-protein complex; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.::GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IBA:RefGenome.
GO:0000186; P:activation of MAPKK activity; IMP:RGD.::GO:0001973; P:adenosine receptor signaling pathway; IDA:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007214; P:gamma-aminobutyric acid signaling pathway; IDA:RGD.::GO:0007193; P:inhibition of adenylate cyclase activity by G-protein signaling pathway; IBA:RefGenome.::GO:0007243; P:intracellular protein kinase cascade; IMP:RGD.::GO:0051927; P:negative regulation of calcium ion transport via voltage-gated calcium channel activity; IDA:RGD.::GO:0050805; P:negative regulation of synaptic transmission; IDA:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.
658Q550H6    224   RB11C_DICDI Ras-related protein Rab-11C OS=Di...800.0003     43.5     31     49GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
659Q9WYA4    450   MNME_THEMA tRNA modification GTPase MnmE OS=T...1730.0003     43.9     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
660P92963    211   RAB1C_ARATH Ras-related protein RABB1c OS=Ara...850.0003     43.5     28     46GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
661B1L9N6    450   MNME_THESQ tRNA modification GTPase MnmE OS=T...1730.0003     43.9     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
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