Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL182W
Length:
428
Number of sequences:
5887
Description:
YDL182W LYS20 SGDID:S000002341, Chr IV from 133437-134723, Genome Release 64-1-1, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511B8ESV2    346   HOA_METSB 4-hydroxy-2-oxovalerate aldolase OS...2540.012     41.2     24     39
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
512Q88P28    557   LEU1_PSEPK 2-isopropylmalate synthase OS=Pseu...3160.013     41.6     23     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
513B2HGH1    344   HOA1_MYCMM 4-hydroxy-2-oxovalerate aldolase 1...2360.014     41.2     23     38
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
514A1TDB7    337   HOA2_MYCVP 4-hydroxy-2-oxovalerate aldolase 2...2370.014     40.8     24     36
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
515Q48LY5    556   LEU1_PSE14 2-isopropylmalate synthase OS=Pseu...4300.016     41.2     21     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
516Q4K6V7    559   LEU1_PSEF5 2-isopropylmalate synthase OS=Pseu...3160.016     41.2     23     37
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
517A4VNV6    556   LEU1_PSEU5 2-isopropylmalate synthase OS=Pseu...3450.017     41.2     21     36
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
518Q82BV3    573   LEU1_STRAW 2-isopropylmalate synthase OS=Stre...1050.017     41.2     28     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
519Q5R9E1    325   HMGCL_PONAB Hydroxymethylglutaryl-CoA lyase, ...2380.021     40.4     21     42GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
520Q03030    591   DCOA_SALTY Oxaloacetate decarboxylase alpha c...1020.021     40.8     25     43
GO:0008948; F:oxaloacetate decarboxylase activity; IEA:EC.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
521P35914    325   HMGCL_HUMAN Hydroxymethylglutaryl-CoA lyase, ...770.024     40     27     51GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.::GO:0005777; C:peroxisome; IDA:UniProtKB.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0046951; P:ketone body biosynthetic process; IDA:UniProtKB.::GO:0006552; P:leucine catabolic process; NAS:UniProtKB.
522P51018    352   HOA1_PSEP1 4-hydroxy-2-oxovalerate aldolase 1...2410.027     40     24     40
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
523Q120N9    349   HOA_POLSJ 4-hydroxy-2-oxovalerate aldolase OS...2550.027     40     24     40
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
524B5Z2Q7    337   HOA_ECO5E 4-hydroxy-2-oxovalerate aldolase OS...2490.027     40     24     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
525Q0VLR3    559   LEU1_ALCBS 2-isopropylmalate synthase OS=Alca...3510.028     40.4     24     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
526Q8X5J8    337   HOA_ECO57 4-hydroxy-2-oxovalerate aldolase OS...2490.029     40     24     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
527O31046    573   LEU1_STRCO 2-isopropylmalate synthase OS=Stre...1050.031     40.4     29     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
528Q5YVA5    580   LEU1_NOCFA 2-isopropylmalate synthase OS=Noca...1330.034     40     29     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
529Q9S152    343   HOA1_COMTE 4-hydroxy-2-oxovalerate aldolase 1...2510.039     39.7     23     40
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
530Q3Z554    337   HOA_SHISS 4-hydroxy-2-oxovalerate aldolase OS...2360.042     39.7     23     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
531Q70AC7    505   5S_PROFR Methylmalonyl-CoA carboxyltransferas...1060.042     39.7     25     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047154; F:methylmalonyl-CoA carboxytransferase activity; IEA:EC.
532C7QJN7    573   LEU1_CATAD 2-isopropylmalate synthase OS=1021...1330.043     39.7     26     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
533A0JX36    579   LEU1_ARTS2 2-isopropylmalate synthase OS=Arth...1050.043     39.7     30     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
534A1T2N6    338   HOA1_MYCVP 4-hydroxy-2-oxovalerate aldolase 1...2720.051     39.3     25     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
535A1K6Y4    342   HOA2_AZOSB 4-hydroxy-2-oxovalerate aldolase 2...2780.053     39.3     24     43
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
536A1K893    346   HOA3_AZOSB 4-hydroxy-2-oxovalerate aldolase 3...2780.053     39.3     24     43
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
537B1LIN7    337   HOA_ECOSM 4-hydroxy-2-oxovalerate aldolase OS...2680.053     39.3     23     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
538B7NK03    337   HOA_ECO7I 4-hydroxy-2-oxovalerate aldolase OS...2680.053     39.3     23     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
539P51019    345   HOA2_PSEPU 4-hydroxy-2-oxovalerate aldolase O...2440.057     39.3     24     39
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
540B0RCQ8    588   LEU1_CLAMS 2-isopropylmalate synthase OS=9667...1050.064     39.3     27     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
541A5CRB9    588   LEU1_CLAM3 2-isopropylmalate synthase OS=Clav...1050.066     39.3     27     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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