Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL182W
Length:
428
Number of sequences:
5887
Description:
YDL182W LYS20 SGDID:S000002341, Chr IV from 133437-134723, Genome Release 64-1-1, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481B2AHM5    569   LEU1_CUPTR 2-isopropylmalate synthase OS=(str...3560.0004     46.2     21     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
482O59736    584   LEU1_SCHPO 2-isopropylmalate synthase OS=Schi...1620.0004     46.2     27     38GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0003852; F:2-isopropylmalate synthase activity; ISS:PomBase.
GO:0009098; P:leucine biosynthetic process; IMP:PomBase.
483Q8TB92    370   HMGC2_HUMAN Probable 3-hydroxymethyl-3-methyl...2480.0005     45.8     23     43
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
484P35915    298   HMGCL_CHICK Hydroxymethylglutaryl-CoA lyase O...2340.0006     45.1     21     41GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
485B9JML6    338   HOA_AGRRK 4-hydroxy-2-oxovalerate aldolase OS...2440.0006     45.4     23     39
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
486Q8FU05    581   LEU1_COREF 2-isopropylmalate synthase OS=1118...1150.0006     45.8     30     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
487Q9UUE1    1185   PYC_SCHPO Pyruvate carboxylase OS=Schizosacch...1340.001     45.1     25     48GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; ISS:PomBase.
GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006094; P:gluconeogenesis; ISS:PomBase.
488A8L551    565   LEU1_FRASN 2-isopropylmalate synthase OS=Fran...3120.001     44.7     22     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
489P97519    325   HMGCL_RAT Hydroxymethylglutaryl-CoA lyase, mi...2380.002     43.9     21     42GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IPI:RGD.::GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.
GO:0006637; P:acyl-CoA metabolic process; IDA:RGD.::GO:0046951; P:ketone body biosynthetic process; IDA:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.
490C1DE40    557   LEU1_AZOVD 2-isopropylmalate synthase OS=Azot...3160.002     44.3     22     37
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
491Q1MDH6    560   LEU1_RHIL3 2-isopropylmalate synthase OS=Rhiz...3860.002     44.3     24     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
492P38060    325   HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, ...2360.002     43.5     21     41GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.
GO:0009790; P:embryo development; IMP:MGI.::GO:0007005; P:mitochondrion organization; IMP:MGI.
493A4XY24    556   LEU1_PSEMY 2-isopropylmalate synthase OS=Pseu...3500.002     43.9     22     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
494B4EFI7    347   HOA2_BURCJ 4-hydroxy-2-oxovalerate aldolase 2...2450.002     43.5     26     40
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
495B1JDI2    557   LEU1_PSEPW 2-isopropylmalate synthase OS=Pseu...3170.003     43.5     23     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
496Q1I5K2    557   LEU1_PSEE4 2-isopropylmalate synthase OS=Pseu...3210.003     43.5     22     36
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
497Q00852    352   NIFVO_CLOPA Homocitrate synthase, omega subun...620.003     43.1     35     53
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
498A0PVE6    566   LEU1_MYCUA 2-isopropylmalate synthase OS=Myco...1170.003     43.5     28     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
499A1R6V4    579   LEU1_ARTAT 2-isopropylmalate synthase OS=Arth...1050.003     43.1     31     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
500A6V0X2    556   LEU1_PSEA7 2-isopropylmalate synthase OS=Pseu...3130.004     43.1     22     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
501A8LAA1    377   HOA1_FRASN 4-hydroxy-2-oxovalerate aldolase 1...2680.005     42.7     23     38
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
502C3K1K7    559   LEU1_PSEFS 2-isopropylmalate synthase OS=Pseu...1590.005     42.7     25     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
503O27179    568   PYCB_METTH Pyruvate carboxylase subunit B OS=...780.006     42.7     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:InterPro.
504B0KRD9    557   LEU1_PSEPG 2-isopropylmalate synthase OS=Pseu...3190.007     42.4     24     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
505A9HW07    568   LEU1_BORPD 2-isopropylmalate synthase OS=Bord...2230.007     42.4     24     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
506Q12166    604   LEU9_YEAST 2-isopropylmalate synthase 2, mito...3180.008     42.4     22     36GO:0005739; C:mitochondrion; IDA:SGD.
GO:0003852; F:2-isopropylmalate synthase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009098; P:leucine biosynthetic process; IGI:SGD.
507B8H8Q9    579   LEU1_ARTCA 2-isopropylmalate synthase OS=JCM ...1050.008     42     30     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
508D2ATJ4    579   LEU1_STRRD 2-isopropylmalate synthase OS=NI 9...1210.01     42     30     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
509A5VZB6    557   LEU1_PSEP1 2-isopropylmalate synthase OS=Pseu...3160.01     42     23     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
510Q8HXZ6    325   HMGCL_MACFA Hydroxymethylglutaryl-CoA lyase, ...770.012     41.2     27     51GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
511B8ESV2    346   HOA_METSB 4-hydroxy-2-oxovalerate aldolase OS...2540.012     41.2     24     39
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
records
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