Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL182W
Length:
428
Number of sequences:
5887
Description:
YDL182W LYS20 SGDID:S000002341, Chr IV from 133437-134723, Genome Release 64-1-1, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451A1KBD3    572   LEU1_AZOSB 2-isopropylmalate synthase OS=Azoa...4050.000008     51.6     22     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
452B8G187    333   HOA_DESHD 4-hydroxy-2-oxovalerate aldolase OS...1570.000008     51.2     27     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
453A8H4E9    340   HOA_SHEPA 4-hydroxy-2-oxovalerate aldolase OS...3220.000008     51.2     26     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
454B0TTS9    340   HOA_SHEHH 4-hydroxy-2-oxovalerate aldolase OS...890.00001     50.8     37     51
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
455Q9KWU4    1148   PYC_BACSU Pyruvate carboxylase OS=Bacillus su...810.00001     51.2     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:InterPro.
456Q0PHX9    341   HOA_SPIAU 4-hydroxy-2-oxovalerate aldolase OS...870.00001     50.4     37     49
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
457B2SXZ9    572   LEU1_BURPP 2-isopropylmalate synthase OS=Burk...3420.00002     50.8     23     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
458B1J6Y1    339   HOA2_PSEPW 4-hydroxy-2-oxovalerate aldolase 2...2410.00002     50.1     24     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
459B1VRH5    340   HOA_STRGG 4-hydroxy-2-oxovalerate aldolase OS...1450.00002     49.7     31     43
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
460Q4F8H9    347   HOA1_PSEPS 4-hydroxy-2-oxovalerate aldolase 1...1550.00003     49.7     30     48
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
461B7GT76    638   LEU1_BIFLS 2-isopropylmalate synthase OS=/ JC...3360.00003     50.1     24     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
462Q3K7C3    559   LEU1_PSEPF 2-isopropylmalate synthase OS=Pseu...3390.00004     49.3     24     37
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
463Q8XSZ5    576   LEU12_RALSO 2-isopropylmalate synthase 2 OS=R...3420.00005     49.3     23     37
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
464O81027    468   HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, ...770.00005     48.9     30     55GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
465A7HP03    563   LEU1_PARL1 2-isopropylmalate synthase OS=Parv...3420.00006     48.9     23     37
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
466A0PR18    344   HOA1_MYCUA 4-hydroxy-2-oxovalerate aldolase 1...2530.00007     48.1     24     40
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
467Q51983    350   HOA2_PSEP1 4-hydroxy-2-oxovalerate aldolase 2...2810.00007     48.1     25     39
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
468Q29448    325   HMGCL_BOVIN Hydroxymethylglutaryl-CoA lyase, ...2440.00007     48.1     21     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.
469A8WG57    335   HMGC2_DANRE Probable 3-hydroxymethyl-3-methyl...2370.00008     48.1     24     43
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
470B2UJY9    570   LEU1_RALPJ 2-isopropylmalate synthase OS=Rals...3480.00008     48.5     23     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
471Q58628    567   PYCB_METJA Pyruvate carboxylase subunit B OS=...740.0001     48.1     28     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:InterPro.
472P42455    616   LEU1_CORGL 2-isopropylmalate synthase OS=LMG ...3100.0001     48.1     23     35
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
473Q8JZS7    343   HMGC2_MOUSE Probable 3-hydroxymethyl-3-methyl...2550.0001     47.4     23     43
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
474Q47B13    353   HOA3_DECAR 4-hydroxy-2-oxovalerate aldolase 3...2420.0002     47.4     27     40
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
475P13703    301   HMGCL_PSEMV Hydroxymethylglutaryl-CoA lyase O...790.0003     46.2     33     52
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
476Q47RM9    568   LEU1_THEFY 2-isopropylmalate synthase OS=Ther...3160.0003     47     24     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
477A8LEP8    336   HOA2_FRASN 4-hydroxy-2-oxovalerate aldolase 2...2430.0003     46.2     24     41
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
478Q9HXK5    556   LEU1_PSEAE 2-isopropylmalate synthase OS=1222...4250.0003     46.6     21     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
479Q24PE3    557   LEU1_DESHY 2-isopropylmalate synthase OS=Desu...2830.0003     46.6     22     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
480A4QAP0    616   LEU1_CORGB 2-isopropylmalate synthase OS=Cory...3100.0004     46.2     23     35
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
481B2AHM5    569   LEU1_CUPTR 2-isopropylmalate synthase OS=(str...3560.0004     46.2     21     38
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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