Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL182W
Length:
428
Number of sequences:
5887
Description:
YDL182W LYS20 SGDID:S000002341, Chr IV from 133437-134723, Genome Release 64-1-1, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P48570    428   HOSC_YEAST Homocitrate synthase, cytosolic is...4280     879     100     100GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004410; F:homocitrate synthase activity; IDA:SGD.
GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IGI:SGD.
2Q12122    440   HOSM_YEAST Homocitrate synthase, mitochondria...4190     792     92     95GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IMP:SGD.
3Q12726    446   HOSM_YARLI Homocitrate synthase, mitochondria...4250     734     84     90GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
4Q9Y823    418   HOSM_SCHPO Homocitrate synthase, mitochondria...3890     653     78     89GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0004410; F:homocitrate synthase activity; IMP:PomBase.
GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IMP:PomBase.
5O94225    474   HOSM_PENCW Homocitrate synthase, mitochondria...3910     646     78     88GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
6O87198    376   HOSC_THET2 Homocitrate synthase OS=Thermus th...3751e-142     419     54     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.
7Q971S5    460   HOSA_SULTO Putative homocitrate synthase OS=S...3852e-67     228     38     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
8Q58595    518   LEU1_METJA 2-isopropylmalate synthase OS=JCM ...3826e-65     223     36     54
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
9Q8TYB1    499   LEU1_METKA Probable 2-isopropylmalate synthas...3859e-65     221     34     54
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
10C3NDV7    461   HOSA_SULIY Putative homocitrate synthase OS=S...3597e-63     216     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
11C3NHU6    461   HOSA_SULIN Putative homocitrate synthase OS=S...3597e-63     216     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
12C3MYM1    461   HOSA_SULIM Putative homocitrate synthase OS=S...3597e-63     216     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
13C4KGW9    461   HOSA_SULIK Putative homocitrate synthase OS=S...3597e-63     216     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
14C3N5A3    461   HOSA_SULIA Putative homocitrate synthase OS=S...3597e-63     216     36     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
15C3MPM7    461   HOSA_SULIL Putative homocitrate synthase OS=S...3594e-62     214     35     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
16Q58787    491   CIMA_METJA (R)-citramalate synthase CimA OS=J...3535e-60     209     34     57
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
17Q9V1J1    361   HOSA_PYRAB Putative homocitrate synthase OS=P...3333e-58     201     33     55
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0046912; F:transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
18O30020    503   LEU1_ARCFU Probable 2-isopropylmalate synthas...3674e-58     204     34     55
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
19Q57926    406   AKSA_METJA Probable homocitrate synthase AksA...3675e-58     201     33     53
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
20Q8RCF9    384   LEU12_THETN 2-isopropylmalate synthase 2 OS=1...3541e-57     200     32     53
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.::GO:0004410; F:homocitrate synthase activity; IEA:InterPro.
GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
21Q97ZE0    461   HOSA_SULSO Putative homocitrate synthase OS=P...3595e-57     200     35     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
22O27525    505   LEU1_METTH Probable 2-isopropylmalate synthas...3691e-55     197     33     50
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
23O27667    391   AKSA_METTH Putative homocitrate synthase AksA...3521e-55     194     35     53
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
24O59390    361   HOSA_PYRHO Putative homocitrate synthase OS=N...3463e-55     192     33     54
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
25O29305    489   CIMA_ARCFU Putative (R)-citramalate synthase ...3917e-55     195     32     54
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
26Q8THA5    515   LEU1_METAC Probable 2-isopropylmalate synthas...3732e-53     192     29     53
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
27Q8TW28    397   AKSA_METKA Putative homocitrate synthase AksA...3845e-53     187     32     51
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
28P58968    516   LEU1_METMA Probable 2-isopropylmalate synthas...3646e-53     190     30     53
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
29B8GEI1    500   CIMA_METPE Putative (R)-citramalate synthase ...3873e-51     185     32     49
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
30O26819    496   CIMA_METTH Putative (R)-citramalate synthase ...4103e-50     182     31     49
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
31A8AB61    399   LEU1_IGNH4 Probable 2-isopropylmalate synthas...3567e-50     179     33     50
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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