Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL154W
Length:
901
Number of sequences:
5887
Description:
YDL154W MSH5 SGDID:S000002313, Chr IV from 178334-181039, Genome Release 64-1-1, Verified ORF, "Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181B9EBI4    846   MUTS_MACCJ DNA mismatch repair protein MutS O...6112e-38     158     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
182A1B095    878   MUTS_PARDP DNA mismatch repair protein MutS O...5732e-38     158     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
183Q3MHE4    934   MSH2_BOVIN DNA mismatch repair protein Msh2 O...6812e-38     158     26     44GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
184Q7MXR7    891   MUTS_PORGI DNA mismatch repair protein MutS O...6213e-38     157     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
185P43246    934   MSH2_HUMAN DNA mismatch repair protein Msh2 O...6953e-38     157     26     44GO:0032301; C:MutSalpha complex; IDA:HGNC.::GO:0032302; C:MutSbeta complex; IDA:HGNC.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IMP:MGI.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:HGNC.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0030183; P:B cell differentiation; ISS:BHF-UCL.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; ISS:BHF-UCL.::GO:0043570; P:maintenance of DNA repeat elements; IMP:HGNC.::GO:0008584; P:male gonad development; ISS:BHF-UCL.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.::GO:0006301; P:postreplication repair; IDA:UniProtKB.::GO:0010224; P:response to UV-B; ISS:BHF-UCL.::GO:0010165; P:response to X-ray; ISS:BHF-UCL.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
186A1U2E8    874   MUTS_MARAV DNA mismatch repair protein MutS O...5693e-38     157     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
187B4UCY7    882   MUTS_ANASK DNA mismatch repair protein MutS O...2744e-38     157     32     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
188Q56215    811   MUTS_THEAQ DNA mismatch repair protein MutS O...6164e-38     157     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
189Q317Z7    913   MUTS_PROM9 DNA mismatch repair protein MutS O...3074e-38     157     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
190Q5XXB5    933   MSH2_CHLAE DNA mismatch repair protein Msh2 O...6914e-38     157     26     44GO:0032301; C:MutSalpha complex; IEA:InterPro.::GO:0032302; C:MutSbeta complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006298; P:mismatch repair; IEA:InterPro.
191O74773    982   MSH2_SCHPO DNA mismatch repair protein msh2 O...6916e-38     157     24     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0032301; C:MutSalpha complex; ISS:RefGenome.::GO:0032302; C:MutSbeta complex; ISS:RefGenome.::GO:0000228; C:nuclear chromosome; ISS:PomBase.
GO:0005524; F:ATP binding; ISS:PomBase.::GO:0003684; F:damaged DNA binding; ISS:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; ISS:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; ISS:PomBase.::GO:0000400; F:four-way junction DNA binding; ISS:PomBase.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0000403; F:Y-form DNA binding; ISS:PomBase.
GO:0043570; P:maintenance of DNA repeat elements; IMP:PomBase.::GO:0006311; P:meiotic gene conversion; ISS:RefGenome.::GO:0000710; P:meiotic mismatch repair; ISS:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; ISS:RefGenome.::GO:0006301; P:postreplication repair; ISS:RefGenome.::GO:0000735; P:removal of nonhomologous ends; ISS:RefGenome.
192Q1H2P1    884   MUTS_METFK DNA mismatch repair protein MutS O...5789e-38     156     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
193C0ZEZ4    862   MUTS_BREBN DNA mismatch repair protein MutS O...5859e-38     156     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
194Q49X88    887   MUTS_STAS1 DNA mismatch repair protein MutS O...3201e-37     155     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
195Q46IE5    926   MUTS_PROMT DNA mismatch repair protein MutS O...3231e-37     155     32     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
196A6U5G0    915   MUTS_SINMW DNA mismatch repair protein MutS O...5821e-37     155     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
197B5E385    844   MUTS_STRP4 DNA mismatch repair protein MutS O...6382e-37     155     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
198Q6MBV4    858   MUTS_PARUW DNA mismatch repair protein MutS O...3082e-37     155     32     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
199Q2JT35    882   MUTS_SYNJA DNA mismatch repair protein MutS O...6202e-37     155     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
200P43247    935   MSH2_MOUSE DNA mismatch repair protein Msh2 O...6822e-37     155     26     43GO:0032301; C:MutSalpha complex; IDA:MGI.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019237; F:centromeric DNA binding; IDA:MGI.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0007050; P:cell cycle arrest; IMP:MGI.::GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IMP:MGI.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0031573; P:intra-S DNA damage checkpoint; IGI:MGI.::GO:0045190; P:isotype switching; IMP:MGI.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006119; P:oxidative phosphorylation; IMP:MGI.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0010224; P:response to UV-B; IMP:MGI.::GO:0010165; P:response to X-ray; IMP:MGI.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.
201P54275    933   MSH2_RAT DNA mismatch repair protein Msh2 OS=...6872e-37     155     26     43GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IEP:RGD.
202Q38YR4    867   MUTS_LACSS DNA mismatch repair protein MutS O...5993e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
203Q3A4F1    870   MUTS_PELCD DNA mismatch repair protein MutS O...6763e-37     154     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
204Q8XL87    909   MUTS_CLOPE DNA mismatch repair protein MutS O...5823e-37     154     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
205A0LG76    889   MUTS_SYNFM DNA mismatch repair protein MutS O...6683e-37     154     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
206P65494    872   MUTS_STAAW DNA mismatch repair protein MutS O...5903e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
207P0C1S1    872   MUTS_STAAU DNA mismatch repair protein MutS O...5903e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
208A8Z1W6    872   MUTS_STAAT DNA mismatch repair protein MutS O...5903e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
209Q6G9R8    872   MUTS_STAAS DNA mismatch repair protein MutS O...5903e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
210P65493    872   MUTS_STAAN DNA mismatch repair protein MutS O...5903e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
211Q931S8    872   MUTS_STAAM DNA mismatch repair protein MutS O...5903e-37     154     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
GO:0006298; P:mismatch repair; IEA:InterPro.
records
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