Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL132W
Length:
815
Number of sequences:
5887
Description:
YDL132W CDC53 SGDID:S000002290, Chr IV from 224304-226751, Genome Release 64-1-1, Verified ORF, "Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9JJ31    780   CUL5_RAT Cullin-5 OS=Rattus norvegicus (Rat)....8406e-45     177     24     44GO:0031466; C:Cul5-RING ubiquitin ligase complex; TAS:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:RGD.::GO:0005000; F:vasopressin receptor activity; TAS:RGD.
GO:0051480; P:cytosolic calcium ion homeostasis; IMP:RGD.::GO:0000209; P:protein polyubiquitination; TAS:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
32Q9D5V5    780   CUL5_MOUSE Cullin-5 OS=Mus musculus (Mouse). ...8402e-44     175     24     44GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
33Q93034    780   CUL5_HUMAN Cullin-5 OS=Homo sapiens (Human). ...8504e-44     174     24     43GO:0031466; C:Cul5-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005262; F:calcium channel activity; TAS:ProtInc.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016032; P:viral reproduction; TAS:Reactome.
34Q5RB36    780   CUL5_PONAB Cullin-5 OS=Pongo abelii (Sumatran...8508e-44     173     24     43GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
35Q13619    759   CUL4A_HUMAN Cullin-4A OS=Homo sapiens (Human)...8322e-43     172     23     43GO:0031464; C:Cul4A-RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
36Q3TCH7    759   CUL4A_MOUSE Cullin-4A OS=Mus musculus (Mouse)...6164e-43     171     26     43GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0045750; P:positive regulation of S phase of mitotic cell cycle; IMP:MGI.::GO:0051246; P:regulation of protein metabolic process; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
37Q29425    780   CUL5_RABIT Cullin-5 OS=Oryctolagus cuniculus ...8505e-43     171     24     43GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
38A2A432    970   CUL4B_MOUSE Cullin-4B OS=Mus musculus (Mouse)...6092e-41     167     26     45GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IMP:MGI.::GO:0045750; P:positive regulation of S phase of mitotic cell cycle; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
39Q13620    913   CUL4B_HUMAN Cullin-4B OS=Homo sapiens (Human)...6092e-41     167     26     46GO:0031465; C:Cul4B-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
40Q54CS2    802   CUL4_DICDI Cullin-4 OS=Dictyostelium discoide...6882e-38     157     25     44GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005634; C:nucleus; IDA:dictyBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
41Q09760    785   CUL3_SCHPO Cullin-3 OS=Schizosaccharomyces po...8523e-38     156     23     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:PomBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
42Q17392    840   CUL4_CAEEL Cullin-4 OS=Caenorhabditis elegans...7574e-33     140     22     43GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
43O14122    734   CUL4_SCHPO Cullin-4 OS=Schizosaccharomyces po...6184e-32     137     24     43GO:0043494; C:CLRC ubiquitin ligase complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031618; C:nuclear centromeric heterochromatin; TAS:PomBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0031048; P:chromatin silencing by small RNA; IMP:PomBase.::GO:0007535; P:donor selection; TAS:PomBase.::GO:0031507; P:heterochromatin assembly; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0045836; P:positive regulation of meiosis; IGI:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:PomBase.::GO:0051570; P:regulation of histone H3-K9 methylation; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:PomBase.
44P53202    744   CUL3_YEAST Cullin-3 OS=Saccharomyces cerevisi...6204e-19     95.9     24     42GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.
45Q9XIE9    374   CLL2_ARATH Putative cullin-like protein 2 OS=...3510.000000000003     72.8     23     44GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
46Q9UJX6    822   ANC2_HUMAN Anaphase-promoting complex subunit...2300.0000004     57.8     24     45GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.
47P47050    842   CUL8_YEAST Regulator of Ty1 transposition pro...3520.0000006     57     22     41GO:0035361; C:Cul8-RING ubiquitin ligase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
GO:0010526; P:negative regulation of transposition, RNA-mediated; IMP:SGD.::GO:0070651; P:nonfunctional rRNA decay; IMP:SGD.::GO:0007088; P:regulation of mitosis; IMP:SGD.::GO:0031297; P:replication fork processing; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:SGD.
48Q8BZQ7    837   ANC2_MOUSE Anaphase-promoting complex subunit...2300.00004     50.8     22     45GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
49Q9XIE8    255   CLL3_ARATH Cullin-like protein 3 OS=Arabidops...2700.0001     48.5     18     41GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
50Q9SZ75    434   CLL5_ARATH Cullin-like protein 5 OS=Arabidops...1510.68     37     23     46GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
records
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