UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL131W

Length:

440

Number of sequences:

5887

Description:

YDL131W LYS21 SGDID:S000002289, Chr IV from 227393-228715, Genome Release 64-1-1, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
331	A8H9A1	523	LEU1_SHEPA 2-isopropylmalate synthase OS=Shew...	346	6e-32	130	28	48
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
332	Q01181	391	NIFV_RHOSH Homocitrate synthase OS=Rhodobacte...	321	6e-32	129	31	45
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
333	Q12SE7	522	LEU1_SHEDO 2-isopropylmalate synthase OS=Shew...	378	7e-32	130	28	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
334	Q31I16	514	LEU11_THICR 2-isopropylmalate synthase 1 OS=T...	377	8e-32	130	27	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
335	A1SRG8	519	LEU1_PSYIN 2-isopropylmalate synthase OS=Psyc...	361	8e-32	130	27	50
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
336	A5GRZ0	537	LEU1_SYNR3 2-isopropylmalate synthase OS=Syne...	399	1e-31	130	27	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
337	B0TQM0	523	LEU1_SHEHH 2-isopropylmalate synthase OS=Shew...	346	1e-31	130	28	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
338	Q8XXP1	513	LEU11_RALSO 2-isopropylmalate synthase 1 OS=R...	388	1e-31	129	29	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
339	B2VDA7	522	LEU1_ERWT9 2-isopropylmalate synthase OS=Erwi...	359	1e-31	129	27	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
340	B8CM39	523	LEU1_SHEPW 2-isopropylmalate synthase OS=Shew...	340	1e-31	129	28	48
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
341	Q7MP77	515	LEU1_VIBVY 2-isopropylmalate synthase OS=Vibr...	361	1e-31	129	28	46
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
342	Q8DEE1	515	LEU1_VIBVU 2-isopropylmalate synthase OS=Vibr...	361	1e-31	129	28	46
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
343	A1W6T7	512	LEU1_ACISJ 2-isopropylmalate synthase OS=Acid...	382	1e-31	129	29	46
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
344	B9MA32	512	LEU1_ACIET 2-isopropylmalate synthase OS=Acid...	382	1e-31	129	29	46
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
345	A4SXR0	515	LEU1_POLSQ 2-isopropylmalate synthase OS=CIP ...	390	2e-31	129	28	44
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
346	B7VIF2	515	LEU1_VIBSL 2-isopropylmalate synthase OS=Vibr...	362	2e-31	129	28	48
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
347	B1XUJ3	515	LEU1_POLNS 2-isopropylmalate synthase OS=Poly...	381	2e-31	129	28	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
348	Q0KCT8	513	LEU1_CUPNH 2-isopropylmalate synthase OS=(Ral...	366	6e-31	127	29	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
349	Q473V1	513	LEU1_CUPPJ 2-isopropylmalate synthase OS=eutr...	382	8e-31	127	28	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
350	A1WNY5	512	LEU1_VEREI 2-isopropylmalate synthase OS=Verm...	382	9e-31	127	27	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
351	Q9WZ22	538	LY41_THEMA Uncharacterized AIPM/Hcit synthase...	365	9e-31	127	27	48
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
352	Q07179	382	NIFV_RHOCA Homocitrate synthase OS=Rhodobacte...	317	1e-30	125	31	45
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
353	Q00853	269	NIFVA_CLOPA Homocitrate synthase subunit alph...	223	1e-30	123	34	53
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
354	C7M0E4	516	LEU1_ACIFD 2-isopropylmalate synthase OS=1038...	399	1e-30	127	27	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
355	P54610	401	NIFV_FRASP Homocitrate synthase OS=Frankia sp...	353	1e-30	125	26	44
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
356	A5CWZ3	511	LEU1_VESOH 2-isopropylmalate synthase OS=Vesi...	390	2e-30	125	28	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
357	A0KGM9	524	LEU1_AERHH 2-isopropylmalate synthase OS=Aero...	360	3e-30	125	27	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
358	A2SHL8	513	LEU1_METPP 2-isopropylmalate synthase OS=Meth...	378	5e-30	125	29	44
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
359	C5B7R4	526	LEU1_EDWI9 2-isopropylmalate synthase OS=Edwa...	340	1e-29	124	29	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
360	Q0BDB9	514	LEU1_BURCM 2-isopropylmalate synthase OS=cepa...	374	2e-29	123	29	44
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
361	Q12B47	513	LEU1_POLSJ 2-isopropylmalate synthase OS=Pola...	382	3e-29	122	28	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.

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