Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL128W
Length:
411
Number of sequences:
5887
Description:
YDL128W VCX1 SGDID:S000002286, Chr IV from 232652-233887, Genome Release 64-1-1, Verified ORF, "Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity, involved in control of cytosolic Ca2+ and K+ concentrations; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q99385    411   VCX1_YEAST Vacuolar calcium ion transporter O...4110     828     100     100GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015369; F:calcium:hydrogen antiporter activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015386; F:potassium:hydrogen antiporter activity; IMP:SGD.
GO:0006874; P:cellular calcium ion homeostasis; IMP:SGD.
2O59768    412   VCX1_SCHPO Vacuolar calcium ion transporter O...3691e-120     363     51     73GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000324; C:fungal-type vacuole; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015085; F:calcium ion transmembrane transporter activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006874; P:cellular calcium ion homeostasis; IMP:PomBase.
3Q6K1C4    417   CAX3_ORYSJ Vacuolar cation/proton exchanger 3...3837e-86     274     40     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
4Q8L783    441   CAX5_ARATH Vacuolar cation/proton exchanger 5...3761e-84     271     41     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
5Q5KQN0    437   CAX2_ORYSJ Vacuolar cation/proton exchanger 2...3889e-84     269     40     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
6Q39254    441   CAX2_ARATH Vacuolar cation/proton exchanger 2...3941e-83     269     40     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0015369; F:calcium:hydrogen antiporter activity; IDA:TAIR.
GO:0015691; P:cadmium ion transport; IGI:TAIR.::GO:0006828; P:manganese ion transport; IGI:TAIR.
7Q9LFZ8    448   CAX6_ARATH Putative vacuolar cation/proton ex...3922e-77     253     39     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
8Q93Z81    459   CAX3_ARATH Vacuolar cation/proton exchanger 3...3806e-73     241     38     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0015369; F:calcium:hydrogen antiporter activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006874; P:cellular calcium ion homeostasis; IGI:TAIR.::GO:0030026; P:cellular manganese ion homeostasis; IGI:TAIR.::GO:0006882; P:cellular zinc ion homeostasis; IGI:TAIR.::GO:0010351; P:lithium ion transport; IGI:TAIR.::GO:0055062; P:phosphate ion homeostasis; IGI:TAIR.::GO:0006793; P:phosphorus metabolic process; IGI:TAIR.::GO:0051592; P:response to calcium ion; IMP:TAIR.::GO:0009624; P:response to nematode; IEP:TAIR.::GO:0006814; P:sodium ion transport; IGI:TAIR.
9Q5TKG3    453   CAX1B_ORYSJ Vacuolar cation/proton exchanger ...3389e-72     238     39     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
10Q39253    463   CAX1_ARATH Vacuolar cation/proton exchanger 1...3703e-70     234     38     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0015369; F:calcium:hydrogen antiporter activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030026; P:cellular manganese ion homeostasis; IMP:TAIR.::GO:0006882; P:cellular zinc ion homeostasis; IMP:TAIR.::GO:0009631; P:cold acclimation; IMP:TAIR.::GO:0055062; P:phosphate ion homeostasis; IGI:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.
11Q945S5    446   CAX4_ARATH Vacuolar cation/proton exchanger 4...3895e-70     233     36     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0015369; F:calcium:hydrogen antiporter activity; IMP:TAIR.
GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.
12Q769E5    451   CAX1A_ORYSJ Vacuolar cation/proton exchanger ...3784e-69     231     40     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
13Q6YXZ1    447   CAX4_ORYSJ Putative vacuolar cation/proton ex...3773e-66     223     38     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
14O34840    351   YFKE_BACSU Putative cation exchanger yfkE OS=...3512e-65     219     39     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
15Q5KTQ9    450   CAX1C_ORYSJ Vacuolar cation/proton exchanger ...3784e-53     189     34     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
16P42839    908   VNX1_YEAST Low affinity vacuolar monovalent c...3715e-27     117     25     46GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015369; F:calcium:hydrogen antiporter activity; IMP:SGD.::GO:0015386; F:potassium:hydrogen antiporter activity; IMP:SGD.::GO:0015385; F:sodium:hydrogen antiporter activity; IMP:SGD.
17Q9P7B3    881   YI14_SCHPO Putative cation exchanger C521.04c...1920.000000002     63.2     26     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; IEA:InterPro.
18P55471    367   Y4HA_RHISN Putative ionic transporter y4hA OS...3110.00000004     58.5     21     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
19Q9U6A0    881   NCKX_DROME Sodium/potassium/calcium exchanger...1310.27     37.4     24     43GO:0016021; C:integral to membrane; IDA:UniProtKB.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:UniProtKB.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0048749; P:compound eye development; IEP:FlyBase.
20Q9IAL7    651   NCKX2_CHICK Sodium/potassium/calcium exchange...860.27     37.4     29     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
21Q9IAL8    663   NCKX1_CHICK Sodium/potassium/calcium exchange...860.68     35.8     28     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:InterPro.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
22Q9HC58    644   NCKX3_HUMAN Sodium/potassium/calcium exchange...1321.4     35     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
23Q99PD7    645   NCKX3_MOUSE Sodium/potassium/calcium exchange...1861.7     34.7     21     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:MGI.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:MGI.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0006874; P:cellular calcium ion homeostasis; TAS:MGI.
24Q9EPQ0    624   NCKX3_RAT Sodium/potassium/calcium exchanger ...1321.8     34.7     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:RGD.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0006874; P:cellular calcium ion homeostasis; IEP:RGD.
25Q28139    1216   NCKX1_BOVIN Sodium/potassium/calcium exchange...744.9     33.1     27     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:InterPro.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
26P31801    366   CHAA_ECOLI Calcium/proton antiporter OS=Esche...3645.2     32.7     21     40GO:0005887; C:integral to plasma membrane; IDA:EcoliWiki.
GO:0015386; F:potassium:hydrogen antiporter activity; IDA:EcoCyc.::GO:0015385; F:sodium:hydrogen antiporter activity; IDA:EcoCyc.
GO:0030007; P:cellular potassium ion homeostasis; IGI:EcoCyc.::GO:0006883; P:cellular sodium ion homeostasis; IGI:EcoCyc.
27O60721    1099   NCKX1_HUMAN Sodium/potassium/calcium exchange...705.2     33.1     29     59GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0019867; C:outer membrane; NAS:UniProtKB.
GO:0008273; F:calcium, potassium:sodium antiporter activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0009642; P:response to light intensity; NAS:UniProtKB.::GO:0007601; P:visual perception; NAS:UniProtKB.
28Q8C261    501   NCKX5_MOUSE Sodium/potassium/calcium exchange...485.3     33.1     38     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
29Q9QZM6    1181   NCKX1_RAT Sodium/potassium/calcium exchanger ...745.5     33.1     27     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:InterPro.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
30Q49SH1    513   NCKX5_DANRE Sodium/potassium/calcium exchange...1327.5     32.3     28     50GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.::GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
31P45394    325   YRBG_ECOLI Inner membrane protein yrbG OS=Esc...609.3     32     30     55GO:0005887; C:integral to plasma membrane; IDA:EcoliWiki.
GO:0005432; F:calcium:sodium antiporter activity; NAS:EcoCyc.
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