Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL126C
Length:
835
Number of sequences:
5887
Description:
YDL126C CDC48 SGDID:S000002284, Chr IV from 238664-236157, Genome Release 64-1-1, reverse complement, Verified ORF, "ATPase involved in ubiquitin-mediated protein degradation; Cdc48p-Npl4p-Ufd1p complex participates in ER-associated degradation (ERAD) while Cdc48p-Npl4p-Vms1p complex participates in mitochondria-associated degradation (MAD); along with Npl4-Ufd1 complex, important for maintaining the cell wall integrity during heat stress to allow G1 progression"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q9HNP9    411   PAN2_HALSA Proteasome-activating nucleotidase...2422e-54     198     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
122B9KXV3    652   FTSH1_THERP ATP-dependent zinc metalloproteas...2384e-56     209     45     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
123D1CDT8    646   FTSH_THET1 ATP-dependent zinc metalloprotease...2431e-54     204     44     67GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
124O42931    438   PRS7_SCHPO 26S protease regulatory subunit 7 ...2591e-49     185     38     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004175; F:endopeptidase activity; ISS:PomBase.
GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
125Q8X9L0    644   FTSH_ECO57 ATP-dependent zinc metalloprotease...2373e-53     200     44     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
126P0AAI4    644   FTSH_SHIFL ATP-dependent zinc metalloprotease...2373e-53     200     44     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
127P0AAI3    644   FTSH_ECOLI ATP-dependent zinc metalloprotease...2373e-53     200     44     65GO:0016021; C:integral to membrane; IDA:EcoliWiki.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:EcoliWiki.::GO:0043273; F:CTPase activity; IDA:EcoliWiki.::GO:0030145; F:manganese ion binding; IDA:EcoliWiki.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:EcoliWiki.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:EcoliWiki.
128Q01939    405   PRS8_YEAST 26S protease regulatory subunit 8 ...2508e-55     199     41     58GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0019904; F:protein domain specific binding; IDA:SGD.
GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0006289; P:nucleotide-excision repair; IGI:SGD.::GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IPI:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.
129P40327    437   PRS4_YEAST 26S protease regulatory subunit 4 ...2552e-44     171     37     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043171; P:peptide catabolic process; IMP:SGD.::GO:0045732; P:positive regulation of protein catabolic process; IDA:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
130Q9SL67    443   PRS4B_ARATH 26S proteasome regulatory subunit...2293e-46     176     40     60GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007292; P:female gamete generation; IGI:TAIR.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0048232; P:male gamete generation; IGI:TAIR.::GO:0030163; P:protein catabolic process; IEA:InterPro.
131Q5R8D7    433   PRS7_PONAB 26S protease regulatory subunit 7 ...2952e-52     193     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
132O18413    405   PRS8_DROME 26S protease regulatory subunit 8 ...2288e-58     207     44     68GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0004175; F:endopeptidase activity; IDA:FlyBase.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
133P54814    402   PRS8_MANSE 26S protease regulatory subunit 8 ...2288e-58     207     44     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
134Q9SSB4    464   PRS7B_ARATH 26S protease regulatory subunit 7...2594e-52     193     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
135P54778    413   PRS6B_SOLTU 26S protease regulatory subunit 6...2315e-52     191     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
136Q55BV5    439   PRS4_DICDI 26S protease regulatory subunit 4 ...2274e-47     178     39     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
137P46471    433   PRS7_MOUSE 26S protease regulatory subunit 7 ...2955e-52     192     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
138Q89AF2    610   FTSH_BUCBP ATP-dependent zinc metalloprotease...2401e-50     191     40     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
139Q4R4R0    433   PRS7_MACFA 26S protease regulatory subunit 7 ...2955e-52     192     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
140P35998    433   PRS7_HUMAN 26S protease regulatory subunit 7 ...2955e-52     192     36     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
141Q5E9F9    433   PRS7_BOVIN 26S protease regulatory subunit 7 ...2955e-52     192     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
142P46472    433   PRS7_XENLA 26S protease regulatory subunit 7 ...2956e-52     192     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
143Q63347    433   PRS7_RAT 26S protease regulatory subunit 7 OS...2956e-52     191     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
144P46466    448   PRS4_ORYSJ 26S protease regulatory subunit 4 ...2272e-46     176     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
145Q18787    435   PRS7_CAEEL 26S protease regulatory subunit 7 ...2951e-51     191     35     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
146Q8K9G8    613   FTSH_BUCAP ATP-dependent zinc metalloprotease...2213e-51     194     44     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
147P54816    1291   TBP7_CAEEL Tat-binding homolog 7 OS=Caenorhab...2722e-48     190     42     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0031445; P:regulation of heterochromatin assembly; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
148P46507    415   PRS6B_MANSE 26S protease regulatory subunit 6...2332e-50     187     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
149P53549    437   PRS10_YEAST 26S protease subunit RPT4 OS=Sacc...2555e-53     195     40     56GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0019904; F:protein domain specific binding; IDA:SGD.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006289; P:nucleotide-excision repair; IGI:SGD.::GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.
150Q9SZD4    443   PRS4A_ARATH 26S proteasome regulatory subunit...2273e-46     176     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007292; P:female gamete generation; IGI:TAIR.::GO:0010386; P:lateral root primordium development; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0048232; P:male gamete generation; IGI:TAIR.::GO:0035266; P:meristem growth; IMP:TAIR.::GO:0009933; P:meristem structural organization; IMP:TAIR.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:TAIR.::GO:0043248; P:proteasome assembly; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0051788; P:response to misfolded protein; IMP:TAIR.::GO:0048829; P:root cap development; IMP:TAIR.::GO:0090351; P:seedling development; IMP:TAIR.
151P63343    644   FTSH_SALTY ATP-dependent zinc metalloprotease...2372e-53     200     44     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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