Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL124W
Length:
312
Number of sequences:
5887
Description:
YDL124W YDL124W SGDID:S000002282, Chr IV from 240259-241197, Genome Release 64-1-1, Verified ORF, "NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61A3PXS9    283   Y1918_MYCSJ Uncharacterized oxidoreductase Mj...2811e-29     119     30     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
62Q6AZW2    324   A1A1A_DANRE Alcohol dehydrogenase [NADP(+)] A...2981e-29     120     30     46
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
63Q95JH7    323   AK1C1_MACFA Aldo-keto reductase family 1 memb...3301e-29     119     31     47GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
64P42330    323   AK1C3_HUMAN Aldo-keto reductase family 1 memb...3102e-29     119     32     47GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB.
65Q95JH5    323   AK1C4_MACFA Aldo-keto reductase family 1 memb...3112e-29     119     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC.
66A1UEC5    283   Y1984_MYCSK Uncharacterized oxidoreductase Mk...2812e-29     118     30     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
67Q1BAN7    283   Y1938_MYCSS Uncharacterized oxidoreductase Mm...2812e-29     118     30     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
68Q7G764    321   NADO1_ORYSJ Probable NAD(P)H-dependent oxidor...2762e-29     119     31     52
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
69Q9M338    315   AKRCB_ARATH Aldo-keto reductase family 4 memb...3035e-29     117     30     47GO:0005829; C:cytosol; IDA:TAIR.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.
70Q95JH4    323   AK1C4_MACFU Aldo-keto reductase family 1 memb...3115e-29     117     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC.
71Q5BGA7    319   XYL1_EMENI Probable NAD(P)H-dependent D-xylos...3076e-29     117     29     47
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
72P05980    323   PGFS1_BOVIN Prostaglandin F synthase 1 OS=Bos...3106e-29     117     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.
GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW.
73P26690    315   6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone...2867e-29     117     32     51
GO:0033808; F:6'-deoxychalcone synthase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW.
74P17516    323   AK1C4_HUMAN Aldo-keto reductase family 1 memb...3047e-29     117     34     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.
75P06632    278   DKGA_CORSC 2,5-diketo-D-gluconic acid reducta...2808e-29     116     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
76Q7G765    322   NADO2_ORYSJ Probable NAD(P)H-dependent oxidor...2961e-28     116     28     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
77P52895    323   AK1C2_HUMAN Aldo-keto reductase family 1 memb...3101e-28     116     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB.
78C5FFQ7    327   XYL1_ARTOC Probable NAD(P)H-dependent D-xylos...3081e-28     116     30     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
79Q6GMC7    327   AK1A1_XENLA Alcohol dehydrogenase [NADP(+)] O...3092e-28     116     32     49
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
80P52897    323   PGFS2_BOVIN Prostaglandin F synthase 2 OS=Bos...3102e-28     116     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.
GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW.
81Q8VC28    323   AK1CD_MOUSE Aldo-keto reductase family 1 memb...3102e-28     116     29     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006805; P:xenobiotic metabolic process; TAS:MGI.
82A0PQ11    282   Y1987_MYCUA Uncharacterized oxidoreductase MU...2825e-28     114     29     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
83Q4WJT9    315   XYL1_ASPFU Probable NAD(P)H-dependent D-xylos...3076e-28     114     29     47
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
84B0XNR0    315   XYL1_ASPFC Probable NAD(P)H-dependent D-xylos...3076e-28     114     29     47
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
85Q02198    296   MORA_PSEPU Morphine 6-dehydrogenase OS=Pseudo...2926e-28     114     29     49
GO:0050109; F:morphine 6-dehydrogenase activity; IEA:EC.
GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW.
86P23457    322   DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase...3058e-28     114     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.
GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD.
87Q9C1X5    283   YKW2_SCHPO Uncharacterized oxidoreductase P32...2869e-28     114     33     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0032866; F:D-xylose:NADP reductase activity; ISS:PomBase.::GO:0032867; F:L-arabinose:NADP reductase activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
88Q04828    323   AK1C1_HUMAN Aldo-keto reductase family 1 memb...3301e-27     114     30     46GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.::GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB.
89B2HIJ9    281   Y1744_MYCMM Uncharacterized oxidoreductase MM...2822e-27     112     28     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
90Q6W8P9    323   AK1CO_HORSE Aldo-keto reductase family 1 memb...3103e-27     113     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
91Q8K023    323   AKC1H_MOUSE Aldo-keto reductase family 1 memb...2993e-27     113     31     49
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI.
GO:0007567; P:parturition; IMP:MGI.::GO:0006709; P:progesterone catabolic process; IDA:MGI.
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