Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL124W
Length:
312
Number of sequences:
5887
Description:
YDL124W YDL124W SGDID:S000002282, Chr IV from 240259-241197, Genome Release 64-1-1, Verified ORF, "NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q8ZI40    277   DKGA_YERPE 2,5-diketo-D-gluconic acid reducta...2841e-32     127     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
32P70694    323   DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 ...3102e-32     127     32     51
GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:MGI.
GO:0006694; P:steroid biosynthetic process; IDA:MGI.
33O32210    276   GR_BACSU Glyoxal reductase OS=Bacillus subtil...2492e-32     126     35     56
GO:0043892; F:methylglyoxal reductase (NADPH-dependent) activity; IEA:EC.
34Q10494    321   YDG7_SCHPO Uncharacterized oxidoreductase C26...3067e-32     125     35     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
35A0QJ99    284   Y3816_MYCA1 Uncharacterized oxidoreductase MA...2828e-32     125     30     50
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
36P51635    325   AK1A1_RAT Alcohol dehydrogenase [NADP(+)] OS=...3008e-32     125     32     47
37Q5ZK84    327   AK1A1_CHICK Alcohol dehydrogenase [NADP(+)] O...3138e-32     125     34     47
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
38O13283    324   XYL1_CANTR NAD(P)H-dependent D-xylose reducta...3109e-32     125     30     50
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
39Q9TV64    326   AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen...3011e-31     125     33     47
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
40Q84TF0    314   AKRCA_ARATH Aldo-keto reductase family 4 memb...3032e-31     124     32     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
41P38115    344   ARA1_YEAST D-arabinose dehydrogenase [NAD(P)+...3202e-31     125     33     49GO:0005829; C:cytosol; IDA:SGD.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:SGD.::GO:0045290; F:D-arabinose 1-dehydrogenase [NAD(P)+ activity; IDA:SGD.
GO:0044262; P:cellular carbohydrate metabolic process; IMP:SGD.]
42Q0PGJ6    315   AKRC9_ARATH Aldo-keto reductase family 4 memb...3033e-31     124     35     48GO:0009507; C:chloroplast; IDA:TAIR.
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:TAIR.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB.
GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.
43O69462    282   Y1669_MYCLE Uncharacterized oxidoreductase ML...2933e-31     123     30     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
44B8ZS00    282   Y1669_MYCLB Uncharacterized oxidoreductase ML...2933e-31     123     30     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
45P51857    326   AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen...3013e-31     124     33     48GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB.
GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.
46O42888    325   YBN4_SCHPO Uncharacterized oxidoreductase C8E...3073e-31     124     32     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
47Q8VCX1    325   AK1D1_MOUSE 3-oxo-5-beta-steroid 4-dehydrogen...3076e-31     123     32     49
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
48Q73VK6    281   Y3007_MYCPA Uncharacterized oxidoreductase MA...2828e-31     122     29     50
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
49Q9P430    323   XYL1_CANSH NAD(P)H-dependent D-xylose reducta...3121e-30     122     31     50
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
50P31867    318   XYL1_PICST NAD(P)H-dependent D-xylose reducta...3111e-30     122     32     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
51Q9JII6    325   AK1A1_MOUSE Alcohol dehydrogenase [NADP(+)] O...3001e-30     122     32     46GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.::GO:0047939; F:L-glucuronate reductase activity; IDA:MGI.
GO:0046185; P:aldehyde catabolic process; IDA:MGI.::GO:0042840; P:D-glucuronate catabolic process; IDA:MGI.::GO:0019853; P:L-ascorbic acid biosynthetic process; IDA:MGI.
52Q95JH6    323   AK1C1_MACFU Aldo-keto reductase family 1 memb...3302e-30     122     31     47GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
53Q3ZCJ2    325   AK1A1_BOVIN Alcohol dehydrogenase [NADP(+)] O...3012e-30     122     31     47
54P78736    318   XYL1_PACTA NAD(P)H-dependent D-xylose reducta...3133e-30     121     31     46
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
55Q0CUL0    320   XYL1_ASPTN Probable NAD(P)H-dependent D-xylos...3115e-30     120     31     47
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
56O34678    280   YTBE_BACSU Uncharacterized oxidoreductase Ytb...3025e-30     120     33     54
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
57O74237    322   XYL1_CANTE NAD(P)H-dependent D-xylose reducta...2767e-30     120     32     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
58Q5R7C9    323   AK1C3_PONAB Aldo-keto reductase family 1 memb...3117e-30     120     32     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC.
GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB.
59Q9P8R5    319   XYL1_ASPNG NAD(P)H-dependent D-xylose reducta...3079e-30     120     29     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
60A2Q8B5    319   XYL1_ASPNC Probable NAD(P)H-dependent D-xylos...3079e-30     120     29     48
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
61A3PXS9    283   Y1918_MYCSJ Uncharacterized oxidoreductase Mj...2811e-29     119     30     49
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
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