Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL124W
Length:
312
Number of sequences:
5887
Description:
YDL124W YDL124W SGDID:S000002282, Chr IV from 240259-241197, Genome Release 64-1-1, Verified ORF, "NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q4R802    320   AKCL2_MACFA 1,5-anhydro-D-fructose reductase ...2733e-23     101     29     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC.
122P15339    277   DKGB_CORSS 2,5-diketo-D-gluconic acid reducta...2824e-23     100     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
123P07943    316   ALDR_RAT Aldose reductase OS=Rattus norvegicu...2941e-22     99.8     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:RGD.
GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.::GO:0006061; P:sorbitol biosynthetic process; IMP:RGD.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD.
124P45376    316   ALDR_MOUSE Aldose reductase OS=Mus musculus (...2941e-22     99.4     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.
125Q6AYQ2    318   AK1CL_RAT Aldo-keto reductase family 1 member...2922e-22     98.6     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
126P30863    267   DKGB_ECOLI 2,5-diketo-D-gluconic acid reducta...2713e-22     97.8     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.::GO:0004033; F:aldo-keto reductase (NADP) activity; EXP:EcoCyc.::GO:0047681; F:aryl-alcohol dehydrogenase (NADP+) activity; IDA:EcoCyc.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
127Q8ZRM7    267   DKGB_SALTY 2,5-diketo-D-gluconic acid reducta...2432e-21     95.1     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
128Q8Z988    267   DKGB_SALTI 2,5-diketo-D-gluconic acid reducta...2433e-21     94.7     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
129Q8X7Z7    267   DKGB_ECO57 2,5-diketo-D-gluconic acid reducta...2715e-21     94.4     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
130Q9USV2    276   YHH5_SCHPO Uncharacterized oxidoreductase C28...2457e-21     93.6     29     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0032866; F:D-xylose:NADP reductase activity; ISS:PomBase.::GO:0032867; F:L-arabinose:NADP reductase activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
131P45377    316   ALD2_MOUSE Aldose reductase-related protein 2...3001e-20     93.6     31     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
132P80276    316   ALDR_PIG Aldose reductase OS=Sus scrofa (Pig)...3081e-20     93.2     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
133P15121    316   ALDR_HUMAN Aldose reductase OS=Homo sapiens (...2941e-20     93.2     30     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.::GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.::GO:0006950; P:response to stress; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
134P16116    315   ALDR_BOVIN Aldose reductase OS=Bos taurus (Bo...2991e-20     93.2     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
135P15122    316   ALDR_RABIT Aldose reductase OS=Oryctolagus cu...2962e-20     93.2     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
136A0QL30    286   Y4483_MYCA1 Uncharacterized oxidoreductase MA...2944e-20     91.7     28     52
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
137Q5U1Y4    301   AKCL2_RAT 1,5-anhydro-D-fructose reductase OS...1561e-19     90.1     33     55
GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC.
138Q01213    321   DTDH_MUCMU 4-dihydromethyl-trisporate dehydro...3041e-19     90.5     27     42
GO:0016696; F:oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor; NAS:UniProtKB.
GO:0046842; P:trisporic acid biosynthetic process; NAS:UniProtKB.
139Q73SC5    286   Y4149_MYCPA Uncharacterized oxidoreductase MA...2942e-19     89.7     28     51
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
140O70473    228   AK1A1_CRIGR Alcohol dehydrogenase [NADP(+)] O...2382e-19     88.6     31     43
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
141O08782    316   ALD2_CRIGR Aldose reductase-related protein 2...3033e-19     89.4     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
142Q9DCT1    301   AKCL2_MOUSE 1,5-anhydro-D-fructose reductase ...2913e-19     89.4     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC.
143P21300    316   ALD1_MOUSE Aldose reductase-related protein 1...3006e-19     88.6     29     46GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
GO:0044255; P:cellular lipid metabolic process; TAS:MGI.
144Q8ZH36    267   DKGB_YERPE 2,5-diketo-D-gluconic acid reducta...2429e-19     87.4     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050580; F:2,5-didehydrogluconate reductase activity; IEA:EC.
GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:UniProtKB-KW.
145P76234    284   YEAE_ECOLI Uncharacterized protein yeaE OS=Es...2914e-18     85.5     27     46
GO:0016491; F:oxidoreductase activity; IEA:InterPro.
146P82809    322   AK1CD_MESAU Aldo-keto reductase family 1 memb...2936e-18     85.9     28     46
GO:0050109; F:morphine 6-dehydrogenase activity; IEA:EC.
GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW.
147Q5RJP0    316   ALD1_RAT Aldose reductase-related protein 1 O...3032e-16     81.6     29     46
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:RGD.
148P42972    300   YCSN_BACSU Uncharacterized oxidoreductase Ycs...2530.00000000000002     75.9     27     43
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
149C6TBN2    346   AKR1_SOYBN Probable aldo-keto reductase 1 OS=...2690.0000000000005     72     25     46
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
150F4HPY8    330   AKR6_ARATH Probable aldo-keto reductase 6 OS=...2500.000000000007     68.6     26     47
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
151Q09923    340   YAKC_SCHPO Aldo-keto reductase yakc [NADP(+)]...1440.0000000001     65.1     31     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IDA:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.
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