UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL122W

Length:

809

Number of sequences:

5887

Description:

YDL122W UBP1 SGDID:S000002280, Chr IV from 242552-244981, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	Q6A4J8	1103	UBP7_MOUSE Ubiquitin carboxyl-terminal hydrol...	130	0.93	37	26	42	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
152	Q93009	1102	UBP7_HUMAN Ubiquitin carboxyl-terminal hydrol...	130	0.96	37	26	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
153	Q4VSI4	1103	UBP7_RAT Ubiquitin carboxyl-terminal hydrolas...	130	0.96	37	26	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
									GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:RGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
154	Q9D9M2	370	UBP12_MOUSE Ubiquitin carboxyl-terminal hydro...	26	1	36.2	62	69
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
155	Q93008	2570	USP9X_HUMAN Probable ubiquitin carboxyl-termi...	223	1	37	24	43	GO:0005737; C:cytoplasm; IDA:UniProtKB.
									GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007292; P:female gamete generation; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
156	A5D9H7	369	UBP12_BOVIN Ubiquitin carboxyl-terminal hydro...	26	1	36.2	62	69
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
157	Q01477	912	UBP3_YEAST Ubiquitin carboxyl-terminal hydrol...	160	1	36.6	26	44	GO:0005737; C:cytoplasm; IC:SGD.
									GO:0003729; F:mRNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
									GO:0016579; P:protein deubiquitination; IDA:SGD.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0047484; P:regulation of response to osmotic stress; IMP:SGD.::GO:0034517; P:ribophagy; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
158	C0HB46	372	UBP12_SALSA Ubiquitin carboxyl-terminal hydro...	26	1.1	36.2	62	69
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
159	A4FUN7	371	UBP12_DANRE Ubiquitin carboxyl-terminal hydro...	26	1.1	36.2	62	69
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
160	A5WWB0	370	UBP46_DANRE Ubiquitin carboxyl-terminal hydro...	68	2.9	34.7	31	46
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0007610; P:behavior; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0032228; P:regulation of synaptic transmission, GABAergic; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
161	Q5RBQ4	366	UBP46_PONAB Ubiquitin carboxyl-terminal hydro...	68	2.2	35	31	46
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0007610; P:behavior; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0032228; P:regulation of synaptic transmission, GABAergic; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
162	P62069	366	UBP46_MOUSE Ubiquitin carboxyl-terminal hydro...	68	2.2	35	31	46
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0007610; P:behavior; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
163	P62068	366	UBP46_HUMAN Ubiquitin carboxyl-terminal hydro...	68	2.2	35	31	46
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0007610; P:behavior; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0032228; P:regulation of synaptic transmission, GABAergic; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
164	Q9FPS2	661	UBP25_ARATH Ubiquitin carboxyl-terminal hydro...	50	1.2	36.2	40	56
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
165	Q9HFS7	796	UBP4_KLULA Ubiquitin carboxyl-terminal hydrol...	59	2.1	35.8	34	46	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
166	P36026	717	UBP11_YEAST Ubiquitin carboxyl-terminal hydro...	294	4.3	34.7	22	39
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
167	Q6NTR6	690	UP44A_XENLA Ubiquitin carboxyl-terminal hydro...	88	1.3	36.2	28	51	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
168	B8NSV5	755	CREB_ASPFN Probable ubiquitin carboxyl-termin...	66	1.5	36.2	39	53
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
169	P70398	2559	USP9X_MOUSE Probable ubiquitin carboxyl-termi...	223	1.5	36.2	24	43	GO:0045177; C:apical part of cell; IDA:MGI.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0070410; F:co-SMAD binding; ISS:BHF-UCL.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
170	Q2UUG8	754	CREB_ASPOR Probable ubiquitin carboxyl-termin...	66	1.5	36.2	39	53
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
									GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
171	Q5XGZ2	690	UP44B_XENLA Ubiquitin carboxyl-terminal hydro...	88	1.6	35.8	28	51	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051322; P:anaphase; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
172	Q70EK9	711	UBP51_HUMAN Ubiquitin carboxyl-terminal hydro...	30	2.2	35.4	47	67
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
173	O94782	785	UBP1_HUMAN Ubiquitin carboxyl-terminal hydrol...	191	1.7	35.8	26	38	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
									GO:0006281; P:DNA repair; TAS:Reactome.::GO:0035520; P:monoubiquitinated protein deubiquitination; IMP:UniProtKB.::GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
174	P50101	1230	UBP15_YEAST Ubiquitin carboxyl-terminal hydro...	50	1.7	36.2	36	50	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
									GO:0016579; P:protein deubiquitination; IC:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
175	A6ZY34	926	UBP4_YEAS7 Ubiquitin carboxyl-terminal hydrol...	63	3.7	35	35	54	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
176	P09846	865	RPOA1_METTW DNA-directed RNA polymerase subun...	132	1.7	35.8	28	42
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
177	Q6U7I1	1101	UBP7_CHICK Ubiquitin carboxyl-terminal hydrol...	46	1.7	35.8	37	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
									GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
178	P32571	926	UBP4_YEAST Ubiquitin carboxyl-terminal hydrol...	63	3.6	35	35	54	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000502; C:proteasome complex; IPI:SGD.
									GO:0004175; F:endopeptidase activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:SGD.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
									GO:0006897; P:endocytosis; IMP:SGD.::GO:0010995; P:free ubiquitin chain depolymerization; IDA:SGD.::GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006275; P:regulation of DNA replication; IMP:SGD.::GO:0010992; P:ubiquitin homeostasis; IMP:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
179	B3LGK1	926	UBP4_YEAS1 Ubiquitin carboxyl-terminal hydrol...	63	3.6	35	35	54	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
180	Q9USM5	849	UBP1_SCHPO Probable ubiquitin carboxyl-termin...	30	1.8	35.8	43	67	GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
									GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
181	Q9VYQ8	1129	UBP7_DROME Ubiquitin carboxyl-terminal hydrol...	54	2	35.8	35	52	GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0043234; C:protein complex; IPI:FlyBase.::GO:0035328; C:transcriptionally silent chromatin; IDA:FlyBase.
									GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
									GO:0006342; P:chromatin silencing; IGI:FlyBase.::GO:0016578; P:histone deubiquitination; IDA:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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