Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL120W
Length:
174
Number of sequences:
5887
Description:
YDL120W YFH1 SGDID:S000002278, Chr IV from 245923-246447, Genome Release 64-1-1, Verified ORF, "Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog is mutated in Friedrich's ataxia"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q07540    174   FRDA_YEAST Frataxin homolog, mitochondrial OS...1747e-128     363     100     100GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; IDA:SGD.
GO:0008198; F:ferrous iron binding; IDA:SGD.::GO:0004322; F:ferroxidase activity; IDA:SGD.::GO:0034986; F:iron chaperone activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.::GO:0006749; P:glutathione metabolic process; IMP:SGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.::GO:0006121; P:mitochondrial electron transport, succinate to ubiquinone; IMP:UniProtKB.::GO:0010040; P:response to iron(II) ion; IMP:UniProtKB.::GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
2O74831    158   FRDA_SCHPO Frataxin homolog, mitochondrial OS...1032e-19     84.7     45     61GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0030234; F:enzyme regulator activity; ISS:PomBase.::GO:0004322; F:ferroxidase activity; IEA:EC.::GO:0005506; F:iron ion binding; ISS:PomBase.
GO:0006879; P:cellular iron ion homeostasis; ISS:PomBase.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0018283; P:iron incorporation into metallo-sulfur cluster; ISS:PomBase.::GO:0072592; P:oxygen metabolic process; ISS:PomBase.
3Q54C45    193   FRDA_DICDI Frataxin, mitochondrial OS=Dictyos...965e-19     84.7     46     64GO:0005739; C:mitochondrion; ISS:dictyBase.
GO:0030234; F:enzyme regulator activity; ISS:dictyBase.::GO:0008198; F:ferrous iron binding; ISS:dictyBase.::GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0006879; P:cellular iron ion homeostasis; ISS:dictyBase.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0018283; P:iron incorporation into metallo-sulfur cluster; ISS:dictyBase.
4Q9TY03    136   FRDA_CAEEL Frataxin, mitochondrial OS=Caenorh...1242e-18     82     37     56GO:0005739; C:mitochondrion; IDA:WormBase.
GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0042542; P:response to hydrogen peroxide; IMP:WormBase.::GO:0000303; P:response to superoxide; IMP:WormBase.
5Q9W385    190   FRDA_DROME Frataxin homolog, mitochondrial OS...1084e-18     82     44     57GO:0005739; C:mitochondrion; IMP:FlyBase.
GO:0004322; F:ferroxidase activity; IEA:EC.::GO:0034986; F:iron chaperone activity; IDA:FlyBase.
GO:0019896; P:axon transport of mitochondrion; IDA:FlyBase.::GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0051881; P:regulation of mitochondrial membrane potential; IDA:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.
6O35943    207   FRDA_MOUSE Frataxin, mitochondrial OS=Mus mus...1022e-17     80.9     42     63GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0009060; P:aerobic respiration; IMP:MGI.::GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:MGI.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0007005; P:mitochondrion organization; IMP:MGI.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IMP:MGI.::GO:0006119; P:oxidative phosphorylation; IMP:MGI.::GO:0019230; P:proprioception; IMP:MGI.
7Q8HXX9    210   FRDA_MACFA Frataxin, mitochondrial OS=Macaca ...1013e-17     80.1     43     61GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
8Q16595    210   FRDA_HUMAN Frataxin, mitochondrial OS=Homo sa...1013e-17     80.1     43     61GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005759; C:mitochondrial matrix; ISS:BHF-UCL.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:BHF-UCL.::GO:0008199; F:ferric iron binding; IDA:BHF-UCL.::GO:0008198; F:ferrous iron binding; IDA:BHF-UCL.::GO:0004322; F:ferroxidase activity; IDA:UniProtKB.::GO:0034986; F:iron chaperone activity; IDA:BHF-UCL.
GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.::GO:0006783; P:heme biosynthetic process; NAS:BHF-UCL.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0018283; P:iron incorporation into metallo-sulfur cluster; IDA:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0051349; P:positive regulation of lyase activity; IDA:UniProtKB.::GO:0048554; P:positive regulation of metalloenzyme activity; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IMP:BHF-UCL.::GO:0051347; P:positive regulation of transferase activity; IMP:BHF-UCL.::GO:0016540; P:protein autoprocessing; IDA:BHF-UCL.::GO:0010722; P:regulation of ferrochelatase activity; IDA:BHF-UCL.::GO:0010039; P:response to iron ion; IMP:BHF-UCL.
9Q05B87    217   FRDA_BOVIN Frataxin, mitochondrial OS=Bos tau...1011e-16     78.2     42     61GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.
10Q9ZR07    187   FRDA_ARATH Frataxin, mitochondrial OS=Arabido...1070.000000000000002     74.3     37     61GO:0005739; C:mitochondrion; ISS:TAIR.
GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0009060; P:aerobic respiration; IMP:TAIR.::GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0042542; P:response to hydrogen peroxide; IMP:TAIR.
11Q8SWI3    118   FRDA_ENCCU Frataxin, mitosomal OS=Encephalito...1140.0000000000004     66.6     33     55GO:0032047; C:mitosome; IEA:UniProtKB-SubCell.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
12D3ZYW7    208   FRDA_RAT Frataxin, mitochondrial OS=Rattus no...1020.0000000000006     67.4     35     58GO:0005739; C:mitochondrion; IDA:RGD.
GO:0019899; F:enzyme binding; IPI:RGD.::GO:0004322; F:ferroxidase activity; IEA:EC.
GO:0006879; P:cellular iron ion homeostasis; NAS:RGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
13Q92IH7    103   CYAY_RICCN Protein CyaY OS=Rickettsia conorii...780.000000000009     62.8     44     60
GO:0004322; F:ferroxidase activity; IEA:InterPro.
14C3PN35    103   CYAY_RICAE Protein CyaY OS=Rickettsia africae...780.000000000009     62.8     44     60
GO:0004322; F:ferroxidase activity; IEA:InterPro.
15A8GRM5    103   CYAY_RICRS Protein CyaY OS=Rickettsia rickett...780.00000000003     60.8     42     60
GO:0004322; F:ferroxidase activity; IEA:InterPro.
16B0BX32    103   CYAY_RICRO Protein CyaY OS=Rickettsia rickett...780.00000000003     60.8     42     60
GO:0004322; F:ferroxidase activity; IEA:InterPro.
17C4K1X9    103   CYAY_RICPU Protein CyaY OS=Rickettsia peacock...780.00000000004     60.8     42     60
GO:0004322; F:ferroxidase activity; IEA:InterPro.
18A8GN05    101   CYAY_RICAH Protein CyaY OS=Rickettsia akari (...960.0000000001     59.3     38     59
GO:0004322; F:ferroxidase activity; IEA:InterPro.
19Q1RIC4    96   CYAY_RICBR Protein CyaY OS=Rickettsia bellii ...900.0000000002     58.9     38     60
20Q9ZDK5    104   CYAY_RICPR Protein CyaY OS=Rickettsia prowaze...790.0000000002     58.5     41     63
21Q68X49    104   CYAY_RICTY Protein CyaY OS=Rickettsia typhi (...790.0000000003     58.2     41     63
22C5BBD2    107   CYAY_EDWI9 Protein CyaY OS=Edwardsiella ictal...840.0000000004     57.8     42     52
23Q4UM50    101   CYAY_RICFE Protein CyaY OS=Rickettsia felis (...780.0000000008     57     40     60GO:0005739; C:mitochondrion; IEA:InterPro.
GO:0004322; F:ferroxidase activity; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; IEA:InterPro.
24C3LPW5    104   CYAY_VIBCM Protein CyaY OS=Vibrio cholerae se...970.000000001     56.2     35     56
25Q9KVL8    104   CYAY_VIBCH Protein CyaY OS=Vibrio cholerae se...970.000000001     56.2     35     56
26A5F4I9    104   CYAY_VIBC3 Protein CyaY OS=Vibrio cholerae se...970.000000001     56.2     35     56
27B7VMD7    104   CYAY_VIBSL Protein CyaY OS=Vibrio splendidus ...970.000000005     54.7     34     58
28B3QSI5    105   CYAY_CHLT3 Protein CyaY OS=Chloroherpeton tha...830.000000009     53.9     31     59
29A7MQK4    106   CYAY_CROS8 Protein CyaY OS=Cronobacter sakaza...950.00000001     53.9     35     54
30A9L5F8    109   CYAY_SHEB9 Protein CyaY OS=Shewanella baltica...970.00000001     53.5     30     53
31A6WTF8    109   CYAY_SHEB8 Protein CyaY OS=Shewanella baltica...970.00000001     53.5     30     53
records
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