rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q07533 | 885 | CYK3_YEAST Cytokinesis protein 3 OS=Saccharom... | 885 | 0 | 1834 | 100 | 100 | GO:0000142; C:cellular bud neck contractile ring; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IPI:SGD. | 2 | O14302 | 886 | CYK3_SCHPO cytokinesis protein 3 OS=Schizosac... | 540 | 2e-45 | 179 | 26 | 43 | GO:0005826; C:actomyosin contractile ring; NAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; NAS:PomBase. | 3 | Q8AXU9 | 353 | SH3G3_CHICK Endophilin-A3 OS=Gallus gallus (C... | 55 | 0.003 | 44.3 | 40 | 65 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 4 | Q557J6 | 481 | DBNL_DICDI Drebrin-like protein OS=Dictyostel... | 59 | 0.011 | 42.7 | 37 | 56 | GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:dictyBase.::GO:0032037; F:myosin I heavy chain binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0031269; P:pseudopodium assembly; IMP:dictyBase. | 5 | Q8AXV1 | 353 | SH3G2_CHICK Endophilin-A1 OS=Gallus gallus (C... | 55 | 0.019 | 42 | 40 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 6 | Q99962 | 352 | SH3G2_HUMAN Endophilin-A1 OS=Homo sapiens (Hu... | 55 | 0.019 | 42 | 40 | 65 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome. | 7 | Q62420 | 352 | SH3G2_MOUSE Endophilin-A1 OS=Mus musculus (Mo... | 55 | 0.021 | 41.6 | 40 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002090; P:regulation of receptor internalization; IDA:MGI.::GO:0048488; P:synaptic vesicle endocytosis; IGI:MGI. | 8 | Q6NRD3 | 826 | SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF... | 57 | 0.023 | 42.4 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 9 | O35179 | 352 | SH3G2_RAT Endophilin-A1 OS=Rattus norvegicus ... | 55 | 0.026 | 41.6 | 40 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q28E95 | 861 | SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF... | 57 | 0.029 | 42 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 11 | Q8AXV0 | 367 | SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C... | 56 | 0.03 | 41.2 | 39 | 61 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 12 | Q9Z0R4 | 1714 | ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo... | 92 | 2.8 | 35.4 | 23 | 47 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 13 | Q9URW6 | 430 | YIE2_SCHPO SH3 domain-containing protein PJ69... | 60 | 0.038 | 41.2 | 35 | 60 | GO:0030479; C:actin cortical patch; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase. | 14 | Q71F54 | 894 | SH3R1_RAT E3 ubiquitin-protein ligase SH3RF1 ... | 57 | 0.041 | 41.2 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006917; P:induction of apoptosis; IMP:RGD. | 15 | A5D8S5 | 867 | SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF... | 57 | 0.043 | 41.2 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 16 | B0BNA1 | 340 | SH3Y1_RAT SH3 domain-containing YSC84-like pr... | 64 | 0.043 | 40.8 | 39 | 52 | | | | | | | | | | | | | | | | | | | | | | 17 | O35180 | 347 | SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ... | 52 | 0.045 | 40.8 | 40 | 67 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 18 | Q69ZI1 | 892 | SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF... | 57 | 0.045 | 41.2 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046328; P:regulation of JNK cascade; IDA:MGI. | 19 | Q62421 | 347 | SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo... | 52 | 0.048 | 40.8 | 40 | 67 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 20 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 57 | 0.05 | 41.2 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | Q96HL8 | 342 | SH3Y1_HUMAN SH3 domain-containing YSC84-like ... | 66 | 0.052 | 40.4 | 36 | 52 | | | | | | | | | | | | | | | | | | | | | | 22 | Q5RAQ2 | 342 | SH3Y1_PONAB SH3 domain-containing YSC84-like ... | 66 | 0.055 | 40.4 | 36 | 52 | | | | | | | | | | | | | | | | | | | | | | 23 | Q7Z6J0 | 888 | SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF... | 57 | 0.059 | 40.8 | 35 | 61 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB. | 24 | Q92608 | 1830 | DOCK2_HUMAN Dedicator of cytokinesis protein ... | 67 | 0.06 | 40.8 | 31 | 51 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0042608; F:T cell receptor binding; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 25 | Q2KJA1 | 368 | SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi... | 63 | 0.061 | 40.4 | 38 | 57 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 26 | Q5RBR0 | 888 | SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF... | 57 | 0.062 | 40.8 | 35 | 61 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 27 | O43125 | 296 | CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce... | 59 | 0.073 | 40 | 41 | 58 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 28 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 65 | 3.4 | 35 | 26 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. | 29 | Q91X43 | 789 | SH319_MOUSE SH3 domain-containing protein 19 ... | 58 | 0.08 | 40.4 | 36 | 59 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 30 | Q5XXR3 | 772 | ARHG6_RAT Rho guanine nucleotide exchange fac... | 53 | 0.08 | 40.4 | 40 | 62 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 31 | Q15052 | 776 | ARHG6_HUMAN Rho guanine nucleotide exchange f... | 80 | 0.083 | 40.4 | 36 | 55 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. |