rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 174 | 0.0000006 | 53.9 | 26 | 49 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 362 | P21898 | 254 | ADH_DROHE Alcohol dehydrogenase OS=Drosophila... | 241 | 0.0000007 | 53.1 | 26 | 45 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 363 | Q6P3L6 | 319 | DH12A_DANRE Estradiol 17-beta-dehydrogenase 1... | 224 | 0.0000007 | 53.5 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 364 | A2QCH3 | 346 | MKAR_ASPNC 3-ketoacyl-CoA reductase OS=Asperg... | 200 | 0.0000007 | 53.5 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 365 | A9UM79 | 311 | DRS7C_XENTR Dehydrogenase/reductase SDR famil... | 107 | 0.0000007 | 53.5 | 25 | 55 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 366 | P23278 | 254 | ADH_DROSL Alcohol dehydrogenase OS=Drosophila... | 241 | 0.0000007 | 53.1 | 27 | 44 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 367 | Q5RCF8 | 278 | DHRS4_PONAB Dehydrogenase/reductase SDR famil... | 196 | 0.0000007 | 53.5 | 25 | 46 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 368 | P10807 | 254 | ADH_DROLE Alcohol dehydrogenase OS=Drosophila... | 240 | 0.0000007 | 53.1 | 27 | 44 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 369 | O08699 | 266 | PGDH_RAT 15-hydroxyprostaglandin dehydrogenas... | 196 | 0.0000007 | 53.1 | 24 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 370 | Q9NKW1 | 441 | MFEA_DICDI Peroxisomal multifunctional enzyme... | 183 | 0.0000007 | 53.9 | 23 | 45 | GO:0005777; C:peroxisome; TAS:dictyBase. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 371 | Q02338 | 343 | BDH_HUMAN D-beta-hydroxybutyrate dehydrogenas... | 190 | 0.0000009 | 53.5 | 24 | 46 | GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.::GO:0046952; P:ketone body catabolic process; TAS:Reactome. | 372 | O88451 | 316 | RDH7_MOUSE Retinol dehydrogenase 7 OS=Mus mus... | 194 | 0.0000009 | 53.1 | 23 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC. | | | | | | | | | | | 373 | Q4X117 | 345 | MKAR_ASPFU 3-ketoacyl-CoA reductase OS=A1100)... | 199 | 0.000001 | 53.1 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 374 | B0XSI3 | 345 | MKAR_ASPFC 3-ketoacyl-CoA reductase OS=(Asper... | 199 | 0.000001 | 53.1 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 375 | O32291 | 356 | YXNA_BACSU Uncharacterized oxidoreductase yxn... | 227 | 0.000001 | 53.1 | 20 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 376 | Q5RCU5 | 277 | CBR1_PONAB Carbonyl reductase [NADPH] 1 OS=Po... | 137 | 0.000001 | 52.4 | 26 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 377 | Q9XT00 | 259 | DHB8_PIG Estradiol 17-beta-dehydrogenase 8 OS... | 212 | 0.000001 | 52.4 | 24 | 46 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 378 | O57314 | 312 | DHB12_ANAPL Estradiol 17-beta-dehydrogenase 1... | 213 | 0.000001 | 52.8 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 379 | P25143 | 281 | ADHR_DROAM Alcohol dehydrogenase-related 31 k... | 193 | 0.000001 | 52.4 | 24 | 47 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 380 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 204 | 0.000001 | 52.8 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 381 | Q9BTZ2 | 278 | DHRS4_HUMAN Dehydrogenase/reductase SDR famil... | 196 | 0.000001 | 52.4 | 24 | 46 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.::GO:0018455; F:alcohol dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.::GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; IDA:UniProtKB.] | 382 | P0AET8 | 255 | HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogena... | 198 | 0.000002 | 52 | 27 | 45 | GO:0005829; C:cytosol; IDA:UniProtKB. | | | | | | | | | | GO:0008709; F:cholate 7-alpha-dehydrogenase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 383 | P0AET9 | 255 | HDHA_ECO57 7-alpha-hydroxysteroid dehydrogena... | 198 | 0.000002 | 52 | 27 | 45 | | | | | | | | | | | GO:0008709; F:cholate 7-alpha-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 384 | A6NNS2 | 312 | DRS7C_HUMAN Dehydrogenase/reductase SDR famil... | 108 | 0.000002 | 52.4 | 28 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 385 | A5E0R1 | 350 | MKAR_LODEL 3-ketoacyl-CoA reductase OS=NBRC 1... | 261 | 0.000002 | 52.4 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 386 | Q8AVY8 | 318 | DH12B_XENLA Estradiol 17-beta-dehydrogenase 1... | 176 | 0.000002 | 52.4 | 26 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 387 | P22245 | 254 | ADH_DRODI Alcohol dehydrogenase OS=Drosophila... | 241 | 0.000002 | 52 | 25 | 45 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. | 388 | Q7Z9I4 | 253 | YCP6_SCHPO Uncharacterized oxidoreductase C66... | 197 | 0.000002 | 52 | 22 | 43 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 389 | A8N6B4 | 339 | MKAR_COPC7 3-ketoacyl-CoA reductase OS=9003) ... | 188 | 0.000002 | 52.4 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 390 | Q6UX07 | 377 | DHR13_HUMAN Dehydrogenase/reductase SDR famil... | 213 | 0.000002 | 52.4 | 22 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 391 | P21518 | 254 | ADH_DROAF Alcohol dehydrogenase OS=Drosophila... | 238 | 0.000002 | 51.6 | 26 | 46 | | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IEA:InterPro. |