Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL108W
Length:
306
Number of sequences:
5887
Description:
YDL108W KIN28 SGDID:S000002266, Chr IV from 267698-267725,267807-268699, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721O22040    666   ANP1_ARATH Mitogen-activated protein kinase k...2905e-21     97.4     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
722Q9N0X0    344   AURKB_PIG Aurora kinase B OS=Sus scrofa (Pig)...2975e-21     94.7     26     44GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
723Q38868    541   CDPK9_ARATH Calcium-dependent protein kinase ...3055e-21     96.7     27     43GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; TAS:TAIR.
724Q54MV2    715   MRKB_DICDI Probable serine/threonine-protein ...2025e-21     97.4     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
725P28523    332   CSK2A_MAIZE Casein kinase II subunit alpha OS...3166e-21     94.4     27     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
726Q9LZW4    442   CIPKE_ARATH CBL-interacting serine/threonine-...2046e-21     95.9     32     49GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
727Q5EG47    559   AAPK1_MOUSE 5'-AMP-activated protein kinase c...2956e-21     96.7     26     46GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0035174; F:histone serine kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0019395; P:fatty acid oxidation; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; IDA:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
728Q54R82    942   MKKA_DICDI Mitogen-activated protein kinase k...2056e-21     97.4     27     51GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
729O88643    545   PAK1_MOUSE Serine/threonine-protein kinase PA...2957e-21     96.3     26     46GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042060; P:wound healing; ISS:UniProtKB.
730O45818    1070   DKF2_CAEEL Serine/threonine-protein kinase dk...2797e-21     97.4     27     46GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0045089; P:positive regulation of innate immune response; IMP:WormBase.
731Q8CFH6    931   SIK2_MOUSE Serine/threonine-protein kinase SI...1928e-21     97.1     32     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0008286; P:insulin receptor signaling pathway; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IDA:UniProtKB.
732Q3E9C0    523   CDPKY_ARATH Calcium-dependent protein kinase ...2988e-21     95.9     28     45GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
733P92937    421   CIPKF_ARATH CBL-interacting serine/threonine-...2219e-21     95.1     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR.
734O94806    890   KPCD3_HUMAN Serine/threonine-protein kinase D...2089e-21     97.1     33     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.
GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
735Q556S2    513   PAKH_DICDI Serine/threonine-protein kinase pa...2879e-21     95.9     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
736Q9I9E0    898   TAOK3_CHICK Serine/threonine-protein kinase T...2541e-20     96.7     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:AgBase.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:AgBase.::GO:0046329; P:negative regulation of JNK cascade; ISS:AgBase.::GO:0046330; P:positive regulation of JNK cascade; ISS:AgBase.::GO:0046777; P:protein autophosphorylation; ISS:AgBase.
737A5GFW1    402   AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)...2381e-20     94.7     28     48GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
738P28567    151   CDC22_PEA Cell division control protein 2 hom...1371e-20     90.9     36     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
739Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...2901e-20     95.5     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
740Q54CY9    313   MYLKD_DICDI Probable myosin light chain kinas...2961e-20     93.6     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
741P93759    530   CDPKE_ARATH Calcium-dependent protein kinase ...3071e-20     95.9     25     45GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
742Q9QYZ5    504   SMK3_MOUSE Sperm motility kinase 3 OS=Mus mus...1931e-20     95.5     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
743Q53UA7    898   TAOK3_RAT Serine/threonine-protein kinase TAO...2901e-20     96.7     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.
744Q7L7X3    1001   TAOK1_HUMAN Serine/threonine-protein kinase T...2031e-20     96.7     31     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
745Q8NE63    616   HIPK4_HUMAN Homeodomain-interacting protein k...2191e-20     95.9     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
746O88664    1001   TAOK1_RAT Serine/threonine-protein kinase TAO...2031e-20     96.7     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030295; F:protein kinase activator activity; IMP:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB.
747Q5F2E8    1001   TAOK1_MOUSE Serine/threonine-protein kinase T...2031e-20     96.7     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
748Q6P2M8    343   KCC1B_HUMAN Calcium/calmodulin-dependent prot...2841e-20     93.6     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
749Q9XTF3    817   MBK2_CAEEL Dual specificity tyrosine-phosphor...3271e-20     96.3     25     45GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0005694; C:chromosome; IDA:WormBase.::GO:0043186; C:P granule; IDA:WormBase.
GO:0005524; F:ATP binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; ISS:WormBase.
GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0000281; P:cytokinesis after mitosis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:WormBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:WormBase.::GO:0045732; P:positive regulation of protein catabolic process; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0046777; P:protein autophosphorylation; ISS:WormBase.
750Q9H0K1    926   SIK2_HUMAN Serine/threonine-protein kinase SI...1921e-20     96.7     32     53GO:0005794; C:Golgi apparatus; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
751Q5F3L1    789   KS6A5_CHICK Ribosomal protein S6 kinase alpha...2200.00000000004     67     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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