Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL108W
Length:
306
Number of sequences:
5887
Description:
YDL108W KIN28 SGDID:S000002266, Chr IV from 267698-267725,267807-268699, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601O00444    970   PLK4_HUMAN Serine/threonine-protein kinase PL...1939e-23     103     33     56GO:0005814; C:centriole; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
602P13234    474   KCC4_RAT Calcium/calmodulin-dependent protein...1919e-23     101     36     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.
603P92958    512   KIN11_ARATH SNF1-related protein kinase catal...1959e-23     101     31     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
604Q91YA2    424   KPSH1_MOUSE Serine/threonine-protein kinase H...2981e-22     100     30     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
605Q8BI55    632   DYRK4_MOUSE Dual specificity tyrosine-phospho...2211e-22     102     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
606Q9V3D5    722   DYRK2_DROME Dual specificity tyrosine-phospho...3031e-22     102     27     46GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0042048; P:olfactory behavior; IMP:FlyBase.
607P59241    397   AURKA_RAT Aurora kinase A OS=Rattus norvegicu...2411e-22     100     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
608Q0JI49    502   CIPKB_ORYSJ CBL-interacting protein kinase 11...2031e-22     101     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
609Q64702    925   PLK4_MOUSE Serine/threonine-protein kinase PL...1931e-22     102     33     56GO:0005814; C:centriole; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; IMP:UniProtKB.
610Q8SRI3    334   MRK1_ENCCU Probable serine/threonine-protein ...1621e-22     99.4     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
611Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...2161e-22     103     30     54GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
612Q16566    473   KCC4_HUMAN Calcium/calmodulin-dependent prote...1911e-22     100     36     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; IGI:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045670; P:regulation of osteoclast differentiation; TAS:UniProtKB.::GO:0033081; P:regulation of T cell differentiation in thymus; TAS:UniProtKB.
613Q95ZQ4    626   AAPK2_CAEEL 5'-AMP-activated protein kinase c...3081e-22     101     26     48GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.
GO:0004679; F:AMP-activated protein kinase activity; IDA:WormBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
614Q5JLD8    446   CIPK8_ORYSJ CBL-interacting protein kinase 8 ...2152e-22     100     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
615O08678    793   MARK1_RAT Serine/threonine-protein kinase MAR...2222e-22     102     31     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; NAS:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:RGD.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
616Q9FJ55    483   CIPKJ_ARATH CBL-interacting serine/threonine-...1972e-22     100     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
617Q7Z8E9    914   STE20_MAGO7 Serine/threonine-protein kinase M...2312e-22     102     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
618A3B529    435   CIPKS_ORYSJ CBL-interacting protein kinase 28...2032e-22     99.8     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
619P28829    659   BYR2_SCHPO Protein kinase byr2 OS=Schizosacch...2252e-22     101     30     52GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; TAS:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
620Q8VHJ5    795   MARK1_MOUSE Serine/threonine-protein kinase M...2222e-22     101     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0070300; F:phosphatidic acid binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
621Q5JLS2    540   CIPKC_ORYSJ CBL-interacting protein kinase 12...2942e-22     100     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
622Q5W736    457   CIPKI_ORYSJ CBL-interacting protein kinase 18...2192e-22     99.8     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
623Q05512    776   MARK2_MOUSE Serine/threonine-protein kinase M...2183e-22     101     31     49GO:0045180; C:basal cortex; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
624Q9STV4    445   CIPK8_ARATH CBL-interacting serine/threonine-...2043e-22     99.4     29     52GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009749; P:response to glucose stimulus; TAS:TAIR.::GO:0010167; P:response to nitrate; IEP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
625Q54YF2    727   AMPKA_DICDI 5'-AMP-activated serine/threonine...2033e-22     101     30     57
GO:0004679; F:AMP-activated protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006754; P:ATP biosynthetic process; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0007005; P:mitochondrion organization; IMP:dictyBase.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
626P34101    595   FHKC_DICDI Probable serine/threonine-protein ...3113e-22     100     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
627Q9SEZ7    469   CIPKG_ARATH CBL-interacting serine/threonine-...2083e-22     99.8     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
628P28582    532   CDPK_DAUCA Calcium-dependent protein kinase O...3033e-22     100     27     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
629Q9C098    648   DCLK3_HUMAN Serine/threonine-protein kinase D...2924e-22     100     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
630P25323    295   MYLKA_DICDI Myosin light chain kinase A OS=Di...3044e-22     97.8     26     46GO:0005737; C:cytoplasm; IDA:dictyBase.
GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IDA:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.
631P97477    395   AURKA_MOUSE Aurora kinase A OS=Mus musculus (...2414e-22     98.6     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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