Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL108W
Length:
306
Number of sequences:
5887
Description:
YDL108W KIN28 SGDID:S000002266, Chr IV from 267698-267725,267807-268699, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q39019    421   KSG10_ARATH Shaggy-related protein kinase kap...3084e-44     160     35     52GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
332Q0D0P5    364   HOG1_ASPTN Mitogen-activated protein kinase h...2995e-44     159     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
333Q13164    816   MK07_HUMAN Mitogen-activated protein kinase 7...3065e-44     164     33     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IGI:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IGI:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
334Q8W4J2    567   MPK16_ARATH Mitogen-activated protein kinase ...2986e-44     162     37     53GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
335Q9TVL3    478   CDK9_CAEEL Probable cyclin-dependent kinase 9...3356e-44     161     31     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
336Q4FCZ5    450   SSN3_GIBMO Serine/threonine-protein kinase SS...3486e-44     161     31     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
337Q5XIT0    507   CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R...2846e-44     162     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
338Q702W0    400   HOG1_BLAAD Mitogen-activated protein kinase h...2999e-44     159     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
339P53778    367   MK12_HUMAN Mitogen-activated protein kinase 1...3081e-43     159     32     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0045445; P:myoblast differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
340P43294    443   MHK_ARATH Serine/threonine-protein kinase MHK...2931e-43     160     34     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
341Q6CR51    593   SSN3_KLULA Serine/threonine-protein kinase SS...2891e-43     162     36     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
342Q9QUK0    568   CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS...2841e-43     162     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
343Q5I6M2    329   HOG1_SETTU Mitogen-activated protein kinase H...2841e-43     157     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
344Q9WVS8    806   MK07_MOUSE Mitogen-activated protein kinase 7...3061e-43     163     33     51GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0045765; P:regulation of angiogenesis; IMP:MGI.
345P90866    588   CDK8_CAEEL Cyclin-dependent kinase 8 OS=Caeno...3262e-43     161     33     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
346P0C865    806   MK07_RAT Mitogen-activated protein kinase 7 O...3062e-43     163     33     51GO:0005634; C:nucleus; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
347Q9FVS6    420   KSG4_ARATH Shaggy-related protein kinase delt...3082e-43     159     34     52GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006972; P:hyperosmotic response; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
348P51138    411   MSK2_MEDSA Glycogen synthase kinase-3 homolog...3082e-43     159     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
349Q0CQK1    435   SSN3_ASPTN Serine/threonine-protein kinase ss...3432e-43     159     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
350P30285    303   CDK4_MOUSE Cyclin-dependent kinase 4 OS=Mus m...2982e-43     156     34     49GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0007165; P:signal transduction; IDA:MGI.
351Q6BM25    472   SSN3_DEBHA Serine/threonine-protein kinase SS...2794e-43     159     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
352Q9I958    361   MK14B_CYPCA Mitogen-activated protein kinase ...2994e-43     157     32     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
353P35426    303   CDK4_RAT Cyclin-dependent kinase 4 OS=Rattus ...2985e-43     155     34     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045787; P:positive regulation of cell cycle; TAS:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0045793; P:positive regulation of cell size; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010288; P:response to lead ion; IMP:RGD.::GO:0033574; P:response to testosterone stimulus; IDA:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
354Q40518    409   MSK1_TOBAC Shaggy-related protein kinase NtK-...3105e-43     157     34     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
355Q39012    407   KSG9_ARATH Shaggy-related protein kinase iota...3127e-43     157     33     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009742; P:brassinosteroid mediated signaling pathway; IPI:TAIR.::GO:0042538; P:hyperosmotic salinity response; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0032880; P:regulation of protein localization; IDA:TAIR.
356C4YGK0    415   ERK1_CANAW Extracellular signal-regulated kin...3168e-43     157     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
357Q2GYV9    512   SSN3_CHAGB Serine/threonine-protein kinase SS...2728e-43     159     35     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
358Q39010    412   KSG6_ARATH Shaggy-related protein kinase zeta...3129e-43     157     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009742; P:brassinosteroid mediated signaling pathway; IPI:TAIR.::GO:0032880; P:regulation of protein localization; IDA:TAIR.
359Q5A1D3    422   ERK1_CANAL Extracellular signal-regulated kin...2301e-42     157     36     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0000747; P:conjugation with cellular fusion; IMP:CGD.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IMP:CGD.
360O76039    1030   CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS...2821e-42     162     33     54GO:0032839; C:dendrite cytoplasm; ISS:BHF-UCL.::GO:0044294; C:dendritic growth cone; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:HGNC.
GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
GO:0001764; P:neuron migration; ISS:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.::GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
361Q6C4M9    386   HOG1_YARLI Mitogen-activated protein kinase H...2991e-42     156     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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