Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL108W
Length:
306
Number of sequences:
5887
Description:
YDL108W KIN28 SGDID:S000002266, Chr IV from 267698-267725,267807-268699, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q5E9Y0    298   CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos t...2912e-72     232     41     60GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:AgBase.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; ISS:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:AgBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:AgBase.::GO:0006813; P:potassium ion transport; ISS:AgBase.
32P13863    303   CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallu...2996e-72     231     39     58GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
33O55076    298   CDK2_CRIGR Cyclin-dependent kinase 2 OS=Crice...2916e-72     230     40     60GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
34P29618    294   CDKA1_ORYSJ Cyclin-dependent kinase A-1 OS=Or...2918e-72     230     42     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
35Q63699    298   CDK2_RAT Cyclin-dependent kinase 2 OS=Rattus ...2911e-71     230     40     60GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IDA:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
36P24941    298   CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo ...2911e-71     229     40     60GO:0015030; C:Cajal body; IDA:UniProtKB.::GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071732; P:cellular response to nitric oxide; TAS:UniProtKB.::GO:0051298; P:centrosome duplication; TAS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000085; P:G2 phase of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.::GO:0016572; P:histone phosphorylation; IDA:GOC.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.::GO:0006275; P:regulation of DNA replication; TAS:ProtInc.::GO:0060968; P:regulation of gene silencing; IDA:UniProtKB.::GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
37Q9W739    302   CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana ...3031e-71     229     39     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
38P48963    298   CDK2_MESAU Cyclin-dependent kinase 2 OS=Mesoc...2914e-71     228     40     59GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
39Q55GS4    366   CDK10_DICDI Probable cyclin-dependent kinase ...2995e-71     230     38     62GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
40Q4Y4B1    288   CDC2H_PLACH Cell division control protein 2 h...2885e-71     228     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
41Q4KM34    346   CDK20_RAT Cyclin-dependent kinase 20 OS=Rattu...3019e-71     229     39     57GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
42Q07785    288   CDC2H_PLAFK Cell division control protein 2 h...2881e-70     226     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
43P61075    288   CDC2H_PLAF7 Cell division control protein 2 h...2881e-70     226     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
44Q9JHU3    346   CDK20_MOUSE Cyclin-dependent kinase 20 OS=Mus...3011e-70     228     39     57GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
45Q4Z6R1    288   CDC2H_PLABA Cell division control protein 2 h...2881e-70     226     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
46P46892    436   CD11B_RAT Cyclin-dependent kinase 11B OS=Ratt...2983e-70     230     40     60GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
47Q9HGY5    326   PHO85_CANAX Negative regulator of the PHO sys...2956e-70     226     39     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
48P17157    305   PHO85_YEAST Cyclin-dependent protein kinase P...3039e-70     225     39     59GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0050849; P:negative regulation of calcium-mediated signaling; IGI:SGD.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0016242; P:negative regulation of macroautophagy; IMP:SGD.::GO:0045936; P:negative regulation of phosphate metabolic process; IGI:SGD.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:SGD.::GO:0016239; P:positive regulation of macroautophagy; IMP:SGD.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IGI:SGD.::GO:0032880; P:regulation of protein localization; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.
49P29619    292   CDKA2_ORYSJ Cyclin-dependent kinase A-2 OS=Or...2899e-70     224     40     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
50Q6BRY2    330   PHO85_DEBHA Negative regulator of the PHO sys...2951e-69     226     39     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
51Q92241    304   PHO85_KLULA Negative regulator of the PHO sys...2971e-69     224     38     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
52Q9UQ88    783   CD11A_HUMAN Cyclin-dependent kinase 11A OS=Ho...2922e-69     235     41     61GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0007067; P:mitosis; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; IEP:UniProtKB.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
53Q9XZD6    288   CDC2H_PLAVI Cell division control protein 2 h...2882e-69     223     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
54Q00526    305   CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo ...2973e-69     223     41     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0045023; P:G0 to G1 transition; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
55Q38772    294   CDC2A_ANTMA Cell division control protein 2 h...2915e-69     223     40     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
56P23111    294   CDC2_MAIZE Cell division control protein 2 ho...2915e-69     223     41     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007067; P:mitosis; IEA:UniProtKB-KW.
57P21127    795   CD11B_HUMAN Cyclin-dependent kinase 11B OS=Ho...2926e-69     234     41     61GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007067; P:mitosis; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; IEP:UniProtKB.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
58P93101    294   CDC2_CHERU Cell division control protein 2 ho...2916e-69     223     41     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
59P34117    292   CDK5_DICDI Cyclin-dependent kinase 5 homolog ...2907e-69     222     39     57GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0072686; C:mitotic spindle; IDA:dictyBase.::GO:0005654; C:nucleoplasm; IDA:dictyBase.::GO:0005625; C:soluble fraction; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0031157; P:regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
60Q41639    294   CDC2_VIGAC Cell division control protein 2 ho...2928e-69     222     40     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
61Q6C7U8    294   PHO85_YARLI Negative regulator of the PHO sys...2961e-68     222     40     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
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