Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL108W
Length:
306
Number of sequences:
5887
Description:
YDL108W KIN28 SGDID:S000002266, Chr IV from 267698-267725,267807-268699, Genome Release 64-1-1, Verified ORF, "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q95NE7    360   MK14_PANTR Mitogen-activated protein kinase 1...2993e-45     162     33     51GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
302Q8SQW2    329   CTK1_ENCCU Probable CTD kinase subunit alpha ...3053e-45     162     34     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
303A2QRF6    365   HOG1_ASPNC Mitogen-activated protein kinase h...2993e-45     162     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
304Q6CCB0    405   SSN3_YARLI Serine/threonine-protein kinase SS...3123e-45     163     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
305Q39011    380   KSG7_ARATH Shaggy-related protein kinase eta ...3124e-45     162     34     53GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009742; P:brassinosteroid mediated signaling pathway; IMP:TAIR.::GO:0009729; P:detection of brassinosteroid stimulus; IMP:TAIR.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0009825; P:multidimensional cell growth; IMP:TAIR.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.
306Q9DGE2    361   MK14A_DANRE Mitogen-activated protein kinase ...3044e-45     162     32     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0040016; P:embryonic cleavage; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0001756; P:somitogenesis; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
307Q53N72    498   MPK15_ORYSJ Mitogen-activated protein kinase ...3024e-45     165     37     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
308Q9Y7W4    746   BUR1_CANAL Serine/threonine-protein kinase BU...3185e-45     167     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0030448; P:hyphal growth; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.
309P0C661    612   CDK8_CAEBR Cyclin-dependent kinase 8 OS=Caeno...3335e-45     166     34     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
310Q9Z1B7    366   MK13_MOUSE Mitogen-activated protein kinase 1...2975e-45     162     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
311O94737    370   MAPK1_PNECA Mitogen-activated protein kinase ...2915e-45     162     35     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043008; F:ATP-dependent protein binding; IPI:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0016043; P:cellular component organization; IMP:UniProtKB.::GO:0040010; P:positive regulation of growth rate; IMP:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
312Q5VP69    501   MPK16_ORYSJ Mitogen-activated protein kinase ...2929e-45     164     36     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
313Q17446    377   PMK1_CAEEL Mitogen-activated protein kinase p...2921e-44     161     32     52GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:WormBase.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0012501; P:programmed cell death; IMP:WormBase.
314Q3T0N5    366   MK13_BOVIN Mitogen-activated protein kinase 1...3001e-44     161     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
315Q63538    367   MK12_RAT Mitogen-activated protein kinase 12 ...3031e-44     161     32     52GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
316Q09892    349   HOG1_SCHPO Mitogen-activated protein kinase s...2981e-44     160     32     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0071243; P:cellular response to arsenic-containing substance; IMP:PomBase.::GO:0071473; P:cellular response to cation stress; IGI:PomBase.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0034644; P:cellular response to UV; TAS:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; IGI:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0031990; P:mRNA export from nucleus in response to heat stress; IMP:PomBase.::GO:0045931; P:positive regulation of mitotic cell cycle; IGI:PomBase.::GO:0034504; P:protein localization to nucleus; IMP:PomBase.::GO:0043949; P:regulation of cAMP-mediated signaling; IMP:PomBase.::GO:0010847; P:regulation of chromatin assembly; IMP:PomBase.::GO:0010848; P:regulation of chromatin disassembly; IMP:PomBase.::GO:0051101; P:regulation of DNA binding; IDA:PomBase.::GO:0035065; P:regulation of histone acetylation; IMP:PomBase.::GO:0010520; P:regulation of reciprocal meiotic recombination; IMP:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0070321; P:regulation of translation in response to nitrogen starvation; IDA:PomBase.::GO:0043557; P:regulation of translation in response to osmotic stress; IDA:PomBase.::GO:0043556; P:regulation of translation in response to oxidative stress; IDA:PomBase.::GO:0051595; P:response to methylglyoxal; IDA:PomBase.::GO:0051403; P:stress-activated MAPK cascade; TAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
317Q9C9U4    576   MPK15_ARATH Mitogen-activated protein kinase ...3021e-44     164     38     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
318A3LUB9    431   SSN3_PICST Serine/threonine-protein kinase SS...2951e-44     162     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
319O08911    367   MK12_MOUSE Mitogen-activated protein kinase 1...3032e-44     160     32     52GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
320Q8TD08    544   MK15_HUMAN Mitogen-activated protein kinase 1...3072e-44     164     33     51GO:0005576; C:extracellular region; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; NAS:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
321A5PKJ4    781   MK07_BOVIN Mitogen-activated protein kinase 7...3062e-44     165     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
322O13958    369   SSN3_SCHPO Serine/threonine-protein kinase sr...3092e-44     160     31     50GO:0016592; C:mediator complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
323P11802    303   CDK4_HUMAN Cyclin-dependent kinase 4 OS=Homo ...2982e-44     159     35     50GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.::GO:0042493; P:response to drug; IGI:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
324Q38HL5    366   HOG1_EURHE Mitogen-activated protein kinase h...2992e-44     160     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
325Q9WUI1    364   MK11_MOUSE Mitogen-activated protein kinase 1...2953e-44     160     31     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
326Q15759    364   MK11_HUMAN Mitogen-activated protein kinase 1...2953e-44     160     31     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
327O62618    366   MK14A_DROME Mitogen-activated protein kinase ...3013e-44     160     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; TAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0008348; P:negative regulation of antimicrobial humoral response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0080134; P:regulation of response to stress; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0006970; P:response to osmotic stress; IDA:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
328P39073    555   SSN3_YEAST Meiotic mRNA stability protein kin...2903e-44     163     34     53GO:0016592; C:mediator complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:SGD.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0060258; P:negative regulation of filamentous growth; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:SGD.::GO:0000435; P:positive regulation of transcription from RNA polymerase II promoter by galactose; IMP:SGD.::GO:0031648; P:protein destabilization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
329Q9DGE1    348   MK14B_DANRE Mitogen-activated protein kinase ...2993e-44     159     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
330Q6L5F7    582   MPK17_ORYSJ Mitogen-activated protein kinase ...2984e-44     163     36     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
331Q39019    421   KSG10_ARATH Shaggy-related protein kinase kap...3084e-44     160     35     52GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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