Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL101C
Length:
513
Number of sequences:
5887
Description:
YDL101C DUN1 SGDID:S000002259, Chr IV from 281848-280307, Genome Release 64-1-1, reverse complement, Verified ORF, "Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871Q9M1Z5    393   MPK10_ARATH Mitogen-activated protein kinase ...3165e-24     107     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
872Q96PY6    1258   NEK1_HUMAN Serine/threonine-protein kinase Ne...2825e-24     110     27     48GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
873Q55A09    1331   Y9963_DICDI Probable serine/threonine-protein...2845e-24     110     29     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
874Q08942    431   NRKA_TRYBB Putative serine/threonine-protein ...2916e-24     107     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
875A8X0C4    649   PAR4_CAEBR Serine/threonine-protein kinase pa...3316e-24     109     30     45GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
876P51955    445   NEK2_HUMAN Serine/threonine-protein kinase Ne...2886e-24     107     28     45GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051299; P:centrosome separation; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
877Q61RA2    493   CHK1_CAEBR Serine/threonine-protein kinase ch...3246e-24     108     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
878Q8BGW6    398   ST32A_MOUSE Serine/threonine-protein kinase 3...2936e-24     107     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
879Q6PA14    485   STK4_XENLA Serine/threonine-protein kinase 4 ...3326e-24     108     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
880Q0CL79    1342   SEPH_ASPTN Cytokinesis protein sepH OS=Asperg...2986e-24     109     32     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
881Q6PFQ0    740   KS6A6_DANRE Ribosomal protein S6 kinase alpha...3087e-24     109     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
882Q9UK32    745   KS6A6_HUMAN Ribosomal protein S6 kinase alpha...3057e-24     109     29     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
883Q8QHK8    426   MK08_XENLA Mitogen-activated protein kinase 8...3187e-24     107     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
884Q9Y2H1    464   ST38L_HUMAN Serine/threonine-protein kinase 3...3707e-24     107     24     42GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
885Q8RXT4    555   NEK4_ARATH Serine/threonine-protein kinase Ne...2907e-24     108     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
886Q5VP69    501   MPK16_ORYSJ Mitogen-activated protein kinase ...3467e-24     108     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
887Q17850    572   PAK1_CAEEL Serine/threonine-protein kinase pa...2897e-24     108     28     48GO:0030424; C:axon; IDA:WormBase.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; IDA:WormBase.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IGI:WormBase.::GO:0035262; P:gonad morphogenesis; IMP:WormBase.::GO:0031581; P:hemidesmosome assembly; IGI:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.
888P48734    297   CDK1_BOVIN Cyclin-dependent kinase 1 OS=Bos t...3137e-24     105     28     48GO:0030496; C:midbody; ISS:AgBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0005876; C:spindle microtubule; ISS:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
889A7F0W2    951   ATG1_SCLS1 Serine/threonine-protein kinase AT...2547e-24     109     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
890Q75KK8    542   MPK14_ORYSJ Mitogen-activated protein kinase ...3477e-24     108     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
891Q55C57    473   GLKA_DICDI Probable serine/threonine-protein ...3138e-24     107     30     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; ISS:dictyBase.
892A1DES4    377   MPKC_NEOFI Mitogen-activated protein kinase m...3098e-24     106     30     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
893Q9XZD6    288   CDC2H_PLAVI Cell division control protein 2 h...3138e-24     105     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
894P34112    296   CDK1_DICDI Cyclin-dependent kinase 1 OS=Dicty...3078e-24     105     32     47GO:0005622; C:intracellular; IDA:dictyBase.
GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
895Q4G3H4    758   IKKA_DANRE Inhibitor of nuclear factor kappa-...2348e-24     108     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008384; F:IkappaB kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:ZFIN.
GO:0007417; P:central nervous system development; IMP:ZFIN.::GO:0055113; P:epiboly involved in gastrulation with mouth forming second; IMP:ZFIN.::GO:0043066; P:negative regulation of apoptotic process; IMP:ZFIN.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:ZFIN.::GO:0001757; P:somite specification; IMP:ZFIN.
896Q8T0S6    669   HIPPO_DROME Serine/threonine-protein kinase h...3459e-24     108     27     43GO:0016020; C:membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:FlyBase.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:FlyBase.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase.
897A1CAF0    380   MPKC_ASPCL Mitogen-activated protein kinase m...3109e-24     106     31     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
898Q4P5N0    746   STE20_USTMA Serine/threonine-protein kinase S...2849e-24     108     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
899O75676    772   KS6A4_HUMAN Ribosomal protein S6 kinase alpha...2991e-23     108     27     48GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0048273; F:mitogen-activated protein kinase p38 binding; IGI:UniProtKB.::GO:0004711; F:ribosomal protein S6 kinase activity; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043987; P:histone H3-S10 phosphorylation; IMP:UniProtKB.::GO:0043988; P:histone H3-S28 phosphorylation; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001818; P:negative regulation of cytokine production; TAS:UniProtKB.::GO:0032793; P:positive regulation of CREB transcription factor activity; TAS:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
900P06493    297   CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo ...3131e-23     105     28     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0007098; P:centrosome cycle; TAS:UniProtKB.::GO:0006281; P:DNA repair; TAS:UniProtKB.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0007344; P:pronuclear fusion; TAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045995; P:regulation of embryonic development; TAS:UniProtKB.::GO:0014038; P:regulation of Schwann cell differentiation; TAS:UniProtKB.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
901P36583    1016   PCK2_SCHPO Protein kinase C-like 2 OS=Schizos...2891e-23     108     28     49GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005622; C:intracellular; IC:GOC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IC:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
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