Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL080C
Length:
609
Number of sequences:
5887
Description:
YDL080C THI3 SGDID:S000002238, Chr IV from 312471-310642, Genome Release 64-1-1, reverse complement, Verified ORF, "Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q07471    609   THI3_YEAST Thiamine metabolism regulatory pro...6090     1272     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0016831; F:carboxy-lyase activity; IMP:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0070623; P:regulation of thiamine biosynthetic process; IMP:SGD.
2Q6FJA3    564   PDC1_CANGA Pyruvate decarboxylase OS=NRRL Y-6...5560     627     52     73
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
3P06169    563   PDC1_YEAST Pyruvate decarboxylase isozyme 1 O...5560     624     52     73GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IDA:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0019655; P:glucose catabolic process to ethanol; IDA:SGD.::GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006090; P:pyruvate metabolic process; IDA:SGD.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.
4P33149    564   PDC1_KLUMA Pyruvate decarboxylase OS=Kluyvero...5560     623     52     72
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
5P34734    564   PDC_HANUV Pyruvate decarboxylase OS=Hansenias...5550     617     50     72
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
6Q12629    563   PDC1_KLULA Pyruvate decarboxylase OS=1267 / N...5560     616     51     72
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
7P16467    563   PDC5_YEAST Pyruvate decarboxylase isozyme 2 O...5570     605     51     72GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IDA:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0019655; P:glucose catabolic process to ethanol; IDA:SGD.::GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006090; P:pyruvate metabolic process; IDA:SGD.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.
8P26263    563   PDC6_YEAST Pyruvate decarboxylase isozyme 3 O...5610     597     51     72GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IMP:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IEA:UniProtKB-KW.::GO:0006067; P:ethanol metabolic process; IMP:SGD.::GO:0006559; P:L-phenylalanine catabolic process; IEA:UniProtKB-KW.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.
9P83779    567   PDC1_CANAL Pyruvate decarboxylase OS=Candida ...5710     589     49     69GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030446; C:hyphal cell wall; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD.::GO:0005625; C:soluble fraction; IDA:CGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
10Q2UKV4    570   PDC_ASPOR Pyruvate decarboxylase OS=Aspergill...5595e-162     483     41     64
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
11Q4WXX9    569   PDC_ASPFU Pyruvate decarboxylase OS=A1100) (A...5592e-157     470     42     63
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
12Q0CNV1    569   PDC_ASPTN Pyruvate decarboxylase OS=Aspergill...5593e-156     468     40     63
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
13P87208    568   PDC_EMENI Pyruvate decarboxylase OS=194 / M13...5598e-152     456     41     61
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
14Q09737    571   PDC1_SCHPO Putative pyruvate decarboxylase C1...5736e-149     449     39     61GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; ISS:PomBase.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0000949; P:aromatic amino acid family catabolic process to alcohol via Ehrlich pathway; ISS:PomBase.::GO:0019655; P:glucose catabolic process to ethanol; ISS:PomBase.::GO:0006090; P:pyruvate metabolic process; ISS:PomBase.
15O42873    570   PDC4_SCHPO Putative pyruvate decarboxylase C3...5731e-142     432     37     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0009063; P:cellular amino acid catabolic process; ISS:PomBase.::GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006090; P:pyruvate metabolic process; NAS:PomBase.
16P51844    577   PDC_ASPPA Pyruvate decarboxylase OS=Aspergill...5661e-106     340     33     54
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
17Q9CBD6    569   KDC_MYCLE Alpha-keto-acid decarboxylase OS=My...5558e-97     313     31     50
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
18A0QBE6    563   KDC_MYCA1 Alpha-keto-acid decarboxylase OS=My...5532e-96     313     32     51
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
19Q742Q2    563   KDC_MYCPA Alpha-keto-acid decarboxylase OS=My...5532e-96     313     32     51
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
20P23234    552   DCIP_ENTCL Indole-3-pyruvate decarboxylase OS...5601e-95     310     32     52
GO:0047434; F:indolepyruvate decarboxylase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
21O53865    560   KDC_MYCTU Alpha-keto-acid decarboxylase OS=My...5516e-94     306     32     51GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
22A5U0P1    560   KDC_MYCTA Alpha-keto-acid decarboxylase OS=My...5516e-94     306     32     51
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
23A1KGY5    560   KDC_MYCBP Alpha-keto-acid decarboxylase OS=My...5516e-94     306     32     51
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
24Q7U140    560   KDC_MYCBO Alpha-keto-acid decarboxylase OS=My...5516e-94     306     32     51
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
25A0PL16    566   KDC_MYCUA Alpha-keto-acid decarboxylase OS=My...5648e-94     306     32     51
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
26A0R480    555   KDC_MYCS2 Alpha-keto-acid decarboxylase OS=My...5511e-85     284     31     50
GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
27Q06408    635   ARO10_YEAST Transaminated amino acid decarbox...5996e-79     268     31     51GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0050177; F:phenylpyruvate decarboxylase activity; IDA:SGD.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006559; P:L-phenylalanine catabolic process; IDA:SGD.::GO:0006552; P:leucine catabolic process; IMP:SGD.::GO:0000951; P:methionine catabolic process to 3-methylthiopropanol; IMP:SGD.::GO:0006569; P:tryptophan catabolic process; IEA:UniProtKB-KW.::GO:0006572; P:tyrosine catabolic process; IEA:UniProtKB-KW.
28A2Y5L9    605   PDC1_ORYSI Pyruvate decarboxylase isozyme 1 O...5604e-67     236     29     49
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
29Q0DHF6    605   PDC1_ORYSJ Pyruvate decarboxylase isozyme 1 O...5601e-66     234     29     49
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
30A2XFI3    606   PDC2_ORYSI Pyruvate decarboxylase isozyme 2 O...5613e-66     233     28     48
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
31Q10MW3    605   PDC2_ORYSJ Pyruvate decarboxylase isozyme 2 O...5611e-65     231     28     48
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
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