UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL080C

Length:

609

Number of sequences:

5887

Description:

YDL080C THI3 SGDID:S000002238, Chr IV from 312471-310642, Genome Release 64-1-1, reverse complement, Verified ORF, "Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q41769	638	ILVB2_MAIZE Acetolactate synthase 2, chloropl...	516	0.00000008	58.9	22	37	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009635; P:response to herbicide; IEA:UniProtKB-KW.
92	P39994	560	YEC0_YEAST Putative 2-hydroxyacyl-CoA lyase O...	509	0.0000001	58.2	24	41	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
93	P20906	528	MDLC_PSEPU Benzoylformate decarboxylase OS=Ps...	489	0.0000002	57.8	21	38
									GO:0050695; F:benzoylformate decarboxylase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0018924; P:mandelate metabolic process; IEA:UniProtKB-KW.
94	Q93PS3	584	XSC_DESTI Sulfoacetaldehyde acetyltransferase...	507	0.0000003	57	22	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0050487; F:sulfoacetaldehyde acetyltransferase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0019529; P:taurine catabolic process; IEA:InterPro.
95	P0AEP7	593	GCL_ECOLI Glyoxylate carboligase OS=Escherich...	497	0.000004	53.5	20	36
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0009028; F:tartronate-semialdehyde synthase activity; IDA:EcoCyc.::GO:0030976; F:thiamine pyrophosphate binding; IDA:EcoCyc.
									GO:0046296; P:glycolate catabolic process; IMP:EcoCyc.::GO:0009436; P:glyoxylate catabolic process; IMP:EcoCyc.
96	P0AEP8	593	GCL_ECO57 Glyoxylate carboligase OS=Escherich...	497	0.000004	53.5	20	36
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0009028; F:tartronate-semialdehyde synthase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009436; P:glyoxylate catabolic process; IEA:InterPro.
97	P07003	572	POXB_ECOLI Pyruvate dehydrogenase [ubiquinone...	577	0.000004	53.5	21	39	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0052737; F:pyruvate dehydrogenase (quinone) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
98	Q84H41	603	XSC_ALCXX Sulfoacetaldehyde acetyltransferase...	510	0.00002	51.2	19	37	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0050487; F:sulfoacetaldehyde acetyltransferase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0019529; P:taurine catabolic process; IEA:InterPro.
99	Q54DA9	580	HACL1_DICDI Probable 2-hydroxyacyl-CoA lyase ...	528	0.00004	50.1	22	37	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
100	A5YBJ6	642	IOLD_LACCA 3D-(3,5/4)-trihydroxycyclohexane-1...	403	0.0002	48.1	20	37
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
101	P37063	603	POXB_LACPL Pyruvate oxidase OS=Lactobacillus ...	447	0.0002	48.1	20	38
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0047112; F:pyruvate oxidase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
102	P0CH62	589	CHDH_AZOSP Cyclohexane-1,2-dione hydrolase OS...	386	0.0002	48.1	22	39
103	Q723S8	638	IOLD_LISMF 3D-(3,5/4)-trihydroxycyclohexane-1...	100	0.85	36.2	27	42
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
104	Q898E8	644	IOLD_CLOTE 3D-(3,5/4)-trihydroxycyclohexane-1...	438	0.0004	47	20	37
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
105	Q5WKY8	637	IOLD_BACSK 3D-(3,5/4)-trihydroxycyclohexane-1...	435	0.0004	47	22	39
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
106	Q65D03	637	IOLD_BACLD 3D-(3,5/4)-trihydroxycyclohexane-1...	413	0.0005	46.6	23	38
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
107	P51853	563	BZNB_PSEFL Benzaldehyde lyase OS=Pseudomonas ...	438	0.0005	46.6	19	36
									GO:0047695; F:benzoin aldolase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
108	Q8Y9Y1	638	IOLD_LISMO 3D-(3,5/4)-trihydroxycyclohexane-1...	433	0.0006	46.6	22	36
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
109	A7ZAH8	637	IOLD_BACA2 3D-(3,5/4)-trihydroxycyclohexane-1...	420	0.001	45.4	24	38
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
110	P42415	637	IOLD_BACSU 3D-(3,5/4)-trihydroxycyclohexane-1...	417	0.001	45.4	24	38
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
111	P40149	568	OXC_OXAFO Oxalyl-CoA decarboxylase OS=Oxaloba...	102	0.002	45.1	31	43
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0033611; P:oxalate catabolic process; IEA:InterPro.
112	Q9HUR2	528	MDLC_PSEAE Benzoylformate decarboxylase OS=12...	390	0.006	43.1	20	39
									GO:0050695; F:benzoylformate decarboxylase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0018924; P:mandelate metabolic process; IEA:UniProtKB-KW.
113	P96591	574	YDAP_BACSU Putative thiamine pyrophosphate-co...	276	0.016	42	21	43
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
114	P27696	559	ILVB_KLEPN Acetolactate synthase, catabolic O...	532	0.021	41.6	20	39
									GO:0003984; F:acetolactate synthase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
115	Q54970	591	POXB_STRPN Pyruvate oxidase OS=Streptococcus ...	548	0.035	40.8	20	37
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0047112; F:pyruvate oxidase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro.
116	O05031	265	Y737_HAEIN Putative uncharacterized protein H...	84	0.088	38.9	32	49
									GO:0003984; F:acetolactate synthase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0009082; P:branched chain family amino acid biosynthetic process; IEA:InterPro.
117	Q92EQ4	638	IOLD_LISIN 3D-(3,5/4)-trihydroxycyclohexane-1...	410	0.089	39.7	21	39
									GO:0016823; F:hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0019310; P:inositol catabolic process; IEA:InterPro.
118	Q05326	106	PDC2_MAIZE Pyruvate decarboxylase isozyme 2 O...	89	0.09	37	30	48
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004737; F:pyruvate decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.
119	P0AFI0	564	OXC_ECOLI Probable oxalyl-CoA decarboxylase O...	68	2.2	35	29	43
									GO:0043531; F:ADP binding; IDA:EcoCyc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IDA:EcoCyc.::GO:0030976; F:thiamine pyrophosphate binding; IDA:EcoCyc.
									GO:0033611; P:oxalate catabolic process; IEA:InterPro.
120	P0AFI1	564	OXC_ECO57 Probable oxalyl-CoA decarboxylase O...	68	2.2	35	29	43
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0008949; F:oxalyl-CoA decarboxylase activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
									GO:0033611; P:oxalate catabolic process; IEA:InterPro.
121	Q9Y7M1	568	YGK4_SCHPO Putative 2-hydroxyacyl-CoA lyase O...	79	3	34.7	27	44	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.

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