Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL079C
Length:
501
Number of sequences:
5887
Description:
YDL079C MRK1 SGDID:S000002237, Chr IV from 314044-312951,314748-314337, Genome Release 64-1-1, reverse complement, Verified ORF, "Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q13164    816   MK07_HUMAN Mitogen-activated protein kinase 7...3194e-34     140     30     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IGI:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IGI:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IGI:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
272Q8TD08    544   MK15_HUMAN Mitogen-activated protein kinase 1...3134e-34     138     29     49GO:0005576; C:extracellular region; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; NAS:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
273A1DES4    377   MPKC_NEOFI Mitogen-activated protein kinase m...3025e-34     135     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
274O96821    288   CDC2H_PLAKH Cell division control protein 2 h...2985e-34     134     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
275Q40353    371   MMK2_MEDSA Mitogen-activated protein kinase h...3326e-34     135     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
276P25859    309   CKB11_ARATH Cyclin-dependent kinase B1-1 OS=A...3107e-34     134     31     49GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0048825; P:cotyledon development; IEP:TAIR.::GO:0042023; P:DNA endoreduplication; TAS:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010376; P:stomatal complex formation; IEP:TAIR.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.
277Q80Y86    549   MK15_MOUSE Mitogen-activated protein kinase 1...3147e-34     137     30     50GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
278Q9WVS8    806   MK07_MOUSE Mitogen-activated protein kinase 7...3191e-33     139     30     48GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0045765; P:regulation of angiogenesis; IMP:MGI.
279P0C865    806   MK07_RAT Mitogen-activated protein kinase 7 O...3191e-33     139     30     48GO:0005634; C:nucleus; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:RGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0070375; P:ERK5 cascade; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
280Q9U9Y8    634   NLK_CAEEL Serine/threonine kinase NLK OS=Caen...2962e-33     137     32     52GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001714; P:endodermal cell fate specification; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0042694; P:muscle cell fate specification; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:WormBase.
281P27638    372   SPK1_SCHPO Mitogen-activated protein kinase s...2955e-33     132     28     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IGI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; IMP:PomBase.
282O60145    398   PPK23_SCHPO Serine/threonine-protein kinase p...3035e-33     133     33     51GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
283Q84SN3    433   CDKF3_ORYSJ Cyclin-dependent kinase F-3 OS=Or...3266e-33     133     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
284Q9HG11    415   MPKC_EMENI Mitogen-activated protein kinase m...2958e-33     133     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
285Q6I5Y0    519   CDKC1_ORYSJ Cyclin-dependent kinase C-1 OS=Or...3238e-33     134     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
286Q27032    298   CDC2H_THEPA Cell division control protein 2 h...3078e-33     130     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
287Q9HGY5    326   PHO85_CANAX Negative regulator of the PHO sys...2939e-33     131     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
288C4YGK0    415   ERK1_CANAW Extracellular signal-regulated kin...2629e-33     132     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
289P54664    301   CC2H1_TRYCO Cell division control protein 2 h...3049e-33     130     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
290Q5A1D3    422   ERK1_CANAL Extracellular signal-regulated kin...2621e-32     132     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0000747; P:conjugation with cellular fusion; IMP:CGD.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IMP:CGD.
291Q26671    298   CDC2H_THEAN Cell division control protein 2 h...3071e-32     130     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
292P43068    501   MKC1_CANAX Mitogen-activated protein kinase M...3341e-32     133     31     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
293Q00859    355   MAPK_FUSSO Mitogen-activated protein kinase O...2551e-32     131     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
294Q5JK68    513   CDKC2_ORYSJ Cyclin-dependent kinase C-2 OS=Or...3181e-32     133     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
295P04551    297   CDK1_SCHPO Cyclin-dependent kinase 1 OS=Schiz...3002e-32     129     31     51GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; TAS:PomBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; TAS:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0008361; P:regulation of cell size; NAS:PomBase.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; TAS:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; NAS:PomBase.
296Q96VK3    544   BUR1_EMENI Serine/threonine-protein kinase bu...3012e-32     133     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
297O62618    366   MK14A_DROME Mitogen-activated protein kinase ...3302e-32     130     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; TAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0008348; P:negative regulation of antimicrobial humoral response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0080134; P:regulation of response to stress; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0006970; P:response to osmotic stress; IDA:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
298Q54QB1    369   ERK2_DICDI Extracellular signal-regulated kin...2963e-32     130     30     54GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; IGI:dictyBase.
299Q39024    376   MPK4_ARATH Mitogen-activated protein kinase 4...3173e-32     130     27     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0006972; P:hyperosmotic response; IMP:TAIR.::GO:0042539; P:hypotonic salinity response; IDA:TAIR.::GO:0009868; P:jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway; TAS:TAIR.::GO:0007112; P:male meiosis cytokinesis; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009409; P:response to cold; IDA:TAIR.::GO:0009620; P:response to fungus; IMP:TAIR.::GO:0009862; P:systemic acquired resistance, salicylic acid mediated signaling pathway; IMP:TAIR.
300Q8BLF2    595   CDKL3_MOUSE Cyclin-dependent kinase-like 3 OS...2934e-32     133     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
301Q4WUN7    378   MPKC_ASPFU Mitogen-activated protein kinase m...3034e-32     130     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
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