Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL074C
Length:
700
Number of sequences:
5887
Description:
YDL074C BRE1 SGDID:S000002232, Chr IV from 326149-324047, Genome Release 64-1-1, reverse complement, Verified ORF, "E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q07457    700   BRE1_YEAST E3 ubiquitin-protein ligase BRE1 O...7000     1402     100     100GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:SGD.::GO:0010390; P:histone monoubiquitination; IMP:SGD.::GO:0031573; P:intra-S DNA damage checkpoint; IMP:SGD.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:SGD.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; IMP:SGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IGI:SGD.
2Q6FWF3    693   BRE1_CANGA E3 ubiquitin-protein ligase BRE1 O...7190     621     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
3Q757D9    643   BRE1_ASHGO E3 ubiquitin-protein ligase BRE1 O...6970     545     44     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
4Q6CWM4    663   BRE1_KLULA E3 ubiquitin-protein ligase BRE1 O...7052e-174     521     44     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
5Q6BWW6    691   BRE1_DEBHA E3 ubiquitin-protein ligase BRE1 O...7191e-57     212     29     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
6Q5A4X0    681   BRE1_CANAL E3 ubiquitin-protein ligase BRE1 O...7293e-54     202     29     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030447; P:filamentous growth; IMP:CGD.
7Q6CF78    700   BRE1_YARLI E3 ubiquitin-protein ligase BRE1 O...7433e-48     184     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
8Q7S304    707   BRE1_NEUCR E3 ubiquitin-protein ligase bre-1 ...4009e-42     165     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
9Q4I7N9    703   BRE1_GIBZE E3 ubiquitin-protein ligase BRE1 O...3582e-41     164     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
10Q4WDD7    725   BRE1_ASPFU E3 ubiquitin-protein ligase bre1 O...6311e-38     156     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
11Q2U9B0    760   BRE1_ASPOR E3 ubiquitin-protein ligase bre1 O...5771e-37     153     29     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
12O74563    680   BRL2_SCHPO E3 ubiquitin-protein ligase brl2 O...6064e-28     124     26     45GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.
13P0CQ63    820   BRE1_CRYNB E3 ubiquitin-protein ligase BRE1 O...2665e-22     105     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
14P0CQ62    820   BRE1_CRYNJ E3 ubiquitin-protein ligase BRE1 O...2665e-22     105     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
15Q1MTQ0    692   BRL1_SCHPO E3 ubiquitin-protein ligase brl1 O...3601e-18     94     26     46GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033503; C:HULC complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IDA:PomBase.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEP:PomBase.
16Q8CJB9    1002   BRE1B_RAT E3 ubiquitin-protein ligase BRE1B O...3580.000000000000007     82.4     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017075; F:syntaxin-1 binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:RGD.
17Q9VRP9    1044   BRE1_DROME E3 ubiquitin-protein ligase Bre1 O...2740.00000000000001     81.6     23     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016874; F:ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016574; P:histone ubiquitination; IMP:UniProtKB.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0006513; P:protein monoubiquitination; IMP:UniProtKB.
18Q3U319    1001   BRE1B_MOUSE E3 ubiquitin-protein ligase BRE1B...2680.00000000000002     80.5     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
19O75150    1001   BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B...2680.00000000000004     80.1     24     46GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0019717; C:synaptosome; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
20Q5RAU7    1001   BRE1B_PONAB E3 ubiquitin-protein ligase BRE1B...2680.00000000000004     79.7     24     46GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
21Q4R7K7    1001   BRE1B_MACFA E3 ubiquitin-protein ligase BRE1B...2680.00000000000005     79.7     24     46GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
22Q5ZLS3    984   BRE1A_CHICK E3 ubiquitin-protein ligase BRE1A...2670.0000000000002     77.8     23     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
23A2VDP1    975   BRE1A_BOVIN E3 ubiquitin-protein ligase BRE1A...2670.0000000000004     76.6     24     48GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
24Q4P3X7    817   BRE1_USTMA E3 ubiquitin-protein ligase BRE1 O...2750.0000000000004     76.3     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
25Q5DTM8    973   BRE1A_MOUSE E3 ubiquitin-protein ligase BRE1A...2670.0000000000005     76.6     24     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
26Q5VTR2    975   BRE1A_HUMAN E3 ubiquitin-protein ligase BRE1A...2670.0000000000005     76.3     24     48GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
27A2XW69    884   BRE1A_ORYSI E3 ubiquitin-protein ligase BRE1-...2440.000000000002     74.7     25     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
28Q7XU27    884   BRE1A_ORYSJ E3 ubiquitin-protein ligase BRE1-...2440.000000000002     74.3     25     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
29Q6LFN2    1103   ZNRF1_PLAF7 RING finger protein PFF0165c OS=P...730.000000000007     72.8     41     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
30Q8RXD6    878   BRE1A_ARATH E3 ubiquitin-protein ligase BRE1-...1430.000000002     64.7     27     51GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IMP:TAIR.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.::GO:0033523; P:histone H2B ubiquitination; IMP:TAIR.::GO:0010390; P:histone monoubiquitination; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0010162; P:seed dormancy process; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
31Q86KL1    1080   BRE1_DICDI Probable E3 ubiquitin-protein liga...630.000000003     63.9     37     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
records
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