Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL074C
Length:
700
Number of sequences:
5887
Description:
YDL074C BRE1 SGDID:S000002232, Chr IV from 326149-324047, Genome Release 64-1-1, reverse complement, Verified ORF, "E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q86KL1    1080   BRE1_DICDI Probable E3 ubiquitin-protein liga...630.000000003     63.9     37     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
32Q9C895    900   BRE1B_ARATH E3 ubiquitin-protein ligase BRE1-...660.000000005     63.5     38     55GO:0005634; C:nucleus; IDA:TAIR.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; IMP:TAIR.::GO:0010390; P:histone monoubiquitination; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010162; P:seed dormancy process; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
33P34537    837   BRE1_CAEEL E3 ubiquitin-protein ligase bre-1 ...1060.0000002     58.5     30     45GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006664; P:glycolipid metabolic process; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
34Q60YN5    828   BRE1_CAEBR E3 ubiquitin-protein ligase bre-1 ...760.0000005     57     32     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
35Q336R3    844   BRE1B_ORYSJ E3 ubiquitin-protein ligase BRE1-...660.000002     55.1     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
36A2ZAC2    844   BRE1B_ORYSI E3 ubiquitin-protein ligase BRE1-...660.000002     55.1     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q6PCD5    774   RFWD3_HUMAN E3 ubiquitin-protein ligase RFWD3...570.0009     46.2     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
38D2HWM5    773   RFWD3_AILME E3 ubiquitin-protein ligase RFWD3...570.001     46.2     32     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
39Q8CIK8    774   RFWD3_MOUSE E3 ubiquitin-protein ligase RFWD3...570.001     45.8     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
40P87176    269   SLX8_SCHPO E3 ubiquitin-protein ligase comple...660.005     43.1     27     52GO:0033768; C:SUMO-targeted ubiquitin ligase complex; IPI:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000077; P:DNA damage checkpoint; IMP:PomBase.::GO:0006310; P:DNA recombination; IGI:PomBase.::GO:0033234; P:negative regulation of protein sumoylation; IMP:PomBase.
41Q753V5    1085   RAD5_ASHGO DNA repair protein RAD5 OS=Y-1056)...960.005     43.9     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
42Q75EN0    443   RAD18_ASHGO Postreplication repair E3 ubiquit...510.005     43.5     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
43Q9P6R8    533   CWC24_SCHPO Pre-mRNA-splicing factor cwf24 OS...390.006     43.5     44     56GO:0005681; C:spliceosomal complex; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; TAS:PomBase.::GO:0016074; P:snoRNA metabolic process; NAS:PomBase.
44Q02398    443   RAD18_EMENI Postreplication repair E3 ubiquit...480.007     43.1     40     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
45Q8BFW4    522   TRI65_MOUSE Tripartite motif-containing prote...470.009     42.7     32     53
GO:0008270; F:zinc ion binding; IEA:InterPro.
46Q9FF61    881   SM3L1_ARATH Putative SWI/SNF-related matrix-a...480.01     43.1     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47Q06554    1556   IRC20_YEAST Uncharacterized ATP-dependent hel...450.017     42.4     44     53GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:SGD.
48Q568Y3    192   RN185_RAT E3 ubiquitin-protein ligase RNF185 ...540.02     40.4     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
49Q5RFK9    192   RN185_PONAB E3 ubiquitin-protein ligase RNF18...540.02     40.4     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
50Q91YT2    192   RN185_MOUSE E3 ubiquitin-protein ligase RNF18...540.02     40.4     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
51Q96GF1    192   RN185_HUMAN E3 ubiquitin-protein ligase RNF18...540.02     40.4     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
52Q5ZIR9    194   RN185_CHICK E3 ubiquitin-protein ligase RNF18...540.02     40.4     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
53Q6PC78    194   RN185_DANRE E3 ubiquitin-protein ligase RNF18...540.022     40.4     30     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
54Q6FPI4    411   RAD18_CANGA Postreplication repair E3 ubiquit...510.023     41.6     35     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
55Q6CTZ8    427   RAD18_KLULA Postreplication repair E3 ubiquit...510.027     41.2     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
56O77666    545   TRI26_PIG Tripartite motif-containing protein...640.032     41.2     31     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
57Q16787    3333   LAMA3_HUMAN Laminin subunit alpha-3 OS=Homo s...5140.044     41.2     20     39GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; NAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0008544; P:epidermis development; TAS:ProtInc.::GO:0031581; P:hemidesmosome assembly; TAS:Reactome.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
58Q09463    235   RNF5_CAEEL RING finger protein 5 OS=Caenorhab...540.045     39.7     30     50GO:0030054; C:cell junction; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.::GO:0055002; P:striated muscle cell development; IMP:WormBase.
59A4IF63    744   TRIM2_BOVIN Tripartite motif-containing prote...460.049     40.8     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
60F7H9X2    744   TRIM2_CALJA Tripartite motif-containing prote...460.049     40.8     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
61D2GXS7    744   TRIM2_AILME Tripartite motif-containing prote...460.049     40.8     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
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