Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL074C
Length:
700
Number of sequences:
5887
Description:
YDL074C BRE1 SGDID:S000002232, Chr IV from 326149-324047, Genome Release 64-1-1, reverse complement, Verified ORF, "E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q3UWZ0    467   TRI75_MOUSE Tripartite motif-containing prote...553.7     34.3     33     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
212Q9ET26    229   RN114_MOUSE RING finger protein 114 OS=Mus mu...443.7     33.9     32     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
213D3ZDI6    445   MYLIP_RAT E3 ubiquitin-protein ligase MYLIP O...543.9     34.3     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0019898; C:extrinsic to membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
214Q9D4H7    753   LONF3_MOUSE LON peptidase N-terminal domain a...393.9     34.7     41     46
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
215Q6J2U6    229   RN114_RAT RING finger protein 114 OS=Rattus n...444.1     33.9     32     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
216Q28WQ1    1671   KIF1A_DROPS Kinesin-like protein unc-104 OS=D...754.1     34.7     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0048489; P:synaptic vesicle transport; ISS:UniProtKB.::GO:0047496; P:vesicle transport along microtubule; ISS:UniProtKB.
217Q9M9Y4    421   DRIP1_ARATH E3 ubiquitin protein ligase DRIP1...564.3     34.3     30     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
218Q810I1    483   TRI50_RAT E3 ubiquitin-protein ligase TRIM50 ...454.4     34.3     33     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
219Q22712    1006   MTMR3_CAEEL Myotublarin-related protein 3 OS=...834.7     34.3     24     41
GO:0016312; F:inositol bisphosphate phosphatase activity; IDA:WormBase.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:WormBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:WormBase.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045807; P:positive regulation of endocytosis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.
220Q5A4N5    378   RAD18_CANAL Postreplication repair E3 ubiquit...524.9     33.9     35     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
221Q55DU4    333   NOSIP_DICDI Nitric oxide synthase-interacting...594.9     33.9     29     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050999; P:regulation of nitric-oxide synthase activity; ISS:dictyBase.
222Q8WY64    445   MYLIP_HUMAN E3 ubiquitin-protein ligase MYLIP...545     33.9     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0019898; C:extrinsic to membrane; IEA:InterPro.
GO:0008092; F:cytoskeletal protein binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006928; P:cellular component movement; IMP:UniProtKB.::GO:0007399; P:nervous system development; IMP:UniProtKB.
223Q920B0    1035   FRM4B_MOUSE FERM domain-containing protein 4B...365.4     34.3     50     64GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IPI:MGI.
GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IGI:MGI.
224Q9CYB0    407   TRI13_MOUSE E3 ubiquitin-protein ligase TRIM1...575.5     33.9     28     44GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0097038; C:perinuclear endoplasmic reticulum; ISS:UniProtKB.
GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0016239; P:positive regulation of macroautophagy; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; ISS:UniProtKB.
225Q6J1I8    228   RN114_PIG RING finger protein 114 OS=Sus scro...445.5     33.1     30     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
226Q7YRV4    469   RO52_BOVIN E3 ubiquitin-protein ligase TRIM21...516.1     33.5     35     49GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
227Q9P3U8    468   YJ95_SCHPO Uncharacterized RING finger protei...626.2     33.5     26     44GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034080; P:CenH3-containing nucleosome assembly at centromere; ISS:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase.
228O13033    1057   RAG1_DANRE V(D)J recombination-activating pro...516.3     33.9     29     43GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
229Q95KF1    232   RN125_MACFA E3 ubiquitin-protein ligase RNF12...456.3     33.1     31     40GO:0005622; C:intracellular; IEA:InterPro.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
230Q9HCM9    518   TRI39_HUMAN Tripartite motif-containing prote...526.5     33.5     35     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
231Q1XHU0    518   TRI39_PANTR Tripartite motif-containing prote...526.7     33.5     35     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
232Q8GW10    335   BAH1L_ARATH Probable E3 ubiquitin-protein lig...526.9     33.5     33     46
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
233P26337    630   ESA8C_TRYEQ Putative adenylate cyclase regula...517     33.5     31     47
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW.
234Q32L60    407   TRI13_BOVIN E3 ubiquitin-protein ligase TRIM1...507     33.5     30     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
235Q9ESN2    488   TRI39_MOUSE Tripartite motif-containing prote...527     33.5     35     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
236Q6MFZ5    488   TRI39_RAT Tripartite motif-containing protein...527.1     33.5     35     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
237Q2KHN1    245   RN151_HUMAN RING finger protein 151 OS=Homo s...417.4     33.1     41     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
238Q61789    3333   LAMA3_MOUSE Laminin subunit alpha-3 OS=Mus mu...3447.6     33.9     24     43GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
239Q5M7V1    407   TRI13_RAT Tripartite motif-containing 13 OS=R...577.8     33.1     28     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
240Q6CSS6    229   CWC24_KLULA Pre-mRNA-splicing factor CWC24 OS...417.8     32.7     32     49GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
241Q8SQK7    439   NUF2_ENCCU Probable kinetochore protein NUF2 ...688     33.1     29     57GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
records
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