Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL074C
Length:
700
Number of sequences:
5887
Description:
YDL074C BRE1 SGDID:S000002232, Chr IV from 326149-324047, Genome Release 64-1-1, reverse complement, Verified ORF, "E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q5ACW2    216   CWC24_CANAL Pre-mRNA-splicing factor CWC24 OS...431.8     34.7     42     63GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
182Q61510    634   TRI25_MOUSE E3 ubiquitin/ISG15 ligase TRIM25 ...591.9     35.4     32     46GO:0005737; C:cytoplasm; IDA:MGI.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
183O94941    541   RNF37_HUMAN RING finger protein 37 OS=Homo sa...381.9     35.4     34     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
184Q6PCN7    1003   HLTF_MOUSE Helicase-like transcription factor...512     35.4     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
185Q9UPQ4    493   TRI35_HUMAN Tripartite motif-containing prote...602     35.4     28     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
186Q5RBG2    492   TRI35_PONAB Tripartite motif-containing prote...602.1     35.4     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
187Q6PDX6    566   RN220_MOUSE E3 ubiquitin-protein ligase Rnf22...552.1     35.4     33     53GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
188O64425    249   RMA1_ARATH E3 ubiquitin-protein ligase RMA1 O...622.2     34.7     26     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032527; P:protein exit from endoplasmic reticulum; IMP:TAIR.::GO:0032940; P:secretion by cell; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
189Q5VTB9    566   RN220_HUMAN E3 ubiquitin-protein ligase RNF22...552.2     35     33     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
190Q7M3S9    943   RNGB_DICDI RING finger protein B OS=Dictyoste...402.3     35.4     33     53GO:0005737; C:cytoplasm; TAS:dictyBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
191O88846    194   RNF4_RAT E3 ubiquitin-protein ligase RNF4 OS=...502.3     34.3     34     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:RGD.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:RGD.::GO:0031491; F:nucleosome binding; IDA:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:RGD.::GO:0032184; F:SUMO polymer binding; IPI:UniProtKB.::GO:0017025; F:TBP-class protein binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; ISS:UniProtKB.::GO:0090169; P:regulation of spindle assembly; ISS:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
192Q9LS86    480   DRIPH_ARATH Probable E3 ubiquitin protein lig...472.3     35     30     53
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
193Q8HXD5    566   RN220_MACFA E3 ubiquitin-protein ligase RNF22...552.4     35     33     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
194O75382    744   TRIM3_HUMAN Tripartite motif-containing prote...462.5     35     28     48GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
195Q867B5    1043   RAG1_PIG V(D)J recombination-activating prote...602.6     35     28     42GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
196Q1XHT8    229   TRI40_PANTR Tripartite motif-containing prote...572.6     34.3     30     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
197Q9VB08    435   RING1_DROME E3 ubiquitin-protein ligase RING1...482.7     34.7     35     48GO:0008278; C:cohesin complex; IDA:UniProtKB.::GO:0035102; C:PRC1 complex; TAS:FlyBase.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; IDA:UniProtKB.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0022008; P:neurogenesis; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0045498; P:sex comb development; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
198Q8HXH0    718   LONF3_MACFA LON peptidase N-terminal domain a...602.8     35     35     45
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
199Q92021    609   NF7B_XENLA Nuclear factor 7, brain OS=Xenopus...532.8     35     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
200Q96EX2    444   RNFT2_HUMAN RING finger and transmembrane dom...392.9     34.7     41     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
201Q496Y0    759   LONF3_HUMAN LON peptidase N-terminal domain a...602.9     35     35     45
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
202Q96A37    237   RN166_HUMAN RING finger protein 166 OS=Homo s...442.9     34.3     34     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
203Q02084    625   A33_PLEWA Zinc-binding protein A33 OS=Pleurod...453.1     34.7     36     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
204Q6J1I7    237   RN166_RAT RING finger protein 166 OS=Rattus n...443.2     34.3     34     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
205Q3U9F6    237   RN166_MOUSE RING finger protein 166 OS=Mus mu...443.2     34.3     34     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
206Q5U5Q3    659   MEX3C_HUMAN RNA-binding protein MEX3C OS=Homo...453.2     34.7     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
207Q05A36    652   MEX3C_MOUSE RNA-binding protein MEX3C OS=Mus ...453.3     34.7     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
208Q7SDY3    405   CWC24_NEUCR Pre-mRNA-splicing factor cwc-24 O...503.4     34.3     34     48GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
209Q9VUX2    1226   MIB_DROME E3 ubiquitin-protein ligase mind-bo...453.6     34.7     40     56GO:0045179; C:apical cortex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:UniProtKB.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0007423; P:sensory organ development; IMP:FlyBase.
210Q4WZJ6    418   RAD18_ASPFU Postreplication repair E3 ubiquit...393.6     34.3     36     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
211Q3UWZ0    467   TRI75_MOUSE Tripartite motif-containing prote...553.7     34.3     33     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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