Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL074C
Length:
700
Number of sequences:
5887
Description:
YDL074C BRE1 SGDID:S000002232, Chr IV from 326149-324047, Genome Release 64-1-1, reverse complement, Verified ORF, "E3 ubiquitin ligase, forms heterodimer with Rad6p to monoubiquinate histone H2B-K123, which is required for the subsequent methylation of histone H3-K4 and H3-K79; required for DSBR, transcription, silencing, and checkpoint control"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151B7HJ25    158   ISPF_BACC4 2-C-methyl-D-erythritol 2,4-cyclod...740.73     35.4     28     51
GO:0008685; F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0016114; P:terpenoid biosynthetic process; IEA:InterPro.
152B1AUE5    324   PEX10_MOUSE Peroxisome biogenesis factor 10 O...630.73     36.6     30     51GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
153P24271    1041   RAG1_CHICK V(D)J recombination-activating pro...750.76     37     29     44GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
154Q6NRE7    764   CBLBB_XENLA E3 ubiquitin-protein ligase CBL-B...430.8     36.6     33     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.
155Q6NZ21    419   RNFT1_DANRE RING finger and transmembrane dom...390.82     36.6     36     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
156Q80X56    500   TRI69_MOUSE Tripartite motif-containing prote...500.85     36.6     28     60GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
157Q24306    438   IAP1_DROME Apoptosis 1 inhibitor OS=Drosophil...540.89     36.2     35     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0019899; F:enzyme binding; IPI:FlyBase.::GO:0019788; F:NEDD8 ligase activity; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048800; P:antennal morphogenesis; IMP:FlyBase.::GO:0006916; P:anti-apoptosis; IDA:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0008407; P:chaeta morphogenesis; IMP:FlyBase.::GO:0008354; P:germ cell migration; TAS:FlyBase.::GO:0046673; P:negative regulation of compound eye retinal cell programmed cell death; IMP:FlyBase.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IGI:FlyBase.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:FlyBase.::GO:0006513; P:protein monoubiquitination; TAS:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; TAS:FlyBase.::GO:0045035; P:sensory organ precursor cell division; IGI:FlyBase.::GO:0007289; P:spermatid nucleus differentiation; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
158O60106    486   YOXA_SCHPO LON peptidase N-terminal domain an...490.9     36.2     31     45
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006508; P:proteolysis; IEA:InterPro.
159Q9UUF0    306   PEX10_SCHPO Peroxisome biogenesis factor 10 O...450.97     35.8     40     56GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
160Q17RB8    773   LONF1_HUMAN LON peptidase N-terminal domain a...390.99     36.6     41     49
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
161Q3KPU8    241   RN166_XENLA RING finger protein 166 OS=Xenopu...441     35.8     36     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
162Q14258    630   TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 ...651.1     36.2     31     43GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
163Q3UF64    445   RNFT2_MOUSE RING finger and transmembrane dom...391.1     36.2     41     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
164Q12161    406   PSH1_YEAST RING finger protein PSH1 OS=Saccha...761.2     35.8     26     42GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.
165Q9BVG3    475   TRI62_HUMAN Tripartite motif-containing prote...521.3     35.8     31     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
166Q9UTL9    1375   YIV5_SCHPO Uncharacterized ATP-dependent heli...471.3     36.2     32     45GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:PomBase.
167Q803C1    485   RNF8_DANRE E3 ubiquitin-protein ligase RNF8 O...671.3     35.8     28     46GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
168Q80V85    475   TRI62_MOUSE Tripartite motif-containing prote...521.3     35.8     31     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
169Q925F4    539   RNF37_MOUSE RING finger protein 37 OS=Mus mus...381.4     35.8     34     53GO:0005634; C:nucleus; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000209; P:protein polyubiquitination; IDA:MGI.
170Q05AK5    464   MYLIB_DANRE E3 ubiquitin-protein ligase MYLIP...551.4     35.8     33     53GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.
171Q22431    482   ARI2_CAEEL Probable protein ariadne-2 OS=Caen...351.4     35.8     40     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
172Q00174    3712   LAMA_DROME Laminin subunit alpha OS=Drosophil...3861.4     36.2     21     41GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0048854; P:brain morphogenesis; IMP:FlyBase.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007507; P:heart development; IMP:FlyBase.::GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0031987; P:locomotion involved in locomotory behavior; IMP:FlyBase.::GO:0007498; P:mesoderm development; IEP:FlyBase.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.::GO:0001964; P:startle response; IMP:FlyBase.
173Q5UP58    841   YR592_MIMIV Putative helicase R592 OS=Acantha...471.4     35.8     34     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
174Q08014    857   MEDB_GIAIN Median body protein OS=Giardia int...3201.5     35.8     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
175Q557E7    665   CBLA_DICDI E3 ubiquitin-protein ligase cblA O...631.5     35.8     33     51GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; IMP:dictyBase.::GO:0030587; P:sorocarp development; IMP:dictyBase.
176Q9Y508    228   RN114_HUMAN RING finger protein 114 OS=Homo s...441.5     35     32     48GO:0005622; C:intracellular; IDA:LIFEdb.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
177Q4U5R4    230   RN114_BOVIN RING finger protein 114 OS=Bos ta...441.6     35     32     48
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
178Q6J212    228   RN114_PANTR RING finger protein 114 OS=Pan tr...441.6     35     32     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
179P43254    675   COP1_ARATH E3 ubiquitin-protein ligase COP1 O...481.6     35.8     31     50GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000152; C:nuclear ubiquitin ligase complex; TAS:TAIR.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046283; P:anthocyanin metabolic process; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0009649; P:entrainment of circadian clock; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IGI:TAIR.::GO:0048573; P:photoperiodism, flowering; IMP:TAIR.::GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009641; P:shade avoidance; IMP:TAIR.::GO:0009647; P:skotomorphogenesis; TAS:TAIR.
180Q6P9F5    258   TRI40_HUMAN Tripartite motif-containing prote...571.8     35     30     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
181Q5ACW2    216   CWC24_CANAL Pre-mRNA-splicing factor CWC24 OS...431.8     34.7     42     63GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
records
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