UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL066W

Length:

428

Number of sequences:

5887

Description:

YDL066W IDP1 SGDID:S000002224, Chr IV from 334835-336121, Genome Release 64-1-1, Verified ORF, "Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
241	Q6TWC4	368	LEU3_SORMA 3-isopropylmalate dehydrogenase OS...	179	2.4	33.9	26	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
242	P95313	336	LEU3_MYCTU 3-isopropylmalate dehydrogenase OS...	111	2.4	33.9	25	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IDA:MTBBASE.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.
									GO:0040007; P:growth; IMP:MTBBASE.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
243	A5U706	336	LEU3_MYCTA 3-isopropylmalate dehydrogenase OS...	111	2.4	33.9	25	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
244	Q9KP82	363	LEU3_VIBCH 3-isopropylmalate dehydrogenase OS...	120	2.5	33.9	27	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
245	Q12545	380	LEU3_CEPAC 3-isopropylmalate dehydrogenase OS...	106	2.5	33.9	30	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
246	Q2JL30	371	LEU3_SYNJB 3-isopropylmalate dehydrogenase OS...	209	2.6	33.9	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
247	A1T6Z4	336	LEU3_MYCVP 3-isopropylmalate dehydrogenase OS...	111	2.7	33.9	23	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
248	P22979	199	HSP6C_DROME Heat shock protein 67B3 OS=Drosop...	97	3	33.1	25	49
									GO:0006497; P:protein lipidation; IMP:FlyBase.::GO:0010506; P:regulation of autophagy; IMP:FlyBase.::GO:0010998; P:regulation of translational initiation by eIF2 alpha phosphorylation; IMP:FlyBase.::GO:0031427; P:response to methotrexate; IEP:FlyBase.
249	Q8RDK0	355	LEU3_THETN 3-isopropylmalate dehydrogenase OS...	159	3.1	33.5	24	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
250	Q48K97	360	LEU3_PSE14 3-isopropylmalate dehydrogenase OS...	222	3.2	33.5	23	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
251	Q4FRV0	367	LEU3_PSYA2 3-isopropylmalate dehydrogenase OS...	90	3.2	33.5	29	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
252	P41560	415	IDH1_COLMA Isocitrate dehydrogenase [NADP] 1 ...	149	3.6	33.5	23	42
									GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
253	O33117	336	LEU3_MYCLE 3-isopropylmalate dehydrogenase OS...	111	3.7	33.5	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
254	B8ZS15	336	LEU3_MYCLB 3-isopropylmalate dehydrogenase OS...	111	3.7	33.5	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
255	Q2JTN8	381	LEU3_SYNJA 3-isopropylmalate dehydrogenase OS...	193	4.4	33.1	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
256	Q8EN68	366	LEU3_OCEIH 3-isopropylmalate dehydrogenase OS...	137	4.7	33.1	24	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
257	Q7V1R9	357	LEU3_PROMP 3-isopropylmalate dehydrogenase OS...	62	4.7	33.1	31	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
258	Q8ZIG9	363	LEU3_YERPE 3-isopropylmalate dehydrogenase OS...	136	4.9	33.1	29	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
259	Q88LE5	360	LEU3_PSEPK 3-isopropylmalate dehydrogenase OS...	69	5.3	32.7	28	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
260	Q5MZ40	365	LEU3_SYNP6 3-isopropylmalate dehydrogenase OS...	135	5.3	32.7	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
261	Q31N34	365	LEU3_SYNE7 3-isopropylmalate dehydrogenase OS...	135	5.3	32.7	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
262	Q96WT9	365	LEU3_SACEX 3-isopropylmalate dehydrogenase OS...	189	5.4	32.7	28	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
263	Q4QLS3	358	LEU3_HAEI8 3-isopropylmalate dehydrogenase OS...	51	5.4	32.7	35	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
264	Q2SJD6	360	LEU3_HAHCH 3-isopropylmalate dehydrogenase OS...	69	6.2	32.7	28	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
265	Q884C0	360	LEU3_PSESM 3-isopropylmalate dehydrogenase OS...	222	6.4	32.7	23	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
266	Q65V05	358	LEU3_MANSM 3-isopropylmalate dehydrogenase OS...	113	6.5	32.7	24	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
267	Q660Z6	262	COAX_BORGA Type III pantothenate kinase OS=Bo...	173	6.5	32.3	23	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004594; F:pantothenate kinase activity; IEA:EC.
									GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:InterPro.
268	Q30WD0	358	LEU3_DESDG 3-isopropylmalate dehydrogenase OS...	165	7.5	32.3	21	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
269	Q4ZUZ4	360	LEU3_PSEU2 3-isopropylmalate dehydrogenase OS...	222	7.5	32.3	23	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
270	Q48806	615	DLPA_LEGPH Protein dlpA OS=ATCC 33152 / DSM 7...	121	8.4	32.3	26	45
									GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
271	Q1QAF5	367	LEU3_PSYCK 3-isopropylmalate dehydrogenase OS...	90	9.1	32.3	28	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.

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