UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL066W

Length:

428

Number of sequences:

5887

Description:

YDL066W IDP1 SGDID:S000002224, Chr IV from 334835-336121, Genome Release 64-1-1, Verified ORF, "Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	O85064	363	LEU3_BUCAP 3-isopropylmalate dehydrogenase OS...	109	0.34	36.6	28	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
182	P50455	337	LEU3_SULTO 3-isopropylmalate dehydrogenase OS...	239	0.35	36.6	23	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
183	Q67JY2	368	LEU3_SYMTH 3-isopropylmalate dehydrogenase OS...	119	0.38	36.6	29	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
184	Q02143	345	LEU3_LACLA 3-isopropylmalate dehydrogenase OS...	223	0.4	36.6	26	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
185	Q9EVI7	364	LEU3_BUCUN 3-isopropylmalate dehydrogenase OS...	109	0.4	36.6	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
186	Q1BAR4	336	LEU3_MYCSS 3-isopropylmalate dehydrogenase OS...	111	0.42	36.2	24	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
187	A1UE98	336	LEU3_MYCSK 3-isopropylmalate dehydrogenase OS...	111	0.42	36.2	24	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
188	A3PXQ2	336	LEU3_MYCSJ 3-isopropylmalate dehydrogenase OS...	111	0.42	36.2	24	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
189	Q93714	358	IDH3A_CAEEL Probable isocitrate dehydrogenase...	101	0.42	36.6	28	46	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
190	P48572	363	LEU3_BUCRP 3-isopropylmalate dehydrogenase OS...	109	0.42	36.6	28	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
191	Q6GF15	348	LEU3_STAAR 3-isopropylmalate dehydrogenase OS...	128	0.44	36.2	27	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
192	Q31HI0	357	LEU3_THICR 3-isopropylmalate dehydrogenase OS...	134	0.48	36.2	24	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
193	P05645	365	LEU3_BACSU 3-isopropylmalate dehydrogenase OS...	191	0.5	36.2	27	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
194	O60027	372	LEU3_ASHGO 3-isopropylmalate dehydrogenase OS...	92	0.55	36.2	28	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
195	Q5YRX2	335	LEU3_NOCFA 3-isopropylmalate dehydrogenase OS...	111	0.57	35.8	26	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
196	Q9EVG3	365	LEU3_BUCML 3-isopropylmalate dehydrogenase OS...	220	0.59	35.8	25	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
197	Q9EVG9	365	LEU3_BUCUM 3-isopropylmalate dehydrogenase OS...	109	0.62	35.8	28	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
198	P43860	358	LEU3_HAEIN 3-isopropylmalate dehydrogenase OS...	132	0.65	35.8	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
199	Q9EVE1	363	LEU3_BUCUD 3-isopropylmalate dehydrogenase OS...	106	0.71	35.8	27	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
200	Q9HDQ5	359	LEU3_CANRU 3-isopropylmalate dehydrogenase OS...	168	0.78	35.4	29	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
201	Q2VZV2	369	LEU3_MAGSA 3-isopropylmalate dehydrogenase OS...	163	0.85	35.4	25	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
202	Q9EVG6	363	LEU3_BUCUA 3-isopropylmalate dehydrogenase OS...	161	0.86	35.4	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
203	Q1IZK2	351	LEU3_DEIGD 3-isopropylmalate dehydrogenase OS...	113	0.87	35.4	24	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
204	O31292	364	LEU3_BUCTS 3-isopropylmalate dehydrogenase OS...	164	0.87	35.4	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
205	Q845W3	355	LEU3_BURM1 3-isopropylmalate dehydrogenase OS...	198	0.89	35.4	24	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
206	Q757T0	839	HUL4_ASHGO Probable E3 ubiquitin-protein liga...	93	0.91	35.8	28	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
									GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
207	Q47HR1	350	LEU31_DECAR 3-isopropylmalate dehydrogenase 1...	150	0.91	35.4	23	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
208	Q2FWK2	348	LEU3_STAA8 3-isopropylmalate dehydrogenase OS...	128	0.94	35.4	27	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
209	P41926	368	LEU3_KODOH 3-isopropylmalate dehydrogenase OS...	184	1	35	26	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
210	Q3SHL3	353	LEU3_THIDA 3-isopropylmalate dehydrogenase OS...	132	1.2	35	23	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
211	P31958	357	LEU3_CLOPA 3-isopropylmalate dehydrogenase OS...	118	1.3	35	25	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.

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