Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL058W
Length:
1790
Number of sequences:
5887
Description:
YDL058W USO1 SGDID:S000002216, Chr IV from 345665-351037, Genome Release 64-1-1, Verified ORF, "Essential protein involved in the vesicle-mediated ER to Golgi transport step of secretion; binds membranes and functions during vesicle docking to the Golgi; required for assembly of the ER-to-Golgi SNARE complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q9Y6D9    718   MD1L1_HUMAN Mitotic spindle assembly checkpoi...3614.3     35.8     24     45GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005813; C:centrosome; NAS:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005819; C:spindle; NAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000090; P:mitotic anaphase; NAS:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000089; P:mitotic metaphase; NAS:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0000093; P:mitotic telophase; NAS:UniProtKB.
212Q7TT49    1713   MRCKB_RAT Serine/threonine-protein kinase MRC...5314.4     35.8     24     44GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017048; F:Rho GTPase binding; IDA:RGD.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
213Q8N1N4    520   K2C78_HUMAN Keratin, type II cytoskeletal 78 ...1074.5     35.8     26     48GO:0045095; C:keratin filament; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
214P47819    430   GFAP_RAT Glial fibrillary acidic protein OS=R...654.5     35.4     34     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005882; C:intermediate filament; NAS:RGD.
GO:0005178; F:integrin binding; IDA:MGI.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IDA:RGD.
GO:0009611; P:response to wounding; IDA:RGD.
215A9II65    1176   SMC_BORPD Chromosome partition protein Smc OS...1324.5     35.8     30     45GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
216O74689    586   NDE1_EMENI Nuclear distribution protein nudE ...1784.9     35.4     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006810; P:transport; IEA:UniProtKB-KW.
217P02542    463   DESM_CHICK Desmin OS=Gallus gallus (Chicken)....2244.9     35.4     20     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
218P70388    1312   RAD50_MOUSE DNA repair protein RAD50 OS=Mus m...7245     35.8     23     46GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0030870; C:Mre11 complex; IEA:InterPro.::GO:0045120; C:pronucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
219P97690    1191   SMC3_RAT Structural maintenance of chromosome...2065     35.8     29     50GO:0005604; C:basement membrane; IDA:RGD.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030893; C:meiotic cohesin complex; ISS:UniProtKB.::GO:0016363; C:nuclear matrix; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0045502; F:dynein binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051276; P:chromosome organization; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0006275; P:regulation of DNA replication; ISS:UniProtKB.::GO:0007165; P:signal transduction; ISS:UniProtKB.
220Q9PTD7    1360   CING_XENLA Cingulin OS=Xenopus laevis (Africa...7535.1     35.8     23     46GO:0016459; C:myosin complex; IEA:InterPro.::GO:0005923; C:tight junction; NAS:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.
221P24759    725   ATI_VACCW A-type inclusion protein OS=WR)). G...2015.1     35.4     27     49GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO:0016032; P:viral reproduction; IEA:InterPro.
222P23731    589   IFEB_ASCSU Intermediate filament protein B OS...3175.1     35.4     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
223P47037    1230   SMC3_YEAST Structural maintenance of chromoso...1805.1     35.8     28     52GO:0034990; C:nuclear mitotic cohesin complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051177; P:meiotic sister chromatid cohesion; IMP:SGD.::GO:0007064; P:mitotic sister chromatid cohesion; IGI:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0007130; P:synaptonemal complex assembly; IMP:SGD.
224Q6PA15    632   CCD22_XENLA Coiled-coil domain-containing pro...2205.2     35.4     24     48
225P03995    430   GFAP_MOUSE Glial fibrillary acidic protein OS...655.2     35.4     34     62GO:0044297; C:cell body; IDA:MGI.::GO:0042995; C:cell projection; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005882; C:intermediate filament; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0014002; P:astrocyte development; IGI:MGI.::GO:0060020; P:Bergmann glial cell differentiation; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0045109; P:intermediate filament organization; IMP:MGI.::GO:0060291; P:long-term synaptic potentiation; IMP:MGI.::GO:0010977; P:negative regulation of neuron projection development; IMP:MGI.::GO:0031102; P:neuron projection regeneration; IMP:MGI.::GO:0010625; P:positive regulation of Schwann cell proliferation; IMP:MGI.::GO:0051580; P:regulation of neurotransmitter uptake; IMP:MGI.
226Q9NSB8    354   HOME2_HUMAN Homer protein homolog 2 OS=Homo s...1055.5     35     27     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:ProtInc.
227Q8VDC1    1437   FYCO1_MOUSE FYVE and coiled-coil domain-conta...6575.7     35.4     23     45GO:0005776; C:autophagic vacuole; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0072383; P:plus-end-directed vesicle transport along microtubule; ISS:UniProtKB.
228P28023    1280   DCTN1_RAT Dynactin subunit 1 OS=Rattus norveg...2795.9     35.4     26     49GO:0005868; C:cytoplasmic dynein complex; IDA:RGD.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0008017; F:microtubule binding; NAS:RGD.::GO:0003777; F:microtubule motor activity; TAS:RGD.
GO:0007017; P:microtubule-based process; TAS:RGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
229P87169    689   MAD1_SCHPO Spindle assembly checkpoint compon...3275.9     35.4     27     49GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:PomBase.
230Q8K389    1822   CK5P2_MOUSE CDK5 regulatory subunit-associate...2785.9     35.4     28     52GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0042808; F:neuronal Cdc2-like kinase binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0007420; P:brain development; IMP:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; IMP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.
231O88801    354   HOME2_RAT Homer protein homolog 2 OS=Rattus n...1055.9     35     26     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0035256; F:G-protein coupled glutamate receptor binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IMP:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.
232Q6PH08    957   ERC2_MOUSE ERC protein 2 OS=Mus musculus (Mou...6256.1     35.4     24     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0042734; C:presynaptic membrane; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
233B1WB65    1251   CING_XENTR Cingulin OS=Xenopus tropicalis (We...4546.1     35.4     24     45GO:0016459; C:myosin complex; IEA:InterPro.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0003774; F:motor activity; IEA:InterPro.
234P35579    1960   MYH9_HUMAN Myosin-9 OS=Homo sapiens (Human). ...7646.3     35.4     24     44GO:0005826; C:actomyosin contractile ring; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0001931; C:uropod; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0030898; F:actin-dependent ATPase activity; IDA:MGI.::GO:0043531; F:ADP binding; IDA:MGI.::GO:0005524; F:ATP binding; IDA:MGI.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:UniProtKB.::GO:0043495; F:protein anchor; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0030048; P:actin filament-based movement; IDA:UniProtKB.::GO:0001525; P:angiogenesis; IDA:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043534; P:blood vessel endothelial cell migration; IMP:UniProtKB.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0050900; P:leukocyte migration; NAS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0030224; P:monocyte differentiation; IEP:UniProtKB.::GO:0030220; P:platelet formation; IMP:UniProtKB.::GO:0015031; P:protein transport; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
235Q9HK21    1140   SMC_THEAC Chromosome partition protein Smc OS...2466.4     35.4     22     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
236Q2LK54    742   COL12_CHICK Collectin-12 OS=Gallus gallus (Ch...2836.6     35.4     26     45GO:0005581; C:collagen; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
237P46864    745   ATK2_ARATH Kinesin-2 OS=Arabidopsis thaliana ...2446.6     35.4     23     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:TAIR.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
238Q4L530    639   HTRAL_STAHJ Serine protease htrA-like OS=Stap...1566.6     35     30     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
239Q07970    793   ATK1_ARATH Kinesin-1 OS=Arabidopsis thaliana ...2416.6     35.4     24     49GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005872; C:minus-end kinesin complex; TAS:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008569; F:minus-end-directed microtubule motor activity; IDA:TAIR.
GO:0009971; P:anastral spindle assembly involved in male meiosis; IMP:TAIR.::GO:0007018; P:microtubule-based movement; IEA:InterPro.
240P08964    1928   MYO1_YEAST Myosin-1 OS=Saccharomyces cerevisi...3306.8     35.4     22     46GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; ISS:SGD.
GO:0000916; P:contractile ring contraction involved in cell cycle cytokinesis; IMP:SGD.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:SGD.::GO:0007109; P:cytokinesis, completion of separation; IMP:SGD.
241Q8CDI7    1110   CC150_MOUSE Coiled-coil domain-containing pro...5177.1     35     27     46
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