Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL058W
Length:
1790
Number of sequences:
5887
Description:
YDL058W USO1 SGDID:S000002216, Chr IV from 345665-351037, Genome Release 64-1-1, Verified ORF, "Essential protein involved in the vesicle-mediated ER to Golgi transport step of secretion; binds membranes and functions during vesicle docking to the Golgi; required for assembly of the ER-to-Golgi SNARE complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P25386    1790   USO1_YEAST Intracellular protein transport pr...17900     3554     100     100GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0048211; P:Golgi vesicle docking; IDA:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0035493; P:SNARE complex assembly; IMP:SGD.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
2Q09857    1067   YAF3_SCHPO Uncharacterized protein C29E6.03c ...3630.67     38.5     26     44GO:0030134; C:ER to Golgi transport vesicle; ISS:PomBase.::GO:0000139; C:Golgi membrane; IEA:InterPro.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0035493; P:SNARE complex assembly; ISS:PomBase.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
3Q9Z1Z0    959   USO1_MOUSE General vesicular transport factor...2150.17     40.4     29     45GO:0005829; C:cytosol; IDA:MGI.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006886; P:intracellular protein transport; IDA:MGI.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
4P41541    961   USO1_BOVIN General vesicular transport factor...2302     37     27     47GO:0005829; C:cytosol; ISS:AgBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:AgBase.::GO:0048471; C:perinuclear region of cytoplasm; ISS:AgBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; ISS:AgBase.
GO:0006886; P:intracellular protein transport; ISS:AgBase.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
5O60763    962   USO1_HUMAN General vesicular transport factor...990.38     39.3     35     54GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
6P41542    959   USO1_RAT General vesicular transport factor p...2370.013     44.3     28     45GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.
GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:RGD.::GO:0045056; P:transcytosis; IDA:RGD.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
7B0F9L4    914   GOGC6_ARATH Golgin candidate 6 OS=Arabidopsis...3282e-28     128     31     54GO:0005829; C:cytosol; IDA:TAIR.::GO:0000139; C:Golgi membrane; IEA:InterPro.::GO:0005795; C:Golgi stack; IDA:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0009791; P:post-embryonic development; IMP:TAIR.::GO:0032527; P:protein exit from endoplasmic reticulum; IMP:TAIR.::GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
8O42184    1433   CLIP1_CHICK CAP-Gly domain-containing linker ...7402.2     37     26     46GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006810; P:transport; IEA:UniProtKB-KW.
9P08799    2116   MYS2_DICDI Myosin-2 heavy chain OS=Dictyostel...5760.88     38.1     26     48GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005826; C:actomyosin contractile ring; IDA:dictyBase.::GO:0032009; C:early phagosome; IDA:dictyBase.::GO:0032982; C:myosin filament; IDA:dictyBase.::GO:0016460; C:myosin II complex; IDA:dictyBase.::GO:0001931; C:uropod; IDA:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0042803; F:protein homodimerization activity; IDA:dictyBase.
GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0032060; P:bleb assembly; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0030038; P:contractile actin filament bundle assembly; IMP:dictyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IDA:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0060328; P:cytoplasmic actin-based contraction involved in forward cell motility; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0031034; P:myosin filament assembly; IDA:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0008104; P:protein localization; IMP:dictyBase.::GO:0031270; P:pseudopodium retraction; IMP:dictyBase.::GO:0034461; P:uropod retraction; IMP:dictyBase.
10Q80VJ8    578   CC155_MOUSE Coiled-coil domain-containing pro...1604.2     35.8     21     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
11P15924    2871   DESP_HUMAN Desmoplakin OS=Homo sapiens (Human...9300.015     44.3     22     43GO:0001533; C:cornified envelope; IDA:UniProtKB.::GO:0030057; C:desmosome; IEA:UniProtKB-SubCell.
GO:0030674; F:protein binding, bridging; IDA:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.::GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
12E9Q557    2883   DESP_MOUSE Desmoplakin OS=Mus musculus (Mouse...8810.00001     54.7     24     44GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0030057; C:desmosome; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0034332; P:adherens junction organization; IMP:MGI.::GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0043588; P:skin development; IMP:MGI.
13C5DY19    835   SP110_ZYGRC Spindle pole body component 110 O...2670.1     41.2     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
14Q9Y2K3    1946   MYH15_HUMAN Myosin-15 OS=Homo sapiens (Human)...4610.00002     53.9     27     44GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
15Q90339    1935   MYSS_CYPCA Myosin heavy chain, fast skeletal ...7950.32     39.7     23     46GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
16Q6URW6    2000   MYH14_MOUSE Myosin-14 OS=Mus musculus (Mouse)...6280.0001     50.8     25     45GO:0030424; C:axon; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0016459; C:myosin complex; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0030898; F:actin-dependent ATPase activity; IDA:MGI.::GO:0005524; F:ATP binding; IDA:MGI.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:MGI.
GO:0030048; P:actin filament-based movement; IDA:MGI.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
17P49025    2055   CTRO_MOUSE Citron Rho-interacting kinase OS=M...6690.042     42.7     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0033205; P:cell cycle cytokinesis; ISS:UniProtKB.::GO:0048699; P:generation of neurons; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007067; P:mitosis; IDA:UniProtKB.
18Q148H4    500   KRT81_BOVIN Keratin, type II cuticular Hb1 OS...3301.2     37.4     21     45GO:0045095; C:keratin filament; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
19P24733    1938   MYS_AEQIR Myosin heavy chain, striated muscle...9420.001     47.8     22     46GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
20Q4I877    583   NDE1_GIBZE Nuclear distribution protein nudE ...1700.46     38.9     21     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.
21P13533    1939   MYH6_HUMAN Myosin-6 OS=Homo sapiens (Human). ...10670.001     47.8     22     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005859; C:muscle myosin complex; TAS:UniProtKB.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030898; F:actin-dependent ATPase activity; IMP:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; ISS:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; IDA:HGNC.
GO:0007512; P:adult heart development; IMP:HGNC.::GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IMP:HGNC.::GO:0048739; P:cardiac muscle fiber development; ISS:BHF-UCL.::GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.::GO:0030049; P:muscle filament sliding; IMP:HGNC.::GO:0043462; P:regulation of ATPase activity; ISS:BHF-UCL.::GO:0008217; P:regulation of blood pressure; ISS:BHF-UCL.::GO:0002027; P:regulation of heart rate; IDA:HGNC.::GO:0002026; P:regulation of the force of heart contraction; ISS:BHF-UCL.::GO:0045214; P:sarcomere organization; ISS:BHF-UCL.::GO:0006941; P:striated muscle contraction; ISS:BHF-UCL.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:HGNC.::GO:0007522; P:visceral muscle development; ISS:BHF-UCL.
22P13538    1939   MYSS_CHICK Myosin heavy chain, skeletal muscl...10680.001     47.4     23     46GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
23P15241    491   K2M2_SHEEP Keratin, type II microfibrillar, c...3303.2     36.2     21     44GO:0045095; C:keratin filament; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
24Q92155    455   VIME_CYPCA Vimentin OS=Cyprinus carpio (Commo...2780.002     46.6     22     50GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
25Q02440    1829   MYO5A_CHICK Unconventional myosin-Va OS=Gallu...5460.002     47.4     24     45GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0060001; F:minus-end directed microfilament motor activity; IDA:UniProtKB.
26P78385    493   KRT83_HUMAN Keratin, type II cuticular Hb3 OS...3540.17     40.4     21     45GO:0045095; C:keratin filament; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008544; P:epidermis development; TAS:ProtInc.
27P35749    1972   MYH11_HUMAN Myosin-11 OS=Homo sapiens (Human)...5150.002     47.4     24     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005859; C:muscle myosin complex; TAS:ProtInc.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; IMP:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048739; P:cardiac muscle fiber development; IMP:UniProtKB.::GO:0048251; P:elastic fiber assembly; IMP:UniProtKB.::GO:0030241; P:skeletal muscle myosin thick filament assembly; ISS:UniProtKB.::GO:0006939; P:smooth muscle contraction; ISS:UniProtKB.
28Q8NCX0    1101   CC150_HUMAN Coiled-coil domain-containing pro...2870.002     47     30     49
29Q9USI6    1526   MYO2_SCHPO Myosin type-2 heavy chain 1 OS=Sch...5210.003     46.2     27     45GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0016460; C:myosin II complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0003779; F:actin binding; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030899; F:calcium-dependent ATPase activity; IDA:PomBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:PomBase.
GO:0071520; P:actin filament bundle convergence involved in actomyosin contractile ring formation; NAS:PomBase.
30Q5T9S5    1454   CCD18_HUMAN Coiled-coil domain-containing pro...7950.005     45.8     26     45
31P35748    1972   MYH11_RABIT Myosin-11 OS=Oryctolagus cuniculu...5170.12     41.2     24     48GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB.
GO:0048739; P:cardiac muscle fiber development; ISS:UniProtKB.::GO:0048251; P:elastic fiber assembly; ISS:UniProtKB.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IDA:UniProtKB.::GO:0006939; P:smooth muscle contraction; IDA:UniProtKB.
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