Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL047W
Length:
311
Number of sequences:
5887
Description:
YDL047W SIT4 SGDID:S000002205, Chr IV from 369771-370706, Genome Release 64-1-1, Verified ORF, "Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q0P594    309   PP2AB_BOVIN Serine/threonine-protein phosphat...3054e-133     387     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
32P48580    327   PP2A1_NEUCR Serine/threonine-protein phosphat...2855e-133     388     61     79
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
33P11611    309   PP2AB_RABIT Serine/threonine-protein phosphat...3055e-133     387     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
34P62716    309   PP2AB_RAT Serine/threonine-protein phosphatas...3055e-133     387     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.
35P62715    309   PP2AB_MOUSE Serine/threonine-protein phosphat...3055e-133     387     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; TAS:MGI.::GO:0000159; C:protein phosphatase type 2A complex; IDA:MGI.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0046677; P:response to antibiotic; IMP:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.
36P62714    309   PP2AB_HUMAN Serine/threonine-protein phosphat...3055e-133     387     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; TAS:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
37P48463    309   PP2AA_CHICK Serine/threonine-protein phosphat...3057e-133     387     58     76GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
38A8XE00    333   PP4C1_CAEBR Serine/threonine-protein phosphat...3078e-133     387     58     76GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
39Q9XGH7    312   PP2A_TOBAC Serine/threonine-protein phosphata...3055e-132     385     59     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
40P63331    309   PP2AA_RAT Serine/threonine-protein phosphatas...3117e-132     384     57     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006470; P:protein dephosphorylation; IDA:RGD.::GO:0070208; P:protein heterotrimerization; IMP:MGI.::GO:0031952; P:regulation of protein autophosphorylation; IMP:MGI.::GO:0042176; P:regulation of protein catabolic process; IMP:MGI.::GO:0010469; P:regulation of receptor activity; IMP:MGI.
41P63330    309   PP2AA_MOUSE Serine/threonine-protein phosphat...3117e-132     384     57     75GO:0000775; C:chromosome, centromeric region; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0000159; C:protein phosphatase type 2A complex; IDA:MGI.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:MGI.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:MGI.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:0006470; P:protein dephosphorylation; TAS:MGI.::GO:0051726; P:regulation of cell cycle; TAS:MGI.
42P67777    309   PP2AA_RABIT Serine/threonine-protein phosphat...3058e-132     384     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
43P67776    309   PP2AA_PIG Serine/threonine-protein phosphatas...3058e-132     384     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
44P67775    309   PP2AA_HUMAN Serine/threonine-protein phosphat...3058e-132     384     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005739; C:mitochondrion; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0000159; C:protein phosphatase type 2A complex; IDA:UniProtKB.::GO:0005625; C:soluble fraction; NAS:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0006672; P:ceramide metabolic process; NAS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000188; P:inactivation of MAPK activity; NAS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; NAS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:BHF-UCL.::GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; NAS:UniProtKB.::GO:0006275; P:regulation of DNA replication; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0030111; P:regulation of Wnt receptor signaling pathway; NAS:UniProtKB.::GO:0008380; P:RNA splicing; NAS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB.
45P67774    309   PP2AA_BOVIN Serine/threonine-protein phosphat...3058e-132     384     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
46Q10BT5    307   PP2A2_ORYSJ Serine/threonine-protein phosphat...3076e-131     382     59     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
47A2XN40    307   PP2A2_ORYSI Serine/threonine-protein phosphat...3076e-131     382     59     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
48A3C4N5    314   PP2A4_ORYSJ Serine/threonine-protein phosphat...3051e-130     381     58     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
49P0C5D7    315   PP2A4_ORYSI Putative serine/threonine-protein...3051e-130     381     58     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
50Q9XTT8    321   PP4C2_CAEEL Serine/threonine-protein phosphat...2882e-130     381     63     76
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0035188; P:hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.
51Q06009    313   PP2A_MEDSA Serine/threonine-protein phosphata...3105e-130     380     57     73
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
52Q8X178    328   PP2A2_ERYGR Serine/threonine-protein phosphat...2857e-130     380     61     77
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
53P11493    293   PP2AB_PIG Serine/threonine-protein phosphatas...2998e-130     379     58     75GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
54O74789    348   YOU5_SCHPO Putative serine/threonine-protein ...3259e-130     380     55     70GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; ISS:PomBase.
GO:0006470; P:protein dephosphorylation; IC:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
55P23696    309   PP2A_DROME Serine/threonine-protein phosphata...3051e-129     379     57     75GO:0005737; C:cytoplasm; IDA:FlyBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019208; F:phosphatase regulator activity; IDA:FlyBase.::GO:0004722; F:protein serine/threonine phosphatase activity; IMP:FlyBase.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0055059; P:asymmetric neuroblast division; IGI:FlyBase.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0007059; P:chromosome segregation; IMP:FlyBase.::GO:0090162; P:establishment of epithelial cell polarity; IEP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045880; P:positive regulation of smoothened signaling pathway; IGI:FlyBase.::GO:0006470; P:protein dephosphorylation; IMP:FlyBase.::GO:0007465; P:R7 cell fate commitment; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0009416; P:response to light stimulus; IGI:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase.
56P23636    322   PP2A2_SCHPO Major serine/threonine-protein ph...3051e-129     379     56     74GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045930; P:negative regulation of mitotic cell cycle; IGI:PomBase.::GO:0006470; P:protein dephosphorylation; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
57O04951    307   PP2A5_ARATH Serine/threonine-protein phosphat...3058e-129     376     57     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:2000012; P:regulation of auxin polar transport; IMP:TAIR.
58P48578    313   PP2A3_ARATH Serine/threonine-protein phosphat...3051e-128     376     57     73GO:0005829; C:cytosol; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0000159; C:protein phosphatase type 2A complex; TAS:TAIR.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0006470; P:protein dephosphorylation; TAS:TAIR.
59Q0E2S4    307   PP2A3_ORYSJ Serine/threonine-protein phosphat...3052e-128     375     57     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
60A2X2G3    307   PP2A3_ORYSI Serine/threonine-protein phosphat...3052e-128     375     57     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
61Q0DBD3    306   PP2A1_ORYSJ Serine/threonine-protein phosphat...3053e-128     375     57     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
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