UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDL046W

Length:

173

Number of sequences:

5887

Description:

YDL046W NPC2 SGDID:S000002204, Chr IV from 371240-371761, Genome Release 64-1-1, Verified ORF, "Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q12408	173	NPC2_YEAST Phosphatidylglycerol/phosphatidyli...	173	3e-121	346	100	100	GO:0000328; C:fungal-type vacuole lumen; IDA:SGD.
									GO:0032366; P:intracellular sterol transport; ISS:SGD.
2	Q6FNB1	185	NPC2_CANGA Phosphatidylglycerol/phosphatidyli...	181	1e-63	200	57	73
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
3	Q6CNE0	173	NPC2_KLULA Phosphatidylglycerol/phosphatidyli...	171	8e-63	197	60	73
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
4	Q756Q3	213	NPC2_ASHGO Phosphatidylglycerol/phosphatidyli...	139	5e-55	179	59	81
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
5	Q5A8A2	192	NPC2_CANAL Phosphatidylglycerol/phosphatidyli...	138	4e-49	163	59	75
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
6	Q6CHU5	189	NPC2_YARLI Phosphatidylglycerol/phosphatidyli...	134	4e-49	163	59	75
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
7	Q6BV42	196	NPC2_DEBHA Phosphatidylglycerol/phosphatidyli...	140	5e-47	158	55	73
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
8	Q52FS9	178	NPC2_MAGO7 Phosphatidylglycerol/phosphatidyli...	166	8e-35	126	45	64
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
9	Q7RZ85	177	NPC2_NEUCR Phosphatidylglycerol/phosphatidyli...	164	3e-34	124	43	63
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
10	Q4X136	175	NPC2_ASPFU Phosphatidylglycerol/phosphatidyli...	165	2e-33	122	41	61
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
11	P0CP28	180	NPC2_CRYNJ Phosphatidylglycerol/phosphatidyli...	129	2e-29	112	40	64
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
12	P0CP29	180	NPC2_CRYNB Phosphatidylglycerol/phosphatidyli...	129	2e-29	112	40	64
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
13	O94183	175	NPC2_ASPOR Phosphatidylglycerol/phosphatidyli...	157	3e-29	111	38	59	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
14	Q5B0Q1	169	NPC2_EMENI Phosphatidylglycerol/phosphatidyli...	162	1e-27	107	40	53
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
15	Q9C0X9	188	NPC2_SCHPO Phosphatidylglycerol/phosphatidyli...	143	2e-23	96.3	32	57	GO:0000328; C:fungal-type vacuole lumen; ISS:PomBase.
									GO:0032366; P:intracellular sterol transport; ISS:PomBase.
16	Q4P580	193	NPC2_USTMA Phosphatidylglycerol/phosphatidyli...	184	1e-22	94.4	31	51
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
17	Q54SZ9	147	Y2107_DICDI Putative phosphatidylglycerol/pho...	109	0.00000000000009	68.9	34	58
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
18	Q54YD2	141	Y8295_DICDI Putative phosphatidylglycerol/pho...	92	0.000000000003	64.7	37	60	GO:0005615; C:extracellular space; IDA:dictyBase.
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
19	Q54SZ8	142	NPC22_DICDI Putative phosphatidylglycerol/pho...	109	0.000000008	54.7	32	54
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
20	Q54KP7	151	NPC23_DICDI Putative phosphatidylglycerol/pho...	111	0.0000003	50.4	32	52
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
21	Q54SW1	145	Y2179_DICDI Putative phosphatidylglycerol/pho...	133	0.0000007	49.3	27	47
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
22	Q55BL4	151	NPC21_DICDI Putative phosphatidylglycerol/pho...	112	0.0000007	49.3	32	52
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
23	Q54MV4	153	Y8563_DICDI Putative phosphatidylglycerol/pho...	125	0.037	37	22	42
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
24	Q8CHT6	337	F169B_MOUSE Protein FAM169B OS=Mus musculus (...	49	0.52	33.9	33	53
25	O83184	197	Y149_TREPA Uncharacterized protein TP_0149 OS...	62	5.8	30.4	34	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
26	Q3SRV8	161	NUSB_NITWN N utilization substance protein B ...	39	7.6	30	33	54
									GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006353; P:transcription termination, DNA-dependent; IEA:UniProtKB-KW.

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