rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q639M6 | 245 | NPD_BACCZ NAD-dependent protein deacetylase O... | 254 | 2e-17 | 86.3 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 62 | Q81BT4 | 245 | NPD_BACCR NAD-dependent protein deacetylase O... | 254 | 2e-17 | 86.3 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 63 | F7EZ75 | 310 | SIR5_MACMU NAD-dependent protein deacylase si... | 293 | 4e-17 | 85.9 | 26 | 42 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 64 | Q5R6G3 | 310 | SIR5_PONAB NAD-dependent protein deacylase si... | 293 | 4e-17 | 85.9 | 26 | 41 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 65 | F7DKV7 | 309 | SIR5_XENTR NAD-dependent protein deacylase si... | 291 | 4e-17 | 85.9 | 28 | 43 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 66 | Q9NXA8 | 310 | SIR5_HUMAN NAD-dependent protein deacylase si... | 293 | 5e-17 | 85.5 | 26 | 41 | GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; IDA:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006342; P:chromatin silencing; TAS:ProtInc.::GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.::GO:0006476; P:protein deacetylation; IDA:UniProtKB. | 67 | Q8K2C6 | 310 | SIR5_MOUSE NAD-dependent protein deacylase si... | 309 | 6e-17 | 85.5 | 27 | 40 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 68 | Q8TWG0 | 250 | NPD_METKA NAD-dependent protein deacylase OS=... | 257 | 1e-16 | 84 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 69 | Q6HH09 | 245 | NPD_BACHK NAD-dependent protein deacetylase O... | 254 | 1e-16 | 83.6 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 70 | Q5SIH7 | 254 | NPD_THET8 NAD-dependent protein deacylase OS=... | 245 | 1e-16 | 83.6 | 24 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 71 | Q71W25 | 229 | NPD_LISMF NAD-dependent protein deacetylase O... | 242 | 2e-16 | 82.8 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 72 | Q8XNS6 | 244 | NPD_CLOPE NAD-dependent protein deacetylase O... | 256 | 2e-16 | 82.8 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 73 | Q839C6 | 237 | NPD_ENTFA NAD-dependent protein deacetylase O... | 255 | 2e-16 | 82.8 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 74 | O58669 | 249 | NPD_PYRHO NAD-dependent protein deacylase OS=... | 242 | 2e-16 | 82.8 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 75 | Q72IV5 | 254 | NPD_THET2 NAD-dependent protein deacylase OS=... | 245 | 3e-16 | 82.8 | 23 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 76 | B5YJW3 | 256 | NPD_THEYD NAD-dependent protein deacetylase O... | 231 | 5e-16 | 82 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 77 | Q9YB13 | 245 | NPD_AERPE NAD-dependent protein deacylase OS=... | 253 | 0.000000000000001 | 80.9 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 78 | E9GD30 | 274 | SIR5_DAPPU NAD-dependent protein deacylase OS... | 300 | 0.000000000000003 | 79.7 | 25 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 79 | A9SDL4 | 323 | SIR5_PHYPA NAD-dependent protein deacylase OS... | 240 | 0.000000000000003 | 80.1 | 28 | 44 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 80 | Q8R9N6 | 242 | NPD1_THETN NAD-dependent protein deacylase 1 ... | 237 | 0.000000000000009 | 78.2 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 81 | Q88BY5 | 262 | NPD_PSEPK NAD-dependent protein deacylase OS=... | 240 | 0.00000000000001 | 77.8 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 82 | Q8IE47 | 273 | SIR5_PLAF7 NAD-dependent protein deacylase Si... | 259 | 0.00000000000002 | 77.4 | 25 | 39 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 83 | Q9UR39 | 415 | HST4_SCHPO NAD-dependent protein deacetylase ... | 294 | 0.00000000000002 | 79.3 | 28 | 43 | GO:0016585; C:chromatin remodeling complex; ISS:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0017136; F:NAD-dependent histone deacetylase activity; TAS:PomBase.::GO:0003714; F:transcription corepressor activity; IMP:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0071572; P:histone H3-K56 deacetylation; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:2000283; P:negative regulation of cellular amino acid biosynthetic process; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006282; P:regulation of DNA repair; IMP:PomBase.::GO:0060303; P:regulation of nucleosome density; IEP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 84 | Q8U1Q1 | 250 | NPD_PYRFU NAD-dependent protein deacylase OS=... | 233 | 0.00000000000003 | 76.6 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 85 | Q5HM33 | 246 | NPD_STAEQ NAD-dependent protein deacetylase O... | 250 | 0.00000000000003 | 76.6 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 86 | Q8Y3U2 | 229 | NPD_LISMO NAD-dependent protein deacetylase O... | 237 | 0.00000000000003 | 76.3 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 87 | Q8CNF4 | 246 | NPD_STAES NAD-dependent protein deacetylase O... | 250 | 0.00000000000003 | 76.3 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 88 | Q927A7 | 229 | NPD_LISIN NAD-dependent protein deacetylase O... | 238 | 0.00000000000003 | 76.3 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 89 | Q974M6 | 250 | NPD_SULTO NAD-dependent protein deacetylase O... | 247 | 0.00000000000004 | 75.9 | 27 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 90 | Q6N6U0 | 253 | NPD_RHOPA NAD-dependent protein deacetylase O... | 252 | 0.00000000000005 | 75.9 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 91 | Q1JQC6 | 315 | SIR4_BOVIN NAD-dependent protein deacetylase ... | 286 | 0.00000000000006 | 76.3 | 26 | 45 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. |