Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL042C
Length:
562
Number of sequences:
5887
Description:
YDL042C SIR2 SGDID:S000002200, Chr IV from 378445-376757, Genome Release 64-1-1, reverse complement, Verified ORF, "Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q4UZX0    293   NPD_XANC8 NAD-dependent protein deacetylase O...2320.000000000004     70.5     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
122Q73WM7    237   NPD_MYCPA NAD-dependent protein deacylase OS=...2390.000000000008     68.9     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
123Q97MB4    245   NPD_CLOAB NAD-dependent protein deacetylase O...2510.000000000008     68.9     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
124Q9KEE5    237   NPD_BACHD NAD-dependent protein deacetylase O...2610.000000000009     68.6     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
125Q8FRV5    254   NPD2_COREF NAD-dependent protein deacylase 2 ...2360.00000000001     68.9     25     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
126Q6MJJ2    235   NPD_BDEBA NAD-dependent protein deacylase OS=...2430.00000000001     68.2     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
127Q8FUC8    281   NPD1_COREF NAD-dependent protein deacetylase ...2620.00000000001     68.9     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
128Q6A5T5    244   NPD_PROAC NAD-dependent protein deacetylase O...2570.00000000001     68.2     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
129A0QDH4    282   NPD1_MYCA1 NAD-dependent protein deacetylase ...2560.00000000002     68.2     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0019213; F:deacetylase activity; IEA:HAMAP.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:HAMAP.
GO:0006476; P:protein deacetylation; IEA:InterPro.
130Q20480    287   SIR41_CAEEL NAD-dependent protein deacetylase...2480.00000000002     68.6     27     44
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.
131Q20481    287   SIR42_CAEEL NAD-dependent protein deacetylase...2820.00000000002     68.6     24     44
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0006476; P:protein deacetylation; IEA:InterPro.
132Q4JBN2    252   NPD_SULAC NAD-dependent protein deacetylase O...2270.00000000002     67.8     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
133Q94AQ6    373   SIR4_ARATH NAD-dependent protein deacetylase ...2560.00000000002     69.3     26     40GO:0005634; C:nucleus; IDA:TAIR.
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0031348; P:negative regulation of defense response; IMP:TAIR.::GO:0006476; P:protein deacetylation; IEA:InterPro.
134Q5WKC8    237   NPD_BACSK NAD-dependent protein deacetylase O...2550.00000000002     67.4     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
135Q8NSM4    258   NPD_CORGL NAD-dependent protein deacylase OS=...2660.00000000003     67.4     25     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
136Q89EA6    273   NPD2_BRAJA NAD-dependent protein deacetylase ...2270.00000000003     67.8     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
137Q8Y015    246   NPD_RALSO NAD-dependent protein deacylase OS=...2530.00000000004     67     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
138B8ARK7    484   SIR1_ORYSI NAD-dependent protein deacetylase ...2360.00000000005     68.9     24     44
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
139Q9FE17    473   SIR1_ARATH NAD-dependent protein deacetylase ...3030.00000000007     68.2     23     41
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
140B0RM75    293   NPD_XANCB NAD-dependent protein deacetylase O...2390.0000000001     66.2     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
141Q899G3    247   NPD_CLOTE NAD-dependent protein deacetylase O...2510.0000000001     65.5     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
142A0QC96    233   NPD2_MYCA1 NAD-dependent protein deacylase 2 ...2360.0000000002     64.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
143P66813    237   NPD_MYCTU NAD-dependent protein deacylase OS=...2390.0000000002     64.7     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0003953; F:NAD+ nucleosidase activity; IDA:MTBBASE.::GO:0034979; F:NAD-dependent protein deacetylase activity; IDA:MTBBASE.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070213; P:protein auto-ADP-ribosylation; IDA:MTBBASE.::GO:0006476; P:protein deacetylation; IDA:MTBBASE.
144P66814    237   NPD_MYCBO NAD-dependent protein deacylase OS=...2390.0000000002     64.7     24     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
145Q9RL35    299   NPD1_STRCO NAD-dependent protein deacetylase ...2100.0000000004     64.7     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
146Q95Q89    292   SIR24_CAEEL NAD-dependent protein deacetylase...2380.0000000008     63.5     24     39
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
147Q4Q2Y6    243   SIR5_LEIMA NAD-dependent protein deacetylase ...2430.000000001     62.4     27     42
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
148A9A0B2    273   NPD_DESOH NAD-dependent protein deacylase OS=...2460.000000001     62.8     25     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
149F7D4X9    315   SIR5_MONDO NAD-dependent protein deacylase si...1570.000000001     63.5     29     45
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
150P59941    334   SIR6_MOUSE NAD-dependent protein deacetylase ...2760.000000001     63.5     25     41GO:0005724; C:nuclear telomeric heterochromatin; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); ISS:UniProtKB.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.
151Q4QB33    320   SIR4_LEIMA NAD-dependent protein deacetylase ...2750.000000002     63.2     25     39
GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006476; P:protein deacetylation; IEA:InterPro.
records
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