Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL028C
Length:
764
Number of sequences:
5887
Description:
YDL028C MPS1 SGDID:S000002186, Chr IV from 403291-400997, Genome Release 64-1-1, reverse complement, Verified ORF, "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721Q5RCC4    478   KCC2A_PONAB Calcium/calmodulin-dependent prot...2910.00000000000003     79.3     27     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
722Q9UQM7    478   KCC2A_HUMAN Calcium/calmodulin-dependent prot...2910.00000000000003     79.3     27     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
723Q9YHZ5    310   PIM2_DANRE Serine/threonine-protein kinase pi...3130.00000000000003     77.8     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; NAS:ZFIN.
724P05383    351   KAPCB_PIG cAMP-dependent protein kinase catal...2570.00000000000003     78.2     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
725P04409    672   KPCA_BOVIN Protein kinase C alpha type OS=Bos...2950.00000000000003     80.1     25     44GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
726P08414    469   KCC4_MOUSE Calcium/calmodulin-dependent prote...2810.00000000000003     79.3     30     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:MGI.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:MGI.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0007165; P:signal transduction; IDA:MGI.
727Q8N4C8    1332   MINK1_HUMAN Misshapen-like kinase 1 OS=Homo s...2890.00000000000003     80.5     25     44GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.::GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; IMP:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; IMP:UniProtKB.::GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; ISS:UniProtKB.
728P54665    345   CC2H2_TRYBB Cell division control protein 2 h...3100.00000000000003     78.2     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
729Q42438    533   CDPK8_ARATH Calcium-dependent protein kinase ...2690.00000000000003     79.7     26     45GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
730C0RW22    468   CDK14_DASNO Cyclin-dependent kinase 14 OS=Das...2150.00000000000003     79.3     30     45GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
731P87050    775   CDR2_SCHPO Mitosis inducer protein kinase cdr...2810.00000000000003     80.1     26     44GO:0071341; C:medial cortical node; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IGI:PomBase.::GO:0071574; P:protein localization to medial cortex; IMP:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0008361; P:regulation of cell size; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
732Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...3060.00000000000003     80.5     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
733Q9Z1B7    366   MK13_MOUSE Mitogen-activated protein kinase 1...2360.00000000000003     78.6     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
734Q8W490    470   PEPK2_ARATH Serine/threonine-protein kinase P...2710.00000000000003     79.3     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
735Q4WSF6    366   HOG1_ASPFU Mitogen-activated protein kinase h...2330.00000000000003     78.6     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
736Q8BPM2    847   M4K5_MOUSE Mitogen-activated protein kinase k...3150.00000000000004     80.1     25     44GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
737P43057    1097   KPC1_CANAX Protein kinase C-like 1 OS=Candida...3000.00000000000004     80.5     26     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
738Q6Z437    370   MPK3_ORYSJ Mitogen-activated protein kinase 3...3160.00000000000004     78.6     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
739B7ZR30    950   STK10_XENLA Serine/threonine-protein kinase 1...2840.00000000000004     80.1     24     45GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
740A1CPG7    365   HOG1_ASPCL Mitogen-activated protein kinase h...2330.00000000000004     78.2     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
741P05696    672   KPCA_RAT Protein kinase C alpha type OS=Rattu...2950.00000000000004     79.7     25     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007568; P:aging; IEP:RGD.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:RGD.::GO:0045184; P:establishment of protein localization; TAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0017148; P:negative regulation of translation; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IDA:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:RGD.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0051965; P:positive regulation of synapse assembly; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0048259; P:regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0046677; P:response to antibiotic; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IMP:RGD.::GO:0045471; P:response to ethanol; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; IMP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.
742O93982    431   HOG1_ZYGRC Mitogen-activated protein kinase H...2360.00000000000004     79     28     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
743Q9Y2U5    619   M3K2_HUMAN Mitogen-activated protein kinase k...2500.00000000000004     79.7     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
744Q641K5    658   NUAK1_MOUSE NUAK family SNF1-like kinase 1 OS...2830.00000000000004     79.7     25     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
745P20444    672   KPCA_MOUSE Protein kinase C alpha type OS=Mus...2950.00000000000004     79.7     25     43GO:0030425; C:dendrite; IDA:MGI.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0002062; P:chondrocyte differentiation; IDA:MGI.::GO:0000188; P:inactivation of MAPK activity; IMP:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0050930; P:induction of positive chemotaxis; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0046325; P:negative regulation of glucose import; IMP:MGI.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:MGI.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0030593; P:neutrophil chemotaxis; IMP:MGI.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; IMP:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050729; P:positive regulation of inflammatory response; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0006937; P:regulation of muscle contraction; IMP:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:MGI.
746P00516    671   KGP1_BOVIN cGMP-dependent protein kinase 1 OS...2720.00000000000004     79.7     26     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB.
GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.
747Q54QB1    369   ERK2_DICDI Extracellular signal-regulated kin...3140.00000000000004     78.2     24     46GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; IGI:dictyBase.
748Q61241    365   TSSK1_MOUSE Testis-specific serine/threonine-...2370.00000000000004     78.2     27     44GO:0001669; C:acrosomal vesicle; TAS:UniProtKB.::GO:0019861; C:flagellum; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; IMP:UniProtKB.
749P39009    513   DUN1_YEAST DNA damage response protein kinase...2400.00000000000004     79.3     25     44GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000077; P:DNA damage checkpoint; IMP:SGD.::GO:0048478; P:replication fork protection; IGI:SGD.
750O77676    671   KGP1_RABIT cGMP-dependent protein kinase 1 OS...2720.00000000000004     79.7     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB.
GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.
751Q13976    671   KGP1_HUMAN cGMP-dependent protein kinase 1 OS...2720.00000000000004     79.7     26     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; IDA:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0090331; P:negative regulation of platelet aggregation; IMP:UniProtKB.::GO:0043087; P:regulation of GTPase activity; IMP:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
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