Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL028C
Length:
764
Number of sequences:
5887
Description:
YDL028C MPS1 SGDID:S000002186, Chr IV from 403291-400997, Genome Release 64-1-1, reverse complement, Verified ORF, "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
631Q551H4    1028   FRAY2_DICDI Serine/threonine-protein kinase f...3260.00000000000001     82     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
632P12688    680   YPK1_YEAST Serine/threonine-protein kinase YP...2740.00000000000001     81.6     26     46GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0070941; P:eisosome assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0061093; P:negative regulation of phospholipid translocation; IMP:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
633A4IIW7    423   CDK14_XENTR Cyclin-dependent kinase 14 OS=Xen...2160.00000000000001     80.5     31     47GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
634P34947    590   GRK5_HUMAN G protein-coupled receptor kinase ...2290.00000000000001     81.3     29     45GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005080; F:protein kinase C binding; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:ProtInc.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
635Q753D9    726   PKH3_ASHGO Serine/threonine-protein kinase PK...2920.00000000000001     81.6     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
636Q750A9    447   HOG1_ASHGO Mitogen-activated protein kinase H...2360.00000000000001     80.5     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
637Q10SC8    456   CIPK9_ORYSJ CBL-interacting protein kinase 9 ...2420.00000000000001     80.5     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
638Q923T9    529   KCC2G_MOUSE Calcium/calmodulin-dependent prot...2990.00000000000001     80.9     26     41GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IMP:MGI.
639Q5JLD8    446   CIPK8_ORYSJ CBL-interacting protein kinase 8 ...2250.00000000000001     80.5     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
640P22694    351   KAPCB_HUMAN cAMP-dependent protein kinase cat...2570.00000000000001     79.3     27     44GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome.
641P23298    683   KPCL_MOUSE Protein kinase C eta type OS=Mus m...2910.00000000000001     81.3     27     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB.
642Q5QNM6    511   CIPKD_ORYSJ Putative CBL-interacting protein ...2900.00000000000001     80.9     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
643Q0U4L8    355   HOG1_PHANO Mitogen-activated protein kinase H...2330.00000000000001     79.3     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
644Q4W6D3    355   HOG1_COCHE Mitogen-activated protein kinase H...3100.00000000000001     79.3     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
645E1BB50    1264   CDK12_BOVIN Cyclin-dependent kinase 12 OS=Bos...3350.00000000000001     81.6     27     44GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
646O61125    461   STK4_DICDI Serine/threonine-protein kinase 4 ...2760.00000000000001     80.5     24     43GO:0005938; C:cell cortex; IMP:dictyBase.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0006972; P:hyperosmotic response; IMP:dictyBase.::GO:0045762; P:positive regulation of adenylate cyclase activity; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0007165; P:signal transduction; IMP:dictyBase.
647Q64617    683   KPCL_RAT Protein kinase C eta type OS=Rattus ...2910.00000000000001     81.3     27     44GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070528; P:protein kinase C signaling cascade; IMP:RGD.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB.
648P36583    1016   PCK2_SCHPO Protein kinase C-like 2 OS=Schizos...3180.00000000000001     81.6     24     42GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005622; C:intracellular; IC:GOC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004697; F:protein kinase C activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0035556; P:intracellular signal transduction; IC:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0032949; P:regulation of alpha-glucan biosynthetic process; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
649Q12851    820   M4K2_HUMAN Mitogen-activated protein kinase k...2800.00000000000001     81.3     26     45GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:ProtInc.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0006903; P:vesicle targeting; NAS:UniProtKB.
650Q75L42    454   CIPKH_ORYSJ CBL-interacting protein kinase 17...1760.00000000000001     80.5     34     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
651O55098    966   STK10_MOUSE Serine/threonine-protein kinase 1...3090.00000000000002     81.6     24     44GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
652Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...2810.00000000000002     80.9     25     45
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
653Q61161    821   M4K2_MOUSE Mitogen-activated protein kinase k...2800.00000000000002     81.3     25     45GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006903; P:vesicle targeting; IDA:UniProtKB.
654Q99759    626   M3K3_HUMAN Mitogen-activated protein kinase k...2680.00000000000002     80.9     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.
655Q7ZVS3    940   PLK4_DANRE Serine/threonine-protein kinase PL...2820.00000000000002     81.3     26     48GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.
656Q90327    427   MK08A_CYPCA Mitogen-activated protein kinase ...1380.00000000000002     80.1     34     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
657A8WUG4    597   KPC3_CAEBR Protein kinase C-like 3 OS=Caenorh...3100.00000000000002     80.9     25     45GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
658A8WXF6    533   KCC2D_CAEBR Calcium/calmodulin-dependent prot...2940.00000000000002     80.5     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
659Q1DUU8    364   HOG1_COCIM Mitogen-activated protein kinase H...2330.00000000000002     79.3     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
660Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...2810.00000000000002     80.9     25     46
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
661E1BK52    966   STK10_BOVIN Serine/threonine-protein kinase 1...3000.00000000000002     81.3     24     45GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
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