Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL028C
Length:
764
Number of sequences:
5887
Description:
YDL028C MPS1 SGDID:S000002186, Chr IV from 403291-400997, Genome Release 64-1-1, reverse complement, Verified ORF, "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P27638    372   SPK1_SCHPO Mitogen-activated protein kinase s...3153e-18     90.9     26     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IGI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; IMP:PomBase.
182P25389    1037   KCC4_YEAST Probable serine/threonine-protein ...2903e-18     93.6     28     46GO:0032174; C:cellular bud neck septin collar; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005940; C:septin ring; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007117; P:budding cell bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0000135; P:septin checkpoint; IGI:SGD.::GO:0000921; P:septin ring assembly; IMP:SGD.
183Q86CS2    668   ATG1_DICDI Serine/threonine-protein kinase at...2403e-18     93.2     30     48GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0048102; P:autophagic cell death; IMP:dictyBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:dictyBase.::GO:0016236; P:macroautophagy; IMP:dictyBase.::GO:0070265; P:necrotic cell death; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
184Q86AD7    392   MYLKB_DICDI Probable myosin light chain kinas...2823e-18     91.3     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
185Q9Y2H1    464   ST38L_HUMAN Serine/threonine-protein kinase 3...2843e-18     92     27     44GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
186O15865    513   CDPK2_PLAFK Calcium-dependent protein kinase ...2803e-18     92.4     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
187Q99683    1374   M3K5_HUMAN Mitogen-activated protein kinase k...2803e-18     94     30     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.::GO:0010421; P:hydrogen peroxide-mediated programmed cell death; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
188Q6FN53    915   STE20_CANGA Serine/threonine-protein kinase S...3483e-18     93.2     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
189O97143    769   PLK4_DROME Serine/threonine-protein kinase PL...3093e-18     93.2     27     47GO:0005814; C:centriole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase.
190P93101    294   CDC2_CHERU Cell division control protein 2 ho...3054e-18     89.7     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
191Q6BS08    875   ATG1_DEBHA Serine/threonine-protein kinase AT...3024e-18     93.2     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
192Q9JI10    497   STK3_MOUSE Serine/threonine-protein kinase 3 ...3094e-18     92     27     46GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0060215; P:primitive hemopoiesis; IGI:MGI.
193Q08217    1101   PSK2_YEAST Serine/threonine-protein kinase PS...2944e-18     93.2     25     46GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
194Q6C7U8    294   PHO85_YARLI Negative regulator of the PHO sys...2234e-18     89.7     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
195O22040    666   ANP1_ARATH Mitogen-activated protein kinase k...2884e-18     92.4     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
196O35099    1380   M3K5_MOUSE Mitogen-activated protein kinase k...2804e-18     93.2     30     45GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
197Q6DT37    1551   MRCKG_HUMAN Serine/threonine-protein kinase M...2754e-18     93.2     28     48GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
198Q8SR90    309   Y8H9_ENCCU Probable cell division protein kin...2224e-18     89.7     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
199Q27032    298   CDC2H_THEPA Cell division control protein 2 h...3055e-18     89.4     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
200B4IAQ8    769   PLK4_DROSE Serine/threonine-protein kinase PL...3175e-18     92.4     26     46GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
201Q9W739    302   CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana ...3095e-18     89.4     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
202Q9XZD6    288   CDC2H_PLAVI Cell division control protein 2 h...3035e-18     89.4     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
203P51955    445   NEK2_HUMAN Serine/threonine-protein kinase Ne...2306e-18     90.9     28     50GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051299; P:centrosome separation; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
204Q6IP06    493   STK3_XENLA Serine/threonine-protein kinase 3 ...3036e-18     91.3     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
205Q16W24    769   PLK4_AEDAE Serine/threonine-protein kinase PL...2856e-18     92.4     26     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
206P04551    297   CDK1_SCHPO Cyclin-dependent kinase 1 OS=Schiz...3096e-18     89     27     43GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; TAS:PomBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; TAS:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0008361; P:regulation of cell size; NAS:PomBase.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; TAS:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; NAS:PomBase.
207O65554    441   CIPK6_ARATH CBL-interacting serine/threonine-...2856e-18     90.9     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0042538; P:hyperosmotic salinity response; IDA:TAIR.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
208B3DL84    946   PLK4_XENTR Serine/threonine-protein kinase PL...2847e-18     92.4     26     49GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.
209Q38772    294   CDC2A_ANTMA Cell division control protein 2 h...3057e-18     89     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
210P41808    388   SMK1_YEAST Sporulation-specific mitogen-activ...3187e-18     90.1     27     46GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:SGD.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0042174; P:negative regulation of sporulation resulting in formation of a cellular spore; IGI:SGD.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
211P00518    387   PHKG1_RABIT Phosphorylase b kinase gamma cata...2947e-18     89.7     28     48GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
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