Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL020C
Length:
531
Number of sequences:
5887
Description:
YDL020C RPN4 SGDID:S000002178, Chr IV from 416708-415113, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P39956    796   RPH1_YEAST DNA damage-responsive transcriptio...750.82     36.2     28     45GO:0005634; C:nucleus; IC:SGD.
GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:SGD.::GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:SGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
62Q28G88    435   FEZF2_XENTR Fez family zinc finger protein 2 ...740.83     35.8     31     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63P51774    470   EGR2_RAT E3 SUMO-protein ligase EGR2 OS=Rattu...780.86     35.8     35     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007611; P:learning or memory; IEP:RGD.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:RGD.
64P08152    470   EGR2_MOUSE E3 SUMO-protein ligase EGR2 OS=Mus...780.86     35.8     35     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035284; P:brain segmentation; IMP:MGI.::GO:0071310; P:cellular response to organic substance; IDA:MGI.::GO:0021612; P:facial nerve structural organization; IGI:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0042552; P:myelination; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006611; P:protein export from nucleus; IDA:UniProtKB.::GO:0030278; P:regulation of ossification; IMP:MGI.::GO:0021660; P:rhombomere 3 formation; IMP:MGI.::GO:0021666; P:rhombomere 5 formation; IMP:MGI.::GO:0007622; P:rhythmic behavior; IDA:MGI.::GO:0014037; P:Schwann cell differentiation; IMP:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
65O95365    584   ZBT7A_HUMAN Zinc finger and BTB domain-contai...550.9     35.8     36     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
66P11161    476   EGR2_HUMAN E3 SUMO-protein ligase EGR2 OS=Hom...780.91     35.8     35     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
67Q8N7M2    679   ZN283_HUMAN Zinc finger protein 283 OS=Homo s...742.8     34.3     36     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68Q9QZ48    569   ZBT7A_RAT Zinc finger and BTB domain-containi...550.92     35.8     36     45GO:0005634; C:nucleus; IDA:RGD.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045670; P:regulation of osteoclast differentiation; IDA:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69Q6NXK2    1036   ZN532_MOUSE Zinc finger protein 532 OS=Mus mu...580.95     36.2     33     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70O88939    569   ZBT7A_MOUSE Zinc finger and BTB domain-contai...550.96     35.8     36     45GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051216; P:cartilage development; NAS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
71Q08427    421   EGR2_XENLA Early growth response protein 2 OS...781     35.8     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72Q6ZMS4    509   ZN852_HUMAN Putative zinc finger protein 852 ...721.1     35.8     35     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
73Q01713    244   KLF9_RAT Krueppel-like factor 9 OS=Rattus nor...611.1     35     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q5RE50    517   ZN215_PONAB Zinc finger protein 215 OS=Pongo ...552.4     34.7     40     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
75Q2TAR3    434   FEZF2_XENLA Fez family zinc finger protein 2 ...741.1     35.4     31     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q95K52    654   ZN283_MACFA Zinc finger protein 283 OS=Macaca...531.3     35.4     42     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77Q05159    412   EGR2B_DANRE Early growth response protein 2b ...781.2     35.4     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78Q14592    562   ZN460_HUMAN Zinc finger protein 460 OS=Homo s...1123.8     33.9     28     36GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
79Q3Y4E1    794   ZN148_BOVIN Zinc finger protein 148 OS=Bos ta...1491.4     35.4     27     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80Q61624    794   ZN148_MOUSE Zinc finger protein 148 OS=Mus mu...1491.4     35.4     27     40GO:0005634; C:nucleus; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007276; P:gamete generation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81Q8WTR7    871   ZN473_HUMAN Zinc finger protein 473 OS=Homo s...1181.4     35.4     30     46GO:0015030; C:Cajal body; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006398; P:histone mRNA 3'-end processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
82Q15937    498   ZNF79_HUMAN Zinc finger protein 79 OS=Homo sa...531.4     35.4     42     55GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
83Q9UQR1    794   ZN148_HUMAN Zinc finger protein 148 OS=Homo s...1491.5     35.4     27     40GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
84Q9Z0Z7    446   KLF5_MOUSE Krueppel-like factor 5 OS=Mus musc...1101.5     35     31     44GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IMP:MGI.::GO:0030033; P:microvillus assembly; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
85Q60793    483   KLF4_MOUSE Krueppel-like factor 4 OS=Mus musc...551.5     35     36     49
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009913; P:epidermal cell differentiation; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0031077; P:post-embryonic camera-type eye development; IMP:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0019827; P:stem cell maintenance; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
86O43474    513   KLF4_HUMAN Krueppel-like factor 4 OS=Homo sap...551.5     35     36     49GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.::GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046985; P:positive regulation of hemoglobin biosynthetic process; IMP:BHF-UCL.::GO:0035166; P:post-embryonic hemopoiesis; IMP:BHF-UCL.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
87Q5R782    794   ZN148_PONAB Zinc finger protein 148 OS=Pongo ...1491.6     35.4     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
88P0CG31    522   Z286B_HUMAN Putative zinc finger protein 286B...801.6     35     30     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89Q62806    794   ZN148_RAT Zinc finger protein 148 OS=Rattus n...1491.6     35.4     27     40GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90Q3SY56    376   SP6_HUMAN Transcription factor Sp6 OS=Homo sa...561.7     35     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91Q5T619    568   ZN648_HUMAN Zinc finger protein 648 OS=Homo s...1381.7     35     28     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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